Results 71 to 80 of about 115,804 (336)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

Corticofugal projections from the anterior olfactory nucleus target olfactory bulb principal cells [PDF]

open access: yes, 2011
The anterior olfactory nucleus (AON) is a cortical structure reciprocally connected with the olfactory bulb (OB) and the piriform cortex. Here, using small extracellular and intracellular injections to trace the terminal projections in the OB from ...
Kurt R. Illig
core   +2 more sources

Odor identity coding by distributed ensembles of neurons in the mouse olfactory cortex

open access: yeseLife, 2017
Olfactory perception and behaviors critically depend on the ability to identify an odor across a wide range of concentrations. Here, we use calcium imaging to determine how odor identity is encoded in olfactory cortex.
Benjamin Roland   +4 more
doaj   +1 more source

Spared piriform cortical single-unit odor processing and odor discrimination in the Tg2576 mouse model of Alzheimer's disease. [PDF]

open access: yesPLoS ONE, 2014
Alzheimer's disease is a neurodegenerative disorder that is the most common cause of dementia in the elderly today. One of the earliest reported signs of Alzheimer's disease is olfactory dysfunction, which may manifest in a variety of ways.
Wenjin Xu   +7 more
doaj   +1 more source

Top-down feedback enables flexible coding strategies in the olfactory cortex

open access: yesCell Reports, 2022
Summary: In chemical sensation, multiple models have been proposed to explain how odors are represented in the olfactory cortex. One hypothesis is that the combinatorial identity of active neurons within sniff-related time windows is critical, whereas ...
Zhen Chen, Krishnan Padmanabhan
doaj   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

open access: yesAdvanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram   +10 more
wiley   +1 more source

Brain Activations in Response to Prolonged Citral Inhalation Detected by Manganese-Enhanced Magnetic Resonance Imaging (MEMRI)

open access: yesChinese Journal of Magnetic Resonance, 2020
In this study, an olfactory inhalation instrument was devised to allow the rats to inhale volatile citral or odorless air. Manganese-enhanced magnetic resonance imaging (MEMRI) was used to reveal changes of accumulative brain activities after a 24 h ...
FANG Wen-heng
doaj   +1 more source

Motor Cortex Response to Pleasant Odor Perception and Imagery: The Differential Role of Personality Dimensions and Imagery Ability

open access: yesFrontiers in Human Neuroscience, 2022
BackgroundNeuroimaging studies have shown a complex pattern of brain activation during perception of a pleasant odor and during its olfactory imagery. To date, little is known regarding changes in motor cortex excitability during these tasks.
Carmenrita Infortuna   +13 more
doaj   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

open access: yesAdvanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong   +12 more
wiley   +1 more source

Localization of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) expression in mouse brain: A new perspective on N-acylethanolamines as Neural Signaling Molecules [PDF]

open access: yes, 2008
The definitive version is available at www3.interscience.wiley ...
Cravatt, BF   +3 more
core  

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