Results 111 to 120 of about 63,056 (297)

Ubiquitination in cancer: mechanisms and therapeutic opportunities

open access: yesCancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu   +7 more
wiley   +1 more source

Effect of Glucose Deprivation on Sulfatide Synthesis and Oligodendrocytes in Cultured Brain Cells of Newborn Mice [PDF]

open access: bronze, 1981
K Zuppinger   +6 more
openalex   +1 more source

Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin   +5 more
wiley   +1 more source

A head start: The relationship of placental factors to craniofacial and brain development

open access: yesDevelopmental Dynamics, EarlyView.
Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver   +2 more
wiley   +1 more source

The endocannabinoid system regulates both ependymoglial and neuronal cell responses to a tail amputation in the axolotl

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino   +3 more
wiley   +1 more source

Initiation of CNS Myelination in the Optic Nerve Is Dependent on Axon Caliber

open access: yesCell Reports, 2018
Summary: Emerging evidence suggests that neuronal signaling is important for oligodendrocyte myelination; however, the necessity of this signaling during development is unclear.
Sonia R. Mayoral   +3 more
doaj  

Plasticity in the adult human oligodendrocyte lineage [PDF]

open access: hybrid, 1994
Nitin Gogate   +9 more
openalex   +1 more source

Alpha‐Lipoic Acid Alleviates Isoflurane‐Induced Cognitive Dysfunction in Juvenile Mice by Activating Peroxisome Proliferator Activated Receptor Gamma Coactivator ‐1 Alpha

open access: yesFood Frontiers, EarlyView.
Alpha‐lipoic acid (ALA) plays a significant role in alleviating isoflurane‐induced cognitive dysfunction in juvenile mice by activating PGC‐1α, which improves mitochondrial function and energy metabolism in astrocytes. As a potent antioxidant, ALA is commonly found in foods like spinach, broccoli, and yeast, and its supplementation may offer ...
Xingkai Zhao   +4 more
wiley   +1 more source

PDGF and FGF2 pathways regulate distinct oligodendrocyte lineage responses in experimental demyelination with spontaneous remyelination

open access: yesNeurobiology of Disease, 2005
Repair of myelin damage in the adult CNS requires oligodendrocyte progenitor (OP) proliferation and subsequent differentiation into remyelinating oligodendrocytes.
Joshua C. Murtie   +4 more
doaj  

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