Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling
Neuron, 2013 K. Young +7 more
semanticscholar +1 more source
Mathematical Modeling of Neuroinflammation in Neurodegenerative Diseases
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Age‐related neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD) and Parkinson's disease (PD) are an increasing public health concern. Whereas the pathology of these diseases is complex, chronic central inflammation, or neuroinflammation, is commonly observed across many neurodegenerative diseases ...
Alex Foster‐Powell +4 more
wiley +1 more source
Valproate-vitamin E co-treatment preserved cortico-callosal white matter integrities in cypermethrin co-exposed pentylene tetrazole induced seizure. [PDF]
BMC NeurosciImam A +4 more
europepmc +1 more source
Mitochondrial dynamics in autoimmune diseases
Rheumatology &Autoimmunity, EarlyView.Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma +5 more
wiley +1 more source
Integrative transcriptomic analysis reveals oligodendrocyte lineage switching in multiple sclerosis. [PDF]
Life Sci AllianceYan ZZ +5 more
europepmc +1 more source
Secretome Profiling in Axon Regeneration: Emerging Techniques and Therapeutic Translation
Sensory Neuroscience, EarlyView.ABSTRACT The secretome refers to the in vivo ensemble of molecular entities that are found in interstitial spaces. It is then the mere secreted products of the cells, as all biomolecules in the interstitial cellular spaces also undergo modifications. The fractionated secretome may hold potential as a cell‐free therapy option due to its role in tissue ...
Maria D. Cabrera +3 more
wiley +1 more source
Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury
Small Science, EarlyView.Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li +5 more
wiley +1 more source
Canonical and non-canonical roles of oligodendrocyte precursor cells in mental disorders. [PDF]
Npj Ment Health ResPoggi G +5 more
europepmc +1 more source
Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons
Small Science, EarlyView.This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong +4 more
wiley +1 more source
Management and burden of disease in people with myelin oligodendrocyte glycoprotein antibody-associated disease: data from an international, cross-sectional survey. [PDF]
J NeurolPaul F +6 more
europepmc +1 more source