Results 31 to 40 of about 79,223 (263)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Safety and efficacy of Bacillus subtilis KCCM 10673P and Aspergillus oryzae KCTC 10258BP when used as a technological feed additive for all animal species

open access: yesEFSA Journal, 2018
The additive consists of single strains of Bacillus subtilis and Aspergillus oryzae, to be used in combination as a technological additive (proposed functional group: Substances for the reduction of anti‐nutritional factors) in feed materials for all ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +25 more
doaj   +1 more source

Biosynthesis of food constituents: Saccharides. 1. Monosaccharides, oligosaccharides, and related compounds - a review

open access: yesCzech Journal of Food Sciences, 2005
This review article presents a survey of selected principal biosynthetic pathways that lead to the most important monosaccharides, oligosaccharides, sugar alcohols, and cyclitols in foods and in food raw materials and informs nonspecialist readers about ...
Jan Velíšek, Karel Cejpek
doaj   +1 more source

Chondroitin Sulfate and Its Derivatives: A Review of Microbial and Other Production Methods

open access: yesFermentation, 2022
Chondroitin sulfate (CS) is widely used across the world as a nutraceutical and pharmaceutical. Its high demand and potential limitations in current methods of extraction call for an alternative method of production.
Adeola E. Awofiranye   +5 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Strategies toward protecting group-free glycosylation through selective activation of the anomeric center

open access: yesBeilstein Journal of Organic Chemistry, 2017
Glycosylation is an immensely important biological process and one that is highly controlled and very efficient in nature. However, in a chemical laboratory the process is much more challenging and usually requires the extensive use of protecting groups ...
A. Michael Downey, Michal Hocek
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Enzymatically Hydrolysed Common Buckwheat (Fagopyrum esculentum M.) as a Fermentable Source of Oligosaccharides and Sugars

open access: yesApplied Sciences, 2022
Common buckwheat (Fagopyrum esculentum M.) is highly rich in starches and polysaccharides. Nowadays, the use of common buckwheat in brewing processes and functional product development is gaining popularity as it is gluten-free and therefore suitable for
Paulina Streimikyte   +7 more
doaj   +1 more source

Synthesis of Heparin Oligosaccharides. [PDF]

open access: yesChemInform, 2003
An efficient preparation of rare 2-O-benzoyl-3-O-benzyl-1,6-anhydro-beta-l-idopyranose from commercially available diacetone alpha-d-glucose in five straightforward steps is described here. With this key building block in hand, the total syntheses of heparin oligosaccharides with three, five, seven, and nine sugar units are successfully carried out.
Jinq-Chyi, Lee   +4 more
openaire   +2 more sources

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