Results 11 to 20 of about 17,381 (266)
Chromatin remodelers in oligodendroglia [PDF]
Glia, 2020 Oligodendrocytes, the myelinating cells in the vertebrate central nervous system, produce myelin sheaths to enable saltatory propagation of action potentials.
C. Parras +3 more
semanticscholar +5 more sources
Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and mutant multiple system atrophy [PDF]
Acta Neuropathologica Communications, 2014 p25α/tubulin polymerization promoting protein (TPPP) is an oligodendroglial protein that plays crucial roles including myelination, and the stabilization of microtubules.
Kiyobumi Ota +10 more
core +4 more sources
Oligodendroglia: metabolic supporters of neurons. [PDF]
Journal of Clinical Investigation, 2017 Oligodendrocytes are glial cells that populate the entire CNS after they have differentiated from oligodendrocyte progenitor cells. From birth onward, oligodendrocytes initiate wrapping of neuronal axons with a multilamellar lipid structure called myelin.
T. Philips, J. Rothstein
semanticscholar +4 more sources
Oligodendroglia metabolically support axons and contribute to neurodegeneration [PDF]
Nature, 2012 Oligodendroglia support axon survival and function through mechanisms independent of myelination, and their dysfunction leads to axon degeneration in several diseases. The cause of this degeneration has not been determined, but lack of energy metabolites
Youngjin Lee +12 more
semanticscholar +6 more sources
Altered oligodendroglia and astroglia in chronic traumatic encephalopathy [PDF]
Acta Neuropathologica, 2020 Chronic traumatic encephalopathy (CTE) is a progressive tauopathy found in contact sport athletes, military veterans, and others exposed to repetitive head impacts (RHI)1–6. White matter atrophy and axonal loss have been reported in CTE but have not been
K. Blake Chancellor +8 more
semanticscholar +8 more sources
Pathology of oligodendroglia: An overview [PDF]
Neuropathology, 2017 Oligodendroglia are cells responsible for creating myelin sheaths for axons in the CNS. However, pathologies of oligodendroglia other than demyelination are not well understood due to the lack of adequate methods of characterizing pathological conditions affecting oligodendroglia in human tissue. This review discusses three major topics with the aim of
T. Komori
semanticscholar +4 more sources
Cell Communication and Signaling, 2022 Background The contribution of native or modified oligodendroglia-derived extracellular vesicles (OL-EVs) in controlling chronic inflammation is poorly understood. In activated microglia, OL-EVs contribute to the removal of cytotoxic proteins following a
Bram Van den Broek +8 more
doaj +2 more sources
Disrupted CXCR2 Signaling in Oligodendroglia Lineage Cells Enhances Myelin Repair in a Viral Model of Multiple Sclerosis. [PDF]
Journal of Virology, 2019 CXCR2 is a chemokine receptor expressed on oligodendroglia that has been implicated in the pathogenesis of neuroinflammatory demyelinating diseases as well as enhancement of the migration, proliferation, and myelin production by oligodendroglia. Using an
Cheng, Yuting +9 more
core +2 more sources
Frontiers in Genetics, 2018 Numerous genetic risk loci are found to associate with major neuropsychiatric disorders represented by schizophrenia. The pathogenic roles of genetic risk loci in psychiatric diseases are further complicated by the association with cell lineage- and/or ...
Xianjun Chen +3 more
doaj +2 more sources
Cell Reports, 2023 Summary: Traumatic brain injury (TBI) is a leading cause of chronic brain impairment and results in a robust, but poorly understood, neuroinflammatory response that contributes to the long-term pathology.
Raquel Garza +14 more
doaj +2 more sources