Non‐Anticoagulant Heparin: An In Vitro Investigation of a Novel Therapeutic Approach for Oral Cancer
ABSTRACT Background Oral squamous cell carcinoma (OSCC) represents a significant global oral health concern. Non‐anticoagulant heparin (NH) emerges as a promising solution considering the enhanced survival observed with anticoagulants in cancer treatment. Methods We used the MTS assay (0/24/48/72 h), scratch assay (MuviCyte, 0–18 h), invasion Matrigel (
S. A. Hamza+6 more
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Growth and gastrointestinal tolerance of healthy formula-fed infants: a multicentre, prospective observational study. [PDF]
Blesa-Baviera L+8 more
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Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin+6 more
wiley +1 more source
Bioactive Ingredients, Functions, and Development Strategies of <i>Phascolosoma esculenta</i>-An Edible Marine Organism: A Review. [PDF]
Chen L, Xu W, Zhu R, Xu S, Chen L, Li H.
europepmc +1 more source
Transplastomic expression of mannanase in lettuce and tobacco chloroplasts and inhibition of Candida albicans from oral cancer patient samples by plant enzyme cocktail. Summary Candida albicans is a human pathogen responsible for several diseases. C. albicans cell wall contains chitin, glucan and mannan.
Iqra Fatima+2 more
wiley +1 more source
Bioconversion of Mushroom Chitin-Rich Waste into Valuable Chitin Oligosaccharides Using a Combined Approach of Biocatalysis and Precision Fermentation. [PDF]
Windels A+6 more
europepmc +1 more source
Engineering Gypsophila elegans hairy root cultures to produce endosomal escape‐enhancing saponins
Summary The limited cytosolic delivery of DNA and protein‐based therapeutics due to endosomal entrapment reduces drug efficacy, increasing treatment costs and possible side effects in human and veterinary medicine as a consequence of higher administered dosages.
Elia Lacchini+4 more
wiley +1 more source
New insights in amino sugar metabolism by the gut microbiome. [PDF]
Shen W, de Boer JF, Kuipers F, Fu J.
europepmc +1 more source
Posttranslational modifications of heterologous proteins expressed in Nicotiana benthamiana
Summary The success of Nicotiana benthamiana as a workhorse for heterologous protein production is closely linked to its accessibility and tolerance to genetic manipulation, allowing efficient engineering of posttranslational protein modifications (PTMs) that are critical for the function and stability of heterologous proteins.
Kathrin Göritzer+2 more
wiley +1 more source
Impact of Selected Natural Bioactive Substances on Immune Response and Tight Junction Proteins in Broiler Chickens. [PDF]
Csernus B+8 more
europepmc +1 more source