Results 211 to 220 of about 113,519 (282)

Ganglioglioma in the spinal cord of a steer. [PDF]

J Vet Diagn Invest
Matto C, Rivero R, Woolard K, Uzal FA.
europepmc   +1 more source

Resistance‐exercise‐induced stress intervenes in TGF‐β signaling by cooperatively downregulating nuclear αB‐crystallin and SMAD4 in human skeletal muscle fibers

The FEBS Journal, EarlyView.
Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf, Cassandra Duda, Tihomir Kostov, Patrick Diel, Käthe Bersiner, Wilhelm Bloch, Sebastian Gehlert, Daniel Jacko   +7 more
wiley   +1 more source

Neuroglial Function and Hormonal Modulation in Neurodegenerative Diseases: The Influence of Sex Hormones. [PDF]

Cell Mol Neurobiol
Alhajeri MM, Abukhaled Y, Alkhanjari RR, Bassiouni W, Al-Ali H, Baig A, Sembaij SH, Al Muhairi FA, Dimassi Z, Hamdan H, Abd-Elrahman KS.   +10 more
europepmc   +1 more source

Directionality of longitudinal associations between frontostriatal structural connectivity and depressive symptoms in adolescent girls

Journal of Child Psychology and Psychiatry, EarlyView.
Background Individual differences in the structure and function of the frontostriatal reward network have been related to depression. However, there is a strong need for prospective, longitudinal studies aiming to understand the role of frontostriatal networks in depression in a developmental context.
Marjolein E.A. Barendse, Chris J. Machle, Rogier Kievit, Jennifer H. Pfeifer   +3 more
wiley   +1 more source

Glial cells in dementia: From cellular dysfunction to therapeutic frontiers. [PDF]

Cell Transplant
Jubair H.
europepmc   +1 more source

A Meta‐Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

Journal of Sleep Research, EarlyView.
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads, Megan H. Hagenauer, Jinglin Xiong, Erin Hernandez, Duy Manh Nguyen, Annaka Saffron, Elizabeth Flandreau, Stanley Watson Jr., Huda Akil   +8 more
wiley   +1 more source

Glial Cells as Key Mediators in the Pathophysiology of Neurodegenerative Diseases. [PDF]

Int J Mol Sci
Bogus K, Marchesi N, Campagnoli LIM, Pascale A, Pałasz A.   +4 more
europepmc   +1 more source

Alpha‐B‐crystallin immunohistochemistry: A sensitive but non‐specific marker for epileptogenic lesions

Brain Pathology, EarlyView.
Ekin Güney, Ilay Caliskan, Tara Saunders, Mercedes Paredes, Calixto‐Hope Lucas, Kanish Mirchia, Rufei Lu, Merryl Terry, Erika Cagampan, Melike Pekmezci, Andrew Bollen, Arie Perry, Cathryn R. Cadwell, Tarık Tihan   +13 more
wiley   +1 more source

Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

Psychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda, Michihiro Toritsuka, Hiroto Tamakoshi, Nakao Iwata, Manabu Makinodan   +4 more
wiley   +1 more source