The Fragile X Messenger Ribonucleoprotein 1 Regulates the Morphology and Maturation of Human and Rat Oligodendrocytes. [PDF]
Ramesh V+15 more
europepmc +1 more source
Targeting gut microbiota as a therapeutic approach for neurodegenerative diseases
The abstract depicts the gut‐brain axis, illustrating the bidirectional communication between the gastrointestinal tract and the central nervous system. Probiotics can induce the production of neurotrophins, neurotransmitters, SCFAs, and contribute to increased antioxidant levels, which can benefit brain health. In contrast, antibiotics can disrupt the
Tobiloba S. Olajide+1 more
wiley +1 more source
Correction to: Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age-dependent Manner. [PDF]
Chen H+10 more
europepmc +1 more source
A Role in Migration for the αvβ1 Integrin Expressed on Oligodendrocyte Precursors [PDF]
R. Milner+3 more
openalex +1 more source
The role of gut microbiota‐derived metabolites in neuroinflammation
Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley +1 more source
Astrocyte and oligodendrocyte pathology in Alzheimer's disease. [PDF]
Ziar R, Tesar PJ, Clayton BLL.
europepmc +1 more source
Optic Nerve Sheath Meningiomas in Children: Diagnostic Challenges Based on a Case Series
ABSTRACT The diagnosis of optic nerve sheath meningiomas (ONSM) in children and teenagers remains challenging despite advances in high‐quality imaging. We identified seven children diagnosed with ONSM in four tertiary paediatric oncology centres in the United Kingdom.
Deysha Ratnasingham+15 more
wiley +1 more source
MRI signatures of cortical microstructure in human development align with oligodendrocyte cell-type expression. [PDF]
Genc S+8 more
europepmc +1 more source
Microglial Drivers of Alzheimer's Disease Pathology: An Evolution of Diverse Participating States
ABSTRACT Microglia, the resident immune‐competent cells of the brain, become dysfunctional in Alzheimer's disease (AD), and their aberrant immune responses contribute to the accumulation of pathological proteins and neuronal injury. Genetic studies implicate microglia in the development of AD, prompting interest in developing immunomodulatory therapies
Madison K. Kuhn, Elizabeth A. Proctor
wiley +1 more source
Single-cell sequencing reveals that AK5 inhibits apoptosis in AD oligodendrocytes by regulating the AMPK signaling pathway. [PDF]
Yang S+7 more
europepmc +1 more source