Results 41 to 50 of about 85,792 (299)

Myelin oligodendrocyte glycoprotein antibody-associated optic neuritis and myelitis in COVID-19: a case report and a review of the literature

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022
Background Our case explored the spectrum of autoimmune and infectious neurological complications of Coronavirus Disease 2019. In addition, we also reviewed and discussed clinical features, neuroimaging, CSF findings, and outcomes in patients with COVID ...
Mark A. Colantonio   +7 more
doaj   +1 more source

Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures

open access: yesFrontiers in Molecular Neuroscience, 2023
Combined antiretroviral therapy (cART) has greatly decreased mortality and morbidity among persons with HIV; however, neurologic impairments remain prevalent, in particular HIV-associated neurocognitive disorders (HANDs).
Hubert Monnerie   +6 more
doaj   +1 more source

Embracing oligodendrocyte diversity in the context of perinatal injury

open access: yesNeural Regeneration Research, 2017
Emerging evidence is fueling a new appreciation of oligodendrocyte diversity that is overturning the traditional view that oligodendrocytes are a homogenous cell population.
Jessie Newville   +2 more
doaj   +1 more source

Sleep and Oligodendrocyte Functions [PDF]

open access: yesCurrent Sleep Medicine Reports, 2015
Transcriptomic studies have revealed that the brains of sleeping and awake animals differ significantly at the molecular level, with hundreds of brain transcripts changing their expression across behavioral states. However, it was unclear how sleep affects specific cells types, such as oligodendrocytes, which make myelin in the healthy brain and in ...
openaire   +3 more sources

Perilipin-2 mediates ferroptosis in oligodendrocyte progenitor cells and myelin injury after ischemic stroke

open access: yesNeural Regeneration Research
Differentiation of oligodendrocyte progenitor cells into mature myelin-forming oligodendrocytes contributes to remyelination. Failure of remyelination due to oligodendrocyte progenitor cell death can result in severe nerve damage.
Jian Yang   +9 more
doaj   +1 more source

Oligodendrocytes: biology and pathology [PDF]

open access: yesActa Neuropathologica, 2009
Oligodendrocytes are the myelinating cells of the central nervous system (CNS). They are the end product of a cell lineage which has to undergo a complex and precisely timed program of proliferation, migration, differentiation, and myelination to finally produce the insulating sheath of axons.
Bradl, Monika, Lassmann, Hans
openaire   +2 more sources

Ramifications of microglial activation on oligodendrocytes in in vitro models of multiple sclerosis [PDF]

open access: yes, 2010
Oligodendrocytes are the principal target of immune attack in multiple sclerosis (MS), where the immune system attacks the myelin sheath, leading to oligodendrocyte demise, compromised axonal saltatory conduction and eventually neuronal degeneration ...
Sevastou, I.
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

NF-κB RelA regulates temporal oligodendrocyte differentiation in the postnatal brains

open access: yesFrontiers in Cellular Neuroscience
The NF-κB signaling pathway responds to a diverse range of cytokines and extracellular stresses, regulating immune responses, inflammation, cell proliferation, and cell death.
Kamonrapat Sompub   +6 more
doaj   +1 more source

Molecular mechanisms underlying Mash1 function in oligodendrogenesis [PDF]

open access: yes, 2010
Members of the basic helix-loop-helix (bHLH) proneural family of proteins, including Mash1, are crucial transcription factors (TFs) in neurogenesis. More recently, a role for Mash1 in the specification of oligodendrocyte precursor cells (OPCs) has been ...
Galiñanes García, L.
core  

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