Results 31 to 40 of about 873 (179)
Chemotherapeutic agents have been linked to immunogenic cell death (ICD) induction that is capable of augmenting anti-tumor immune surveillance. The cardiac glycoside oleandrin, which inhibits Na+/K+-ATPase pump (NKP), has been shown to suppress breast ...
Xiaoxi Li +5 more
doaj +1 more source
Glioblastoma multiforme (GBM) is the most common as well as one of the most malignant types of brain cancer. Despite progress in development of novel therapies for the treatment of GBM, it remains largely incurable with a poor prognosis and a very low ...
Alessandro Colapietro +14 more
doaj +1 more source
Figure 19. Sulfated galactan, Figure 20. Oleandrin
Figure 19. Sulfated galactan spiderchem ID : N/A Figure 20.
Adryan Fristiohady (12512725)
core +1 more source
Biliary parascarosis in a foal
Here we report finding of an adult male Parascaris nematode in the junction of the lobar duct and left hepatic duct during necropsy of a 6‐month‐old female foal who died because of oleander (Nerium oleander) intoxication. Abstract Migration of Ascaris lumbricoides through the papilla of Vater in humans, and entry into the biliary tree, is well ...
Alireza Sazmand +4 more
wiley +1 more source
Microbial biotransformation is an important tool in drug discovery and for metabolism studies. To expand our bioactive natural product library via modification and to identify possible mammalian metabolites, a cytotoxic cardenolide (gitoxigenin) was ...
Erdal Bedir +5 more
doaj +1 more source
Development of α-Selective Glycosylation with l-Oleandral and Its Application to the Total Synthesis of Oleandrin. [PDF]
This letter describes the development of an α-selective glycosylation using l-oleandrose, a 2-deoxysugar that is frequently found in natural products, and its application to the total synthesis of the natural cardiotonic steroids oleandrin and ...
Carney N +3 more
europepmc +2 more sources
We raised milkweed bugs on artificial diets with increasing quantities of cardenolides and then examined how this affected oxidative state and signal quality (brightness and chroma) across different life stages. Glutathione decreased in all individuals with increasing levels of sequestered cardenolides.
H. Cecilia Heyworth +5 more
wiley +1 more source
Cosmetics and personal care items are used worldwide and administered straight to the skin. The hazardous nature of the chemical surfactant utilized in the production of cosmetics has caused alarm on a global scale. Therefore, bacterial biosurfactants (BS) are becoming increasingly popular in industrial product production as a biocompatible, low‐toxic ...
Arun Karnwal +9 more
wiley +1 more source
Treatment of rhabdomyosarcoma (RMS), the most common a soft tissue sarcoma in childhood, provides intensive multimodal therapy, with radiotherapy (RT) playing a critical role for local tumor control. However, since RMS efficiently activates mechanisms of
Sara Vaccaro +30 more
doaj +1 more source
Stimuli‐responsive crosslinked nanomedicine for cancer treatment
We classify the stimuli‐responsive crosslinked nanomedicines (SCNs) into three categories based on the crosslinking strategies, including built‐in, on‐surface, and inter‐particle crosslinking nanomedicines. These SCNs can respond to particular tumoral stimuli and go through a series of dynamic changes to circumvent different biological barriers, and ...
Xiangdong Xue, Haijing Qu, Yuanpei Li
wiley +1 more source

