Results 191 to 200 of about 100,602 (348)
Plasticity in the adult human oligodendrocyte lineage [PDF]
Nitin Gogate+9 more
openalex +1 more source
Th1 pro-inflammatory cytokines, i.e., TNF-α and IFN-γ, in combination are known to induce cell death in several cell types, including oligodendrocytes, but the mechanism of their synergistic cytotoxicity is unclear.
Maria Podbielska+6 more
doaj
Neuromodulin (GAP43): a neuronal protein kinase C substrate is also present in 0-2A glial cell lineage. Characterization of neuromodulin in secondary cultures of oligodendrocytes and comparison with the neuronal antigen. [PDF]
Jean-Christophe Deloulme+5 more
openalex +1 more source
Antibody neutralization of neurite growth inhibitors from oligodendrocytes results in expanded pattern of postnatally sprouting retinocollicular axons [PDF]
Josef P. Kapfhammer+2 more
openalex +1 more source
Comprehensive analysis of cortical astrocyte gene expression across the lifespan. Profiling dynamic changes of key astrocyte genes reveals functional shifts. Astrocytes contribute to gene‐length‐dependent transcription decline in the aging brain. ABSTRACT Astrocytes are the most abundant glial cell type in the central nervous system (CNS).
Xiaoran Wei+2 more
wiley +1 more source
Nogo‐A oligodendrocytes expression emerges at perilesional regions over time and suggests an extended therapeutical window for anti‐Nogo‐A pathway trageting interventrions beyond four weeks in patients after spinal cord injury. Abstract The myelin‐associated inhibitor Nogo‐A (Reticulon 4, RTN4) restricts axonal outgrowth, plasticity, and neural ...
Carmen Schwaiger+9 more
wiley +1 more source
In the presence of dexamethasone, gamma interferon induces rat oligodendrocytes to express major histocompatibility complex class II molecules. [PDF]
K Bergsteindottir+3 more
openalex +1 more source
Ablation of autophagy in oligodendrocytes reveals increased PLP expression, myelin abnormalities, axon degeneration, and increased microglia activation in aged mice. The aged mice exhibit marked deficits in learning and memory tasks. ABSTRACT The aging central nervous system (CNS) is often marked by myelin degeneration, yet the underlying mechanisms ...
Niki Ktena+8 more
wiley +1 more source
Schematic depicting characterization of pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in neurodegenerative diseases. Abstract Accumulation of pathological tau aggregates is a prominent feature in tauopathies that leads during the course of the diseases to neuronal dysfunction before and cell death after ...
Mauro Montalbano+4 more
wiley +1 more source