Results 231 to 240 of about 188,463 (312)

Nanoscale morphological and structural analysis of round and donut oligomers formed by C-terminal domain of TDP-43.

Phys Chem Chem Phys
Pickett D, Purvinsh Y, Skrehot JT, Warren D, Kurouski D.   +4 more
europepmc   +1 more source

Non‐Buckling Stacks of Nanocarbon Molecules

Angewandte Chemie, EarlyView.
A nanometer‐sized nanocarbon molecule with a central octagon was synthesized by optimizing a tetrameric macrocyclization via concentration‐dependent yield analysis (CYAN). The slightly contorted molecular structure was found to be frozen in a dimeric stack in solution, whereas dissociation into monomers liberated the molecule to undergo buckling ...
Koki Ikemoto, Reijiro Yamamoto, Renki Sakai, Yuzuka Shoji, Shunji Takemura, Elisa Nobre, Toshiya M. Fukunaga, Xinyi Xiao, Hiroyuki Isobe   +8 more
wiley   +1 more source

The Paradox of Tau and RNA-Binding Proteins: How Adaptive Stress Granule Regulation Becomes Pathological with Aging. [PDF]

Cells
Wolozin B, Best M, Ellini M, Ma Y, Bok S, Hwang D, Filipponi C.   +6 more
europepmc   +1 more source

Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids

Angewandte Chemie, EarlyView.
Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar, Manas Joshi, Abhishek Chatterjee   +2 more
wiley   +1 more source

Switching ATP‐Forming Phosphoryl‐Transfer Chemistry With a Restricted Set of Amino Acids

Angewandte Chemie, EarlyView.
Constraints on amino acid composition relevant to prebiotic chemistry reshape enzyme chemistry by replacing the canonical mechanism within a conserved protein fold with a distinct ATP‐forming reaction, ADP disproportionation. Such constraints generate alternative catalytic solutions not observed in modern enzymes and point to chemically plausible early
Sota Yagi, Subrata Dasgupta, Shunsuke Tagami, Satoshi Akanuma   +3 more
wiley   +1 more source

Defined Nylon Oligomers Enable Mechanistic Insight Into Enzymatic Polyamide Depolymerization. [PDF]

ChemSusChem
Dewi S, Puetz H, Schwaneberg U, Hartmann L.   +3 more
europepmc   +1 more source

The Dual Nature of Sesamol: Tyrosinase-Dependent Bioactivation from an Inhibitor to a Cytotoxic Pro-Oxidant. [PDF]

Int J Mol Sci
Tanaka H, Nishimaki-Mogami T, Ito S, Wakamatsu K.   +3 more
europepmc   +1 more source

Continuous and Divergent Biotransformation of β-Ketoesters Into Enantiomerically Pure β-Hydroxyacids or Their Oligomers Through a Telescoped Multienzyme Cascade. [PDF]

Chembiochem
Pota G, Andrés-Sanz D, Maiz-Iginitz A, Armendáriz-Ruiz MA, Sardon H, Vitiello G, Califano V, Costantini A, López-Gallego F.   +8 more
europepmc   +1 more source