Results 271 to 280 of about 63,056 (297)

Oligodendrocytic Gliomatosis Cerebri

Acta Neurochirurgica, 2000
We describe a very unusual case of gliomatosis cerebri (GC) with oligodendrocytic differentiation. A 65-year-old man presented with a convulsive seizure. Magnetic resonance (MR) documented diffuse enlargement of cerebral hemispheres, brainstem, and right cerebellar hemisphere.
Tancredi, A, Mangiola, A, Guiducci, A, Peciarolo, A, Ottaviano, P   +4 more
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Oligodendrocyte differentiation

2016
In the nervous system, axons transmit information in the form of electrical impulses over long distances. The speed of impulse conduction is enhanced by myelin, a lipid-rich membrane that wraps around axons. Myelin also is required for the long-term health of axons by providing metabolic support.
B. Appel, E.S. Mathews
openaire   +3 more sources

Diversity of oligodendrocytes and their progenitors

Current Opinion in Neurobiology, 2017
The established function of oligodendrocytes and their progenitors is to drive the cellular events of myelination, a highly diversified process necessary to match the needs of various neuronal subtypes and networks. The morphological and molecular heterogeneity of oligodendrocytes and their progenitors point to functions beyond establishing saltatory ...
Dimou, Leda, Simons, Mikael
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The Role of Oligodendrocytes and Oligodendrocyte Progenitors in cns Remyelination

1999
Remyelination enables restoration of saltatory conduction and a return of normal function lost during demyelination. Unfortunately, remyelination is often incomplete in the adult human central nervous system (CNS) and this failure of remyelination is one of the main reasons for clinical deficits in demyelinating disease. An understanding of the failure
Hans S. Keirstead, William F. Blakemore
openaire   +3 more sources

Oligodendrocytes and Alzheimer's disease

International Journal of Neuroscience, 2015
Extensive evidence has indicated that the breakdown of myelin is associated with Alzheimer's disease (AD) since the vulnerability of oligodendrocytes under Alzheimer's pathology easily induces the myelin breakdown and the loss of the myelin sheath which might be the initiating step in the changes of the earliest stage of AD prior to appearance of ...
Zhiyou Cai, Ming Xiao
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Immunobiology of the oligodendrocyte

2010
INTRODUCTION Oligodendrocytes, as the myelin-producing cells of the central nervous system (CNS), are exactly what their Greek-derived name “oligodendroglia” suggests: they, alongside astrocytes, the non-neural microglia and ependymal cells, have been characterized as the “glue” that holds together the intricate apparatus of our brain.
Hans-Peter Hartung, Patrick Küry, David Kremer, Orhan Aktas   +3 more
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Regulation of oligodendrocyte development

Molecular Neurobiology, 1998
Oligodendrocytes are the cells responsible for the formation of myelin in the central nervous system. Recent studies demonstrated that cells of the oligodendrocyte lineage initially arise in distinct regions of the ventricular zone during early development.
Diana M. Orentas, Robert H. Miller
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Oligodendrocyte origins

Trends in Neurosciences, 1996
In the adult vertebrate CNS, oligodendrocytes are ubiquitously distributed throughout white matter. By contrast, in the embryonic CNS, recent studies suggest that oligodendrocyte precursors arise in a discrete ventral location. Thus, local ventral environmental signals that contribute to the overall patterning of the CNS are likely to influence the ...
openaire   +2 more sources

Regulation of oligodendrocyte development

Microscopy Research and Technique, 2001
AbstractOligodendrocytes are myelinating cells in the central nervous system. Recent studies demonstrated that oligodendrocyte progenitor cells are generated from a restricted region in the ventricular zone. In the rodent spinal cord, progenitor cells appear from narrow and bilateral longitudinal columns in the ventral ventricular zone, and then ...
Kazuhiro Ikenaka, Tetsushi Kagawa, Tamaki Wada   +2 more
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Calcium signalling in oligodendrocytes [PDF]

Neurophysiology, 1995
Generation of calcium signal in mammalian oligodendrocytes is a result of two different mechanisms, namely: (i) transmembrane calcium influx via voltage-operated calcium channels, and (ii) calcium release from IP3-sensitive internal calcium stores.
Verkhratsky, A, Kettenmann, H, Kirischuk, S   +2 more
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