Results 61 to 70 of about 88,496 (298)
Bisphenol A (BPA) is considered as one of the most extensively synthesized and used chemicals for industrial and consumer products. Previous investigations have established that exposure to BPA has been linked to developmental, reproductive ...
Santokh Gill, V. M. Ruvin Kumara
doaj +1 more source
Human oligodendrocytes in dissociated cell culture.
Human oligodendrocytes have been successfully maintained in cell cultures for 14 weeks using a modification of a method used previously for animal brain cell cultures.
Meier C, Kesselring J, Rihs F
core +1 more source
“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez +29 more
wiley +1 more source
Human oligodendroglial cells express low levels of C1 inhibitor and membrane cofactor protein mRNAs
Background Oligodendrocytes, neurons, astrocytes, microglia, and endothelial cells are capable of synthesizing complement inhibitor proteins. Oligodendrocytes are vulnerable to complement attack, which is particularly observed in multiple sclerosis. This
McGeer Patrick L +2 more
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Ube3a is expressed, but not apparently imprinted in cultured oligodendrocytes from AS animals.
WT upper panels, AS, lower panels. Left to Right: Myelin Basic Protein (MBP, a marker for oligodendrocytes), Ube3a and merge with DAPI. Ube3a is expressed throughout oligodendrocytes as shown by robust colocalization with MBP in both WT and AS ...
Robert P. Carson (421654) +2 more
core +1 more source
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab +19 more
wiley +1 more source
Investigation of Complement Activation and Cytokine Signatures in AQP4+ NMOSD, MOGAD, and MS
ABSTRACT Objective Aquaporin‐4‐IgG seropositive neuromyelitis optica spectrum disorder (AQP4+ NMOSD), myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), and multiple sclerosis (MS) are pathophysiologically distinct neuroinflammatory disorders. Complement activation is a major mechanism of injury in AQP4+ NMOSD, whereas its role in
Angeliki G. Filippatou +23 more
wiley +1 more source
Summary: Parkinson’s disease (PD) is a common neurodegenerative disease and is difficult to treat due to its elusive mechanisms. Recent studies have identified a striking association between oligodendrocytes and PD progression, yet how oligodendrocytes ...
Qiang Ma +13 more
doaj +1 more source
Can oligodendrocytes attached to myelin proliferate?
The uptake of thymidine by oligodendrocytes in the brains of adult mice was examined after the induction of cortical traumatic lesions in an attempt to determine whether mature oligodendrocytes actively attached to myelin sheaths were capable of ...
DA Bakker, SK Ludwin
core +1 more source
Objective The objective of this scoping review was to synthesize evidence on the proportion of individuals living with Sjögren's disease who experience central nervous system (CNS) manifestations. Methods We searched MEDLINE (via PubMed) and Embase from 1980 through January 29, 2026, and the ECRI Guidelines Trust from 2020 through January 29, 2026 ...
Arun Varadhachary +21 more
wiley +1 more source

