Results 181 to 190 of about 34,135 (204)
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Olaparib

Reactions Weekly, 2018
Olaparib (Lynparza [AstraZeneca, Cambridge, UK], formerly referred to as AZD2281 or KU0059436) is an oral poly(ADP-ribose) polymerase (PARP) inhibitor. It is rationally designed to act as a competitive inhibitor of NAD+ at the catalytic site of PARP1 and PARP2, both members of the PARP family of enzymes that are central to the repair of DNA single ...
Sylvia, Bochum   +2 more
  +5 more sources

Adjuvant olaparib — should all patients with breast cancer have genetic testing?

Nature Reviews Clinical Oncology, 2021
Steven A Narod
exaly  

Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer

New England Journal of Medicine, 2020
Maha H A Hussain   +2 more
exaly  

Olaparib for Metastatic Castration-Resistant Prostate Cancer

New England Journal of Medicine, 2020
Johann Sebastian de Bono   +2 more
exaly  

Olaparib for DNA repair-deficient prostate cancer — one for all, or all for one?

Nature Reviews Clinical Oncology, 2020
Emmanuel S Antonarakis Mbbch
exaly  

Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer

New England Journal of Medicine, 2019
Isabelle Ray-Coquard   +2 more
exaly  

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