Results 221 to 230 of about 63,056 (297)

Quantitative insight into proliferation and differentiation of oligodendrocyte type 2 astrocyte progenitor cells in vitro

, 1998
Andrej Yu. Yakovlev, Kenneth M. Boucher, Margot Mayer‐Pröschel, Mark Noble   +3 more
openalex   +1 more source

Nimodipine reduces microglial activation in vitro as evidenced by morphological phenotype, phagocytic activity and high‐throughput RNA sequencing

British Journal of Pharmacology, EarlyView.
Background and Purpose Nimodipine, an L‐type voltage‐gated calcium channel blocker, is an approved cerebral vasorelaxant. We hypothesized that nimodipine attenuates the pro‐inflammatory shift in microglial phenotypes. Here, we analysed the effects of nimodipine on morphological and functional microglial phenotypes as well as their transcriptomic ...
István Pesti, Valentin Varga, Erda Qorri, Rita Frank, Diana Kata, Krisztián Vinga, Péter Archibald Szarvas, Ákos Menyhárt, Károly Gulya, Ferenc Bari, Eszter Farkas   +10 more
wiley   +1 more source

The impact of autoimmune comorbidities on the onset attack recovery in adults with AQP4-NMOSD and MOGAD. [PDF]

J Neurol
Samadzadeh S, Chan F, Francis A, Sani L, Paul F, Asgari N, Leite MI, Geraldes R, Palace J.   +8 more
europepmc   +1 more source

E587 antigen is upregulated by goldfish oligodendrocytes after optic nerve lesion and supports retinal axon regeneration

, 1998
Richard Ankerhold, Christian A. Leppert, Martin Bastmeyer, Claudia A. O. Stuermer   +3 more
openalex   +2 more sources

Pharmacological evaluation of non‐nucleotide purine derivatives as P2X7 antagonists for the treatment of neuroinflammation in traumatic brain injury

British Journal of Pharmacology, EarlyView.
Background and purpose Traumatic brain injury (TBI) is considered to be a leading cause of mortality and disability worldwide. After TBI, innate immunity is rapidly activated in response to damage‐associated molecular patterns, such as ATP release, recognised by P2X7 receptors.
Inés Valencia, Andrea Pastor‐Martínez, Céline Decouty‐Pérez, Ana Belen Lopez‐Rodriguez, María Álvarez‐Rubal, Eva Ramos, Francesco Calzaferri, Jorge Zamorano‐Fernández, Javier Giner‐García, Alexis J. Palpán‐Flores, Víctor Rodríguez‐Domínguez, Javier Rodríguez de Cía, Borja J. Hernández‐García, Alejandro Romero, Cristóbal de los Ríos, Javier Egea   +15 more
wiley   +1 more source

Synergistic Effects of Olfactory Ecto-Mesenchymal Stem Cell Supernatant and Ellagic Acid on Demyelination and Glial Modulation in a Chronic Multiple Sclerosis Model. [PDF]

Cell Mol Neurobiol
Tahmasebi F, Asl ER, Faghihi F, Bolandi N, Barati S.   +4 more
europepmc   +1 more source

Effect of time to initiation and dose of methylprednisolone on outcome in multiple sclerosis‐related optic neuritis

Clinical and Experimental Neuroimmunology, EarlyView.
Abstract Objectives It is known that the benefit of intravenous methylprednisolone (IVMP) in multiple sclerosis‐related optic neuritis (MS‐ON) is limited to an accelerated recovery. We aimed to evaluate the impact of time from symptoms onset to IVMP initiation and of IVMP dose on visual recovery among people with MS‐ON.
Hadar Gilad, Josepha Horowitz, Sivan Bloch, Daniel Golan   +3 more
wiley   +1 more source

Astrocyte and oligodendrocyte pathology in Alzheimer's disease. [PDF]

Neurotherapeutics
Ziar R, Tesar PJ, Clayton BLL.
europepmc   +1 more source

Fate of oligodendrocytes during retinal axon degeneration and regeneration in the goldfish visual pathway

, 1999
Richard Ankerhold, Claudia A. O. Stuermer   +1 more
openalex   +2 more sources

Aging and Multiple Sclerosis

Clinical and Experimental Neuroimmunology, EarlyView.
ABSTRACT Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease. While typically diagnosed in young adults, late‐onset MS (LOMS, onset > 50 years) is becoming increasingly recognized, presenting with distinct features such as higher rates of progressive onset and motor symptoms.
Takuya Matsushita
wiley   +1 more source