Results 221 to 230 of about 188,463 (312)

Use of high-affinity scFv antibody NUsc1 for isolation and sensitive detection of Alzheimer's-associated amyloid beta oligomers. [PDF]

J Biol Chem
Campos RM, Carraro MF, Bitencourt ALB, Jerisha JJ, Ayon NJ, Juska VB, Pinheiro NR, Johnson EA, Nowar RN, McGee JP, Alfaro ME, Oberholzer MV, Grippo V, Cline EN, Viola KL, Kelleher NL, Habif M, Jerusalinsky DA, Shekhawat GS, Elmor MB, Lah JJ, Levey AI, Klein WL, Sebollela A.   +23 more
europepmc   +1 more source

Continuous and Large‐Scale: ELEANOR, the Soft Architected Arm Inspired by the Elephant Trunk

Advanced Intelligent Systems, EarlyView.
A large‐scale, architected continuum robot inspired by the macroscopic properties of the African elephant trunk achieves adaptive elephant‐like movements and whole‐body grasping. The results demonstrate that designing from the natural system’s macroscopic properties, rather than prescribing behaviors, provides a powerful strategy for developing ...
Giovanna A. Naselli, Anderson B. Nardin, Seonggun Joe, Ryan Drinkwater, Enrico Donato, Diego Bianchi, Egidio Falotico, Michel C. Milinkovitch, Lucia Beccai   +8 more
wiley   +1 more source

Localized amyloid-β oligomers in the lateral entorhinal cortex drives olfactory dysfunction through aberrant neuronal and network activity. [PDF]

Acta Neuropathol Commun
Pan T, Fang J, Wang X, Chen Y, Li S, Qiu G, Sun C, Liu C, Li A, Chen F.   +9 more
europepmc   +1 more source

Functional Polymer‐Engineered Magnetic Nanoparticles as Dual‐Modal Theragnostic Probes for Early Alzheimer's Disease Detection and Therapy

Advanced NanoBiomed Research, EarlyView.
The nanoparticle consists of a 3 nm iron oxide core functionalized with an amphiphilic polymer coating containing Aβ‐targeting DSA moieties and biocompatible PEG chains. This design supports measurable transport in a BBB‐related model and specific interaction with Aβ species, while providing MRI contrast enhancement for diagnosis and therapeutic ...
Ao Shen, Liwen Zhang, Helen Forgham, Jiayuan Zhu, Xumin Huang, Changkui Fu, Ibrahim Javed, Thomas P. Davis, Ruirui Qiao   +8 more
wiley   +1 more source

Direct synthesis of molecularly imprinted nanozymes with a biomimetic catalytic motif for glycosidic bond cleavage. [PDF]

Front Chem
Lakavathu M, Zhao Y.
europepmc   +1 more source

Enhancing Reaction Kinetics and Structural Control in N‐Carboxyanhydride (NCA) Polypeptide Synthesis by Structurally Tuned Azamacrocyclic Ligands

Angewandte Chemie, EarlyView.
Azamacrocycles provide a tunable platform for rapid N‐carboxyanhydride (NCA) Ring‐Opening Polymerization (ROP). Changing the methylation pattern switches the macrocycle from an external catalyst (N14Me3) to a covalent initiator‐catalyst (IniCat, N14Me1), delivering controlled polypeptide growth under open‐vessel conditions.
Paulina Maksym, Adam Gorczynski, Robert D. Murphy, Gianluca Bartolini Torres, Roksana Wygoda, Karol Garbaczewski, Giuseppe Forte, Giuseppe Consiglio, Yixuan Chen, Sébastien Perrier, Andreas Heise   +10 more
wiley   +1 more source

0N4R Tau aggregates producing morphologically different and structurally similar "on-path" and "off-path" oligomers.

Chem Commun (Camb)
Skrehot JT, Matveyenka M, Kurouski D.
europepmc   +1 more source

Biomolecular assemblies through weak noncovalent interactions: Higher-order transient structures and their condensate phase. [PDF]

Proc Natl Acad Sci U S A
MacKinnon R, Haselwandter CA.
europepmc   +1 more source

Mechanistic Control of Cathode–Electrolyte Interphase Formation in Gel Polymer Electrolyte for Lithium‐Ion Batteries

Angewandte Chemie, EarlyView.
To regulate a distinct degradation pathway introduced by residual monomers in in‐situ gel polymer electrolytes (GPEs), tris(4‐fluorophenyl)phosphine (TFPP) is coupled with a voltage hold (VH) protocol. TFPP first covers the high‐Ni cathode surface and then preferentially decomposes during the hold step, forming a cathode–electrolyte interphase (CEI ...
Sang Goo Kang, Jeonghyun Ko, Gunyoung Kim, Jaehoon Choi, Jong Hyeok Park   +4 more
wiley   +1 more source