Results 1 to 10 of about 762 (132)

Determination of the median effective dose (ED₅₀) of oliceridine combined with propofol for inhibiting gastroscope insertion responses in adult patients undergoing painless gastroscopy [PDF]

Frontiers in Medicine
BackgroundPropofol is the most frequently administered intravenous anesthetic in painless gastroscopy. Oliceridine, a novel μ-opioid receptor agonist, exhibits analgesic effects while reducing adverse reactions.
Xiaojing Zhang, Weimin Qin, Xinying Zhang, Wenbo Liang, Zhiqiang Ren, Qing Ma, Li Zhou, Longbin Zheng, Longbin Zheng   +8 more
doaj   +3 more sources

Effect of vaginal delivery history on oliceridine ED₅₀ combined with propofol during painless hysteroscopy: a modified Dixon sequential study [PDF]

Frontiers in Medicine
ObjectiveTo determine the median effective dose (ED50) of oliceridine combined with propofol for inhibiting movement response during hysteroscopy in patients with versus without a history of vaginal delivery.MethodsPatients scheduled for hysteroscopy who
Xinyang Zhang, Xiaoyu Gu, Jinfeng Cao, Jianlong Du, Liuqin Jiang   +4 more
doaj   +3 more sources

Determination of the effective dose of oliceridine combined with propofol using the modified Dixon’s up-and-down method in painless gastroscopy [PDF]

Frontiers in Pharmacology
ObjectiveTo investigate the median effective dose (ED50) and 95% effective dose (ED95) of oliceridine combined with propofol for painless gastroscopy in adults.MethodsPatients underwent painless gastroscopy were divided to male and female cohorts.
Jinfeng Cao, Xiaoyu Gu, Xinyang Zhang, Yao Cheng, Liuqin Jiang   +4 more
exaly   +4 more sources

Oliceridine versus sufentanil: a systematic review and meta-analysis of postoperative nausea and vomiting [PDF]

BMC Anesthesiology
Background Oliceridine is a novel µ-opioid receptor agonist designed to reduce opioid-related adverse events while maintaining effective analgesia. However, randomized controlled trials comparing oliceridine with conventional opioids, such as sufentanil,
Jixiang Wan, Jiaman Li, Li Liao, Chunyang Shao, Li Zhao, Fang-Jun Wang   +5 more
doaj   +2 more sources

A two-phase randomized study of oliceridine versus sufentanil for gastrointestinal endoscopy [PDF]

Frontiers in Pharmacology
BackgroundOliceridine is a novel G protein-biased μ-opioid receptor (MOR) agonist. It provides analgesic effects and reduces opioid-related adverse events (ORAEs). It has shown good efficacy in acute pain management.
Dengyun Hu, Dengyun Hu, Panpan Ding, Junjie Liu, Kaixiang Cao, Kaixiang Cao, Hongyun Bi, Hongyun Bi, Jinfeng Bao, Linghui Huang, Tingting Zhang, Xin Wang, Xin Wang   +12 more
doaj   +2 more sources

Oliceridine used for patient-controlled analgesia on postoperative quality of recovery in patients undergoing laparoscopic gynecological tumour resection: a randomized clinical trial [PDF]

Annals of Medicine
Background Oliceridine, a novel biased μ-opioid receptor agonist, is widely used perioperatively, yet limited data exists regarding its impact on postoperative quality of recovery.
Chunyan Li, Xinna Luo, Yanli Du, Jinrui Wei, Yan Qiu, Wanyun Ge, Fei Lin   +6 more
doaj   +2 more sources

Effect of Oliceridine on the Acute Postoperative Pain Management After Elective Cesarean Delivery: A Randomized Non-Inferiority Trial [PDF]

Drug Design, Development and Therapy
Jing Jiang,1,* Guanghua Yuan,1,* Yuhui Shi,1,* Zhou Zhou,1 Xinxin Wang,1 Xiaoqiao Sang,1 Xiaobao Zhang1,21Department of Anesthesiology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, Jiangsu, People’
Jiang J, Yuan G, Shi Y, Zhou Z, Wang X, Sang X, Zhang X   +6 more
doaj   +2 more sources

Efficacy and safety of oliceridine in daytime hysteroscopic polypectomy: a randomized, double-blind, single-center controlled trial [PDF]

Frontiers in Medicine
BackgroundThis study aimed to compare the effects of oliceridine, fentanyl, and sufentanil on early recovery and perioperative safety during hysteroscopic polypectomy.MethodsA single-center, double-blind, randomized controlled trial enrolled 92 patients ...
Yuan Wang, Yufeng Qiu, Lan Wang, Jiaming Kang, Wenbin Zhang, Pragyanshu Khare, Xinnan Song   +6 more
doaj   +2 more sources

The Satisfactory Analgesia and Minimal Emesis of Elderly Patients After Thoracoscopic Lung Surgery: Oliceridine versus Sufentanil in a Randomized Controlled Trial [PDF]

Drug Design, Development and Therapy
Yongliang Cai, Yihao Jiang, Qingwei Zhang, Jianjun Yang, Zhongyun Wang,* Heliang Sun* Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210000, People’s ...
Cai Y, Jiang Y, Zhang Q, Yang J, Wang Z, Sun H   +5 more
doaj   +2 more sources

Median effective dose and 95% effective dose of oliceridine combined with ciprofol for painless gastroscopy: a dose-finding study based on Dixon’s up-and-down method [PDF]

Frontiers in Pharmacology
ObjectiveTo determine the median effective dose and estimate 95% effective dose of oliceridine combined with ciprofol for suppressing gastroscope insertion responses, stratified by sex.MethodsThis prospective, sex-stratified trial enrolled patients ...
Xikun Sun, Pei Song, Bin Zou, Yimeng Zhuang, Xiaohang Han, Jianyu Zu, Yugang Diao   +6 more
doaj   +2 more sources