Results 21 to 30 of about 11,172 (159)

DNA Hypermethylation Induced by L-Methionine Leads to Oligodendroglial and Myelin Deficits and Schizophrenia-Like Behaviors in Adolescent Mice

Frontiers in Neuroscience, 2021
Increasing evidence has demonstrated that in addition to dysfunction of neuronal circuitry, oligodendroglial dysfunction and/or disruption of white matter integrity are found in the brains of patients with schizophrenia.
Xianjun Chen, Xianjun Chen, Nan-Xin Huang, Yong-Jie Cheng, Qi-Yan Cai, Yan-Ping Tian, Xing-Shu Chen, Xing-Shu Chen, Lan Xiao   +8 more
doaj   +1 more source

Live-cell metabolic analysis of oligodendroglia isolated from postnatal mouse brain and spinal cord

STAR Protocols, 2022
Summary: This protocol describes isolation and live-cell metabolic analysis of O4+ oligodendroglia from brain and spinal cord of postnatal mice. We have optimized existing protocols for O4+ isolation from neonatal brain and expanded the protocol to ...
Luipa Khandker, Teresa L. Wood
doaj   +1 more source

Glial and Vascular Cell Regulation of the Blood-Brain Barrier in Diabetes [PDF]

Diabetes & Metabolism Journal, 2022
As a structural barrier, the blood-brain barrier (BBB) is located at the interface between the brain parenchyma and blood, and modulates communication between the brain and blood microenvironment to maintain homeostasis.
Xiaolong Li, Yan Cai, Zuo Zhang, Jiyin Zhou   +3 more
doaj   +1 more source

Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits

Nature Communications, 2020
Myelination optimizes conduction speed of excitatory neurons. However, whether myelination of interneurons (INs) refines cortical networks is unclear.
Najate Benamer, Marie Vidal, Maddalena Balia, María Cecilia Angulo   +3 more
doaj   +1 more source

Autophagy in α-Synucleinopathies—An Overstrained System

Cells, 2021
Alpha-synucleinopathies comprise progressive neurodegenerative diseases, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA).
Lisa Fellner, Elisa Gabassi, Johannes Haybaeck, Frank Edenhofer   +3 more
doaj   +1 more source

Gliogenic Potential of Single Pallial Radial Glial Cells in Lower Cortical Layers

Cells, 2021
During embryonic development, progenitor cells are progressively restricted in their potential to generate different neural cells. A specific progenitor cell type, the radial glial cells, divides symmetrically and then asymmetrically to produce neurons ...
Ana Cristina Ojalvo-Sanz, Laura López-Mascaraque   +1 more
doaj   +1 more source

Glioneuronal apoptosis and neuroinflammation in drug resistant temporal lobe epilepsy

Неврология, нейропсихиатрия, психосоматика, 2023
The study of glioneuronal apoptosis and neuroinflammation is extremely important for understanding the causes of epilepsy. Currently, the focus is on neuronal apoptosis and certain aspects of neuroinflammation, while glial apoptosis remains poorly ...
T. V. Sokolova, A. V. Litovchenko, N. M. Paramonova, V. R. Kasumov, S. V. Kravtsova, V. G. Nezdorovina, D. A. Sitovskaya, E. N. Skiteva, E. D. Bazhanova, Y. M. Zabrodskaya   +9 more
doaj   +1 more source

Mending the blood-brain barrier with photobiomodulation: insights from a humanized tricellular transwell model. [PDF]

J Physiol
The Journal of Physiology, Volume 604, Issue 14, Page 5690-5691, 15 July 2026.
Verkhratsky A.
europepmc   +2 more sources

Oligodendroglia vulnerability in the human dorsal striatum in Parkinson's disease. [PDF]

Acta Neuropathol
Oligodendroglia are the responsible cells for myelination in the central nervous system and their involvement in Parkinson's disease (PD) is poorly understood.
Barba-Reyes JM, Harder L, Marco Salas S, Jaisa-Aad M, Muñoz-Castro C, Garma LD, Rafati N, Nilsson M, Hyman BT, Serrano-Pozo A, Muñoz-Manchado AB.   +10 more
europepmc   +2 more sources

Ultrastructural study of the effects of cyclosporine in the brainstem of Wistar rats submitted to the ethidium bromide demyelinating model Estudo ultra-estrutural dos efeitos da ciclosporina no tronco encefálico de ratos Wistar submetidos ao modelo desmielinizante do brometo de etídio

Arquivos de Neuro-Psiquiatria, 2008
The ethidium bromide-demyelinating model (EB) was used to study remyelination in the brainstem under the use of cyclosporine (CsA). Wistar rats were submitted to intracisternal injection of 0.1% EB or 0.9% saline solution, and others were taken as ...
Eduardo Fernandes Bondan, Maria Anete Lallo, Dominguita Lühers Graça   +2 more
doaj   +1 more source