Results 1 to 10 of about 699 (156)

A two-phase randomized study of oliceridine versus sufentanil for gastrointestinal endoscopy [PDF]

Frontiers in Pharmacology
BackgroundOliceridine is a novel G protein-biased μ-opioid receptor (MOR) agonist. It provides analgesic effects and reduces opioid-related adverse events (ORAEs). It has shown good efficacy in acute pain management.
Dengyun Hu, Dengyun Hu, Panpan Ding, Junjie Liu, Kaixiang Cao, Kaixiang Cao, Hongyun Bi, Hongyun Bi, Jinfeng Bao, Linghui Huang, Tingting Zhang, Xin Wang, Xin Wang   +12 more
doaj   +2 more sources

Efficacy and safety of oliceridine in daytime hysteroscopic polypectomy: a randomized, double-blind, single-center controlled trial [PDF]

Frontiers in Medicine
BackgroundThis study aimed to compare the effects of oliceridine, fentanyl, and sufentanil on early recovery and perioperative safety during hysteroscopic polypectomy.MethodsA single-center, double-blind, randomized controlled trial enrolled 92 patients ...
Yuan Wang, Yufeng Qiu, Lan Wang, Jiaming Kang, Wenbin Zhang, Pragyanshu Khare, Xinnan Song   +6 more
doaj   +2 more sources

The Satisfactory Analgesia and Minimal Emesis of Elderly Patients After Thoracoscopic Lung Surgery: Oliceridine versus Sufentanil in a Randomized Controlled Trial [PDF]

Drug Design, Development and Therapy
Yongliang Cai, Yihao Jiang, Qingwei Zhang, Jianjun Yang, Zhongyun Wang,* Heliang Sun* Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210000, People’s ...
Cai Y, Jiang Y, Zhang Q, Yang J, Wang Z, Sun H   +5 more
doaj   +2 more sources

Effect of Oliceridine Fumarate for Patient-Controlled Intravenous Analgesia on Gastrointestinal Function in Laparoscopic Radical Gastrectomy Surgery: A Randomized, Double-Blind, Controlled Trial [PDF]

Drug Design, Development and Therapy
Chen Wang,1,2,* Wang-Dong Xu,1,2,* Xin-Lei Lu,2 Wei-Ping Lei,2 Jian-Liang Sun,1,2 Ya-Qin Huang2 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People’s Hospital, Hangzhou, Zhejiang, 310006 ...
Wang C, Xu WD, Lu XL, Lei WP, Sun JL, Huang YQ   +5 more
doaj   +2 more sources

Pretreatment with different doses of oliceridine attenuates etomidate-induced myoclonus during painless gastroscopy: a randomized controlled trial [PDF]

Frontiers in Pharmacology
BackgroundEtomidate is commonly used for sedation during gastroscopy but is associated with a high incidence of myoclonus. This study evaluated the effectiveness of oliceridine pretreatment in reducing etomidate-induced myoclonus.MethodsIn this ...
Yingchuan Lin, Yun Dai, Weifeng Huang, Huaijian Zhang, Bin Yang   +4 more
doaj   +2 more sources

Efficacy and safety of Oliceridine versus Sufentanil in postoperative analgesia for burn skin grafting: a machine learning and SHAP-based cohort study [PDF]

Frontiers in Medicine
BackgroundBalancing profound analgesia with the minimization of opioid-related adverse events, particularly postoperative nausea and vomiting (PONV), remains challenging in burn surgery.
Ye Tian, Yun Zhang, Danshi Feng, Hongying Wang, Zihuan Ma   +4 more
doaj   +2 more sources

Nausea and vomiting as adverse events of oliceridine: a systematic review and meta-analysis of randomized controlled trials [PDF]

Frontiers in Pharmacology
BackgroundPostoperative nausea and vomiting (PONV) continue to be some of the most common and troublesome complications following anesthesia. Oliceridine, a G protein-biased µ-opioid receptor agonist, has the potential to provide effective pain relief ...
Jinfang Zeng, Shu Yang, Shu Yang, Jinjin Jian, Minmin Zhu   +4 more
doaj   +2 more sources

Impact of oliceridine versus sufentanil on postoperative nausea and vomiting in patients undergoing thyroid surgery: a prospective, double-blind, randomized controlled trial [PDF]

Annals of Medicine
Purpose Postoperative nausea and vomiting (PONV) is a common complication following thyroid surgery, often exacerbated by opioid use. Oliceridine, a novel G protein-biased μ-opioid receptor agonist, may reduce opioid-related adverse events.
Feng Liu, Wang Shen, Dan Su, Zhaoming Guan, Yi Zhang, Siyu Li, Qisong Yuan, Yupeng Zhao, Jixiong Sun, Hongwei Fang, Longqiu Yang   +10 more
doaj   +2 more sources

Oliceridine effectively attenuates fentanyl-induced cough during general anesthesia induction [PDF]

Frontiers in Medicine
ObjectiveFentanyl-induced cough (FIC) is a common adverse event during anesthesia induction with a high incidence and may result in serious clinical complications.
Ru-Yi Xing, Wen-Yi Gong, Chen-Guang Li, Ilyar Mamtili, Shuang-Xiong Zhu, Wen-Jun Zhou, Bing-Xing Li, Jie Cao, Xiao-Fang Yue, Kun Fan   +9 more
doaj   +2 more sources

Effect of Oliceridine Combined with Sufentanil on Patient-Controlled Intravenous Analgesia in Elderly Patients After Laparoscopic Radical Resection of Rectal Cancer: A Prospective Randomized Controlled Study [PDF]

Drug Design, Development and Therapy
Yifu Tian, Jiarui Hu, Haitao Pan, Guang Bai, Zhao Zhang, Peng Zhang Department of Anesthesiology, Tianjin Cancer Hospital Airport Hospital, National Clinical Research Center for Cancer, Airport Economic Zone, Tianjin, 300308, People’s Repulic of ...
Tian Y, Hu J, Pan H, Bai G, Zhang Z, Zhang P   +5 more
doaj   +2 more sources