Results 31 to 40 of about 665 (160)
ChemMedChem, Volume 17, Issue 21, November 4, 2022., 2022 Anticancer compounds with heart: This manuscript reports the synthesis of derivatives of Antiaris toxicaria 2 (cardiac glycosides). Biological evaluation of these analogues in the signalling of the DNA damage response indicate that their activity can be enhanced by tuning key structural moieties.
Diana Ainembabazi +4 more
wiley +1 more source
Oxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022 Objective. Although the expression of long noncoding RNAs (lncRNAs) and N6‐methyladenosine (M6A) is correlated with different tumors, it remains unclear how M6A‐related lncRNA functioning affects the initiation and progression of oral squamous cell carcinoma (OSCC). Materials and Methods. Gene expression and clinical data were retrieved from The Cancer
Li Shan +7 more
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Ecology and Evolution, Volume 11, Issue 24, Page 18042-18054, December 2021., 2021 We found that dietary cardenolides can increase growth, developmental speed, and longevity in milkweed bugs (Heteroptera: Lygaeinae). Abstract Sequestration, that is, the accumulation of plant toxins into body tissues for defense, was predicted to incur physiological costs and may require resistance traits different from those of non‐sequestering ...
Prayan Pokharel +2 more
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Ciência Rural, 2023 : Nerium oleander, also known as “espirradeira” in Brazil, is a shrub or small tree widely used as an ornamental plant in temperate and subtropical regions of the world. Ingestion of N.
Alexia Amanda Zorzan +8 more
doaj +1 more source
Arhiv za Higijenu Rada i Toksikologiju, 2023 Natural cardiac glycosides have positive inotropic heart effects but at high, toxic doses they can cause life-threatening cardiac arrhythmias. Here we present the first Croatian case of a 16-year-old girl who attempted suicide by eating dried oleander ...
Kovačević Tanja +6 more
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Toxins, 2020 Cardiac glycosides (CGs) are naturally occurring plant secondary metabolites that can be toxic to humans and animals. The aim of this work was to develop a targeted analytical method utilizing liquid chromatography—tandem mass spectrometry (LC-MS/MS) for
Svetlana V. Malysheva +2 more
doaj +1 more source
Pharmacokinetics of Oleandrin Following Administration of a Nerium oleander Extract in Mice [PDF]
Batna Journal of Medical SciencesBackground. Nerium oleander Linn is native of Mediterranean regions of Africa and Europe, where it is used in folk medical practices. The whole plant is known to be toxic.
Sara ABDENNOUR +5 more
doaj +1 more source
5α-Oleandrin reduce Bcl-2 protein and increase Bax protein expression on Hela cervical cancer cell
Universa Medicina, 2017 BACKGROUND The leaves of Nerium indicum Mill. have been utilized traditionally to cure cancer. By using Bioassay guided extraction and isolation method, three compounds (NiO-1, NiO-2, NiO-3) were isolated from an active fraction of the CHCl3 extract of ...
Mae Sri Hartati Wahyuningsih +4 more
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Toxins, 2020 Oleander is a spontaneous shrub widely occurring in Mediterranean regions. Poisoning is sporadically reported in livestock, mainly due to the ingestion of leaves containing toxic cardiac glycosides (primarily oleandrin).
Luigi Ceci +8 more
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, 2021 Journal of the American College of Emergency Physicians Open, Volume 2, Issue 4, August 2021.
Michael A. DiPietro, Christopher Mondie
wiley +1 more source