Results 31 to 40 of about 15,205 (212)

Ultrastructural study of the effects of cyclosporine in the brainstem of Wistar rats submitted to the ethidium bromide demyelinating model Estudo ultra-estrutural dos efeitos da ciclosporina no tronco encefálico de ratos Wistar submetidos ao modelo desmielinizante do brometo de etídio

Arquivos de Neuro-Psiquiatria, 2008
The ethidium bromide-demyelinating model (EB) was used to study remyelination in the brainstem under the use of cyclosporine (CsA). Wistar rats were submitted to intracisternal injection of 0.1% EB or 0.9% saline solution, and others were taken as ...
Eduardo Fernandes Bondan, Maria Anete Lallo, Dominguita Lühers Graça   +2 more
doaj   +1 more source

Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. [PDF]

, 2013
NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as oligodendroglial progenitor cells, but the fate and function of these cells remain ...
Chung, S-H, Deng, W, Guo, F, Jiang, P, Pleasure, DE   +4 more
core   +2 more sources

The expanding toolkit of translating ribosome affinity purification [PDF]

, 2017
Translating ribosome affinity purification is a method initially developed for profiling mRNA from genetically defined cell types in complex tissues. It has been applied both to identify target molecules in cell types that are important for controlling a
Dougherty, Joseph D
core   +2 more sources

Genetic and Epigenetic Alterations Underlie Oligodendroglia Susceptibility and White Matter Etiology in Psychiatric Disorders

Frontiers in Genetics, 2018
Numerous genetic risk loci are found to associate with major neuropsychiatric disorders represented by schizophrenia. The pathogenic roles of genetic risk loci in psychiatric diseases are further complicated by the association with cell lineage- and/or ...
Xianjun Chen, Huifeng Duan, Lan Xiao, Jingli Gan   +3 more
doaj   +1 more source

The AMPK activator metformin improves recovery from demyelination by shifting oligodendrocyte bioenergetics and accelerating OPC differentiation

Frontiers in Cellular Neuroscience, 2023
Multiple Sclerosis (MS) is a chronic disease characterized by immune-mediated destruction of myelinating oligodendroglia in the central nervous system. Loss of myelin leads to neurological dysfunction and, if myelin repair fails, neurodegeneration of the
Mohanlall Narine, Mohanlall Narine, Maryam A. Azmi, Martin Umali, Ashley Volz, Holly Colognato   +5 more
doaj   +1 more source

Phenotype overlap in glial cell populations: astroglia, oligodendroglia and NG-2(+) cells. [PDF]

, 2015
The extent to which NG-2(+) cells form a distinct population separate from astrocytes is central to understanding whether this important cell class is wholly an oligodendrocyte precursor cell (OPC) or has additional functions akin to those classically ...
Alix, Alix, Arranz, Badrah Alghamdi, Barres, Bergles, Bergles, Butt, Carmen, Carroll, Casper, Chiu, Choi, Choi, Choi, Chung, Clarke, Diers-Fenger, Dimou, Dyer, Dyer, Federoff, Franklin, Godfraind, Grass, Greenwood, Guo, Hamilton, He, Hirsch, Honsa, Kang, Karram, Komitova, Komitova, Kukley, Leoni, Levine, Levine, Levison, Liu, Lord, Lytle, Malatesta, Matthias, Merchan, Michalski, Nair, Nishiyama, Nishiyama, Ong, Peters, Polito, Raff, Redwine, Reyners, Richardson, Rivers, Robert Fern, Skoff, Skoff, Small, Spassky, Vaughn, Vaughn, Vaughn, Wigley, Wilson, Windrem, Wolff, Wu, Yuan, Zerlin, Zhu, Zhu, Ziskin   +75 more
core   +3 more sources

Sleep Disturbance in Bipolar Disorder: Neuroglia and Circadian Rhythms

Frontiers in Psychiatry, 2019
The worldwide prevalence of sleep disorders is approximately 50%, with an even higher occurrence in a psychiatric population. Bipolar disorder (BD) is a severe mental illness characterized by shifts in mood and activity.
Luca Steardo, Renato de Filippis, Elvira Anna Carbone, Cristina Segura-Garcia, Alexei Verkhratsky, Alexei Verkhratsky, Pasquale De Fazio   +6 more
doaj   +1 more source

SIRT2, tubulin deacetylation, and oligodendroglia differentiation [PDF]

Cell Motility, 2007
AbstractThe mammalian silent information regulator 2 (SIRT2) is an NAD‐dependent histone deacetylase with known roles in the regulation of the cell cycle. SIRT2 is also a tubulin deacetylase functioning as an early mitotic checkpoint, but its roles in regulating cytoplasmic microtubule dynamics were unknown.
Bor Luen, Tang, Christelle En Lin, Chua
openaire   +2 more sources

Quetiapine Modulates Histone Methylation Status in Oligodendroglia and Rescues Adolescent Behavioral Alterations of Socially Isolated Mice

Frontiers in Psychiatry, 2020
Epigenetic alterations and impaired oligodendroglial myelination in the prefrontal cortex have been shown to correlate with behavioral and cognitive dysfunctions in social deprivation.
Xianjun Chen, Xianjun Chen, Hao Liu, Jingli Gan, Xiaorui Wang, Guangdan Yu, Tao Li, Xuejun Liang, Bin Yu, Lan Xiao, Lan Xiao   +10 more
doaj   +1 more source

FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy [PDF]

, 2013
Multiple system atrophy is a parkinsonian neurodegenerative disorder. It is cytopathologically characterized by accumulation of the protein p25α in cell bodies of oligodendrocytes followed by accumulation of aggregated α-synuclein in so-called glial ...
Fillon, Gwenaëlle, Gai, Wei-Ping, Gysbers, Amanda, Haass, Christian, Halliday, Glenda,, Hansen, Hanne, Jensen, Poul, Kahle, Philipp, Kragh, Christine, Lubetzki, Catherine, Neumann, Manuela, Richter-Landsberg, Christian, Smith, Wanli, Zalc, Bernard   +13 more
core   +3 more sources