Results 41 to 50 of about 7,218,425 (297)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Changes in plasma fatty acid composition in females with lipedema following low-carbohydrate vs low-fat diets and associations with pain reduction

Nutrition Journal
Background Lipedema is a chronic female disease characterized by a painful accumulation of adipose tissue in the limbs. Plasma fatty acid (FA) composition has been proposed as a potential modulator of pain.
Julianne Lundanes, Vilde Fiske Nes, Patrik Hansson, Rikard Fristedt, Rikard Landberg, Catia Martins, Siren Nymo   +6 more
doaj   +1 more source

Using 3–6 differences in essential fatty acids rather than 3/6 ratios gives useful food balance scores

Nutrition & Metabolism, 2012
Background The vitamin-like omega-3 and omega-6 essential fatty acids are converted in the body to a large family of hormones which act at selective receptors that occur on nearly every cell and tissue.
Lands Bill, Lamoreaux Etienne
doaj   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam, Anthony Siming Chen, Guido Herrmann   +2 more
wiley   +1 more source

Relación de Ácidos grasos Omega 6 /Omega 3

Revista Digital de Postgrado, 2014
La relación de ácidos grasos (AG)ω6/ω3 de ladieta contemporánea favorece a los AG ω6. El objetivodel estudio fue evaluar el efecto de dietas concantidades crecientes de aceite de pescado (AcP),rico en AG ω3, sobre el crecimiento y las ...
Zury Dominguez
doaj  

Adaptive Observer for Coupled Wave PDE and Infinite ODE With Sampled Data and Unknown Input: Application to Brain Hemodynamics Estimation

International Journal of Adaptive Control and Signal Processing, EarlyView.
This article proposes a convergent adaptive observer for a damped wave PDE and an infinite‐dimensional ODE coupled in cascade using sampled‐in‐space ODE state measurements. The proposed observer estimates the distributed states of the PDE and ODE along with unknown PDE parameters and spatial input.
Zehor Belkhatir, Sarah Mechhoud, Taous‐Meriem Laleg‐Kirati   +2 more
wiley   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde   +5 more
wiley   +1 more source

PECES DULCEACUÍCOLAS COMO ALIMENTO FUNCIONAL: PERFIL DE ÁCIDOS GRASOS EN TILAPIA Y BOCACHICO CRIADOS EN POLICULTIVO PEIXES DE ÁGUA DOCE COMO UM ALIMENTO FUNCIONAL: PERFIL DE ÁCIDOS GRAXOS DE TILÁPIA E BOCACHICO EM POLICULTURA FRESHWATER FISH AS A FUNCTIONAL FOOD: FATTY ACID PROFILE IN POLYCULTURE OF TILAPIA AND BOCACHICO

Biotecnología en el Sector Agropecuario y Agroindustrial, 2012
Para evaluar el efecto de dos estrategias alimentarias y presencia de sustrato para perifiton sobre el perfil de ácidos grasos, características sensoriales y microbiológicas en filetes de tilapia y bocachico, se realizó un policultivo bajo un diseño ...
TATIANA ISABEL RESTREPO V., GONZALO JAIR DÍAZ G., SANDRA CLEMENCIA PARDO C.   +2 more
doaj  

The relationship of dietary omega-3 fatty acid and omega-6 to omega-3 ratio intake and likelihood of type 2 diabetes in a cross-sectional study

BMC Endocrine Disorders
Background There is a belief that consuming a significant amount of omega-3 and omega-6 fatty acids can positively affect chronic diseases. However, the connection between these fatty acids and type 2 diabetes mellitus (T2DM) risk remains unclear.
Ebrahim Shakiba, Yahya Pasdar, Farzaneh Asoudeh, Farid Najafi, Amir Saber, Mohammad Hossein Shakiba, Amir Bagheri   +6 more
doaj   +1 more source