Results 81 to 90 of about 81,187 (302)
Dorsal spinal cord neuroepithelium generates astrocytes but not oligodendrocytes
, 1998 There is evidence that oligodendrocytes in the spinal cord are derived from a restricted part of the ventricular zone near the floor plate. An alternative view is that oligodendrocytes are generated from all parts of the ventricular zone.
Nigel P Pringle (16246637) +3 more
core +2 more sources
eLife, 2019 Neuron–glia communication contributes to the fine-tuning of synaptic functions. Oligodendrocytes near synapses detect and respond to neuronal activity, but their role in synapse development and plasticity remains largely unexplored.
Miae Jang +4 more
doaj +1 more source
Biomedicines, 2020 Oligodendrocytic injury by oxidative stress can lead to demyelination, contributing to neurodegeneration. We investigated the mechanisms by which an antioxidant, N-acetylcysteine (NAC), reduces oxidative stress in murine oligodendrocytes.
Jie Zhou +7 more
doaj +1 more source
Intrinsic resistance of oligodendrocytes to prion infection. [PDF]
, 2004 Within the CNS, the normal form of cellular prion protein (PrP(C)) is expressed on neurons, oligodendrocytes, and astrocytes. The contribution of these cell types to prion replication and pathogenesis is unclear.
Prinz, M +10 more
core +1 more source
Advanced Science, EarlyView.After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng +9 more
wiley +1 more source
Pharmaceuticals, 2020 We previously applied Systematic Evolution of Ligands by EXponential enrichment (SELEX) technology to identify myelin-specific DNA aptamers, using crude mouse central nervous system myelin as bait.
Mahboubeh Fereidan-Esfahani +7 more
doaj +1 more source
Differential expression and MAL-dependent targeting of the L-MAG and S-MAG isoforms to myelin membranes [PDF]
, 2003 Many degenerative diseases of the nervous system, including Multiple Sclerosis and peripheral neuropathies, are triggered by an impaired interaction between the axons and their surrounding myelin sheaths.
Erb, Michael
core +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
Advanced Science, EarlyView.We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Infestation of the lacrimal sac by Rhinosporidium seeberi: A clinicopathological case report
Indian Journal of Ophthalmology, 2013 Rhinosporidium seeberi , till recently known as a fungus, has been reclassified as a protistan parasite. It infects humans and many animal species. The authors describe a rare case of oculosporidiosis with involvement of the lacrimal sac exhibiting ...
Bipasha Mukherjee +3 more
doaj +1 more source
Ramifications of microglial activation on oligodendrocytes in in vitro models of multiple sclerosis
, 2010 Oligodendrocytes are the principal target of immune attack in multiple sclerosis (MS), where the immune system attacks the myelin sheath, leading to oligodendrocyte demise, compromised axonal saltatory conduction and eventually neuronal degeneration ...
Sevastou, I.
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