Results 21 to 30 of about 762 (132)

Pretreatment with different doses of oliceridine attenuates etomidate-induced myoclonus during painless gastroscopy: a randomized controlled trial [PDF]

Frontiers in Pharmacology
BackgroundEtomidate is commonly used for sedation during gastroscopy but is associated with a high incidence of myoclonus. This study evaluated the effectiveness of oliceridine pretreatment in reducing etomidate-induced myoclonus.MethodsIn this ...
Yingchuan Lin, Yun Dai, Weifeng Huang, Huaijian Zhang, Bin Yang   +4 more
doaj   +2 more sources

Safety and Efficacy of Oliceridine Combined with Propofol for Painless Gastroscopy: A Single-Center, Randomized, Parallel Controlled Clinical Trial [PDF]

Drug Design, Development and Therapy
Xuping Hu, Chunyuan Yang, Jun Li, Fuping Wang, Hongjiang You, Changchun Chen, Leyu JiangDepartment of Anesthesiology, Dazhou Central Hospital, Dazhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Leyu ...
Hu X, Yang C, Li J, Wang F, You H, Chen C, Jiang L   +6 more
doaj   +2 more sources

Tolerability of different doses of oliceridine versus traditional opioids in acute pain management: a systematic review and meta-analysis

Scientific Reports
This study aims to deliver a systematic review and meta-analysis to scrutinize the tolerability of different doses of oliceridine in acute pain patients. A comprehensive search was carried out in essential databases (PubMed, Embase, Cochrane Library, and
Yulin Liu
exaly   +2 more sources

Establishing the Median and 95% Effective Doses of Oliceridine for Immediate Post-Surgical Analgesia Following Laparoscopic Cholecystectomy: A Double-Blind, Sequential Dose-Finding Study [PDF]

Drug Design, Development and Therapy
Xianghua Cao,1,2,* Huiling Xiao,1,2,* Haoran Yan,1,2,* Yujiao Wei,1,2 Qiting Wen,1,2 Zhijian Zhang,1,2 Guizhen Xu,1,2 Binbin Xu,1,2 Jian Chen,1,2 Xueping Li1,2 1Department of Anesthesiology, Dongguan Tungwah Hospital, Dongguan, People’s ...
Cao X, Xiao H, Yan H, Wei Y, Wen Q, Zhang Z, Xu G, Xu B, Chen J, Li X   +9 more
doaj   +1 more source

Oliceridine effectively attenuates fentanyl-induced cough during general anesthesia induction [PDF]

Frontiers in Medicine
ObjectiveFentanyl-induced cough (FIC) is a common adverse event during anesthesia induction with a high incidence and may result in serious clinical complications.
Ru-Yi Xing, Wen-Yi Gong, Chen-Guang Li, Ilyar Mamtili, Shuang-Xiong Zhu, Wen-Jun Zhou, Bing-Xing Li, Jie Cao, Xiao-Fang Yue, Kun Fan   +9 more
doaj   +2 more sources

Oliceridine in the Prevention of Catheter-Related Bladder Discomfort: A Single-Center, Randomized, Double-Blind, Prospective Trial [PDF]

Drug Design, Development and Therapy
Rong-Juan Jiang,1 Shu Gao,1,2 Zhen Yang,3 Xue-Yong Bin,1,2 Lu Cheng,1,2 Shao-Xing Liu1 1Department of Anesthesiology, West China School of Medicine, Sichuan University, Sichuan University Affiliated Chengdu Second People’s Hospital, Chengdu Second People’
Jiang RJ, Gao S, Yang Z, Bin XY, Cheng L, Liu SX   +5 more
doaj   +2 more sources

Comparison of hemodynamic responses to endotracheal intubation with oliceridine and sufentanil during induction: a randomized controlled trial [PDF]

BMC Anesthesiology
Background Oliceridine, a G-protein-biased μ-opioid receptor agonist, offers a potential alternative to conventional opioids by reducing adverse effects. However, its efficacy in attenuating the hemodynamic response to endotracheal intubation compared to
Yu Zhang, Yuanyuan Li, Lei Li, Yan Gao, Xin Zhang, Shengzhe Shi, Yujuan Zheng, Junhong Yang, Yaowu Bai   +8 more
doaj   +2 more sources

A Comparison of Oliceridine versus Sufentanil for Patient-Controlled Analgesia After Total Knee Arthroplasty in Elderly Patients: A Double-Blinded Randomized Controlled Study [PDF]

Drug Design, Development and Therapy
Xi Liu,1,* Suna Wang,2,* Xiaoxiao Chen,1,* Yuanyuan Tian,1 Junli Sun,1 Aizhong Wang,1 Qi Li,1 Hui Zhang1 1Department of Anesthesiology, Shanghai Sixth People’s Hospital Affiliated with Shanghai Jiao Tong University School of ...
Liu X, Wang S, Chen X, Tian Y, Sun J, Wang A, Li Q, Zhang H   +7 more
doaj   +2 more sources

Effect of oliceridine on hypoxia during sedated hysteroscopy: a Phase 4 randomized clinical trial [PDF]

Communications Medicine
Background Hypoxia is a common complication in hysteroscopic surgery under sedation with conventional opioids. Oliceridine, a novel G protein-biased μ-opioid receptor agonist, provides effective analgesia with fewer opioid-related adverse events, but its
Ye Liu, Mingshu Tao, Biran Dai, Xia Yin, Xinyu Gu, Jie Xiao, Jun-Li Cao, Weifeng Yu, Liqun Yang, Song Zhang   +9 more
doaj   +2 more sources

Effect of oliceridine versus morphine on the quality of early recovery after thoracoscopic surgery: a randomized, controlled clinical trial [PDF]

BMC Anesthesiology
Background Thoracic surgery is frequently accompanied by severe pain. Although opioids remain the primary choice for effective analgesia in acute moderate-to-severe pain, their use is limited by adverse effects.
Xueqing Na, Ying Chen, Xin Liu, Jian Yang, Miao Tan, Yun Zhou, Man Shi, Jie Ouyang, Yongyu Si   +8 more
doaj   +2 more sources