Results 121 to 130 of about 105,413 (339)
Advanced Science, EarlyView.This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song +15 more
wiley +1 more source
The Axon-Myelin Unit in Development and Degenerative Disease
Frontiers in Neuroscience, 2018 Axons are electrically excitable, cable-like neuronal processes that relay information between neurons within the nervous system and between neurons and peripheral target tissues.
Ruth M. Stassart +5 more
doaj +1 more source
The Genetic Signature of Perineuronal Oligodendrocytes [PDF]
, 2008 Oligodendrocytes in the central nervous system can be categorized as precursors, myelin-forming, and non-myelinating perineuronal cells. The function of perineuronal oligodendrocytes is unknown; it was proposed that following injury, they may remyelinate
Dragan Maric +5 more
core +1 more source
Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems
Advanced Science, EarlyView.Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar +10 more
wiley +1 more source
Frontiers in Psychiatry, 2016 Bipolar disorder (BD) is a major psychiatric illness with a chronic recurrent course, ranked among the worldwide leading disabling diseases. Its pathophysiology is still not completely understood, and findings are still inconclusive, though a great ...
MARCELLA eBELLANI +7 more
doaj +1 more source
A rapid silver impregnation technique for oligodendrocytes, microglia, and astrocytes. [PDF]
, 1971 T. Scott
openalex +1 more source
Development of glial restricted human neural stem cells for oligodendrocyte differentiation in vitro and in vivo. [PDF]
, 2019 In this study, we have developed highly expandable neural stem cells (NSCs) from HESCs and iPSCs that artificially express the oligodendrocyte (OL) specific transcription factor gene Zfp488. This is enough to restrict them to an exclusive oligodendrocyte
Biswas, Sangita +4 more
core +1 more source
Delayed Transplantation of Neural Stem Cells Improves Initial Graft Survival after Stroke
Advanced Science, EarlyView.Delayed transplantation of human iPSC‐derived neural progenitor cells (NPCs) enhances graft survival, proliferation, and axonal sprouting after stroke. Using bioluminescence imaging and histology in a mouse model of stroke, it is shown that NPC delivery at 7 days post‐stroke is more effective than acute transplantation, highlighting the importance of ...
Rebecca Z Weber +6 more
wiley +1 more source
Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
Advanced Science, EarlyView.This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu +9 more
wiley +1 more source
Concepts for regulation of axon integrity by enwrapping glia
Frontiers in Cellular Neuroscience, 2013 Long axons and their enwrapping glia (Schwann cells and oligodendrocytes) form a unique compound structure that serves as conduit for transport of electric and chemical information in the nervous system.
Bogdan eBeirowski
doaj +1 more source