Results 31 to 40 of about 88,129,427 (207)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
, 2023 reservedGli acidi grassi omega-3 (PUFAs n-3) ricoprono un ruolo fondamentale in numerose funzioni metaboliche e di segnale. La necessità di assumerli con la dieta, da una parte stimola la ricerca di nuove formulazioni che possano soddisfare i fabbisogni
VARIO, MATTEO
core
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
IDENTIFICATION OF PHYTOPLANKTON TYPES IN TAMBAK BANDENG WITH HIGH QUALITY OF OMEGA-3
JFMR-Journal of Fisheries and Marine Research, 2019 Microalgae as a source of nutrients, can be a good alternative to the use of high-level organisms. The abundant omega 3 content in plankton, especially phytoplankton, needs to be conducted research on the identification of the types of phytoplankton in ...
Endang Yuli Herawati
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Using omega 3 as an anti-aging treatment
Medisur, 2020 Aging in general, and skin aging in particular, is a deleterious and universal process. Skin aging can be divided into chronological aging and photoaging, the latter being activated through damage to human skin, attributable to repeated exposure to ...
Carlos Iván Zavala Naranjo
doaj
The place of omega-3 and omega-6 acids in supplementary treatment of inflammatory joint diseases
Rheumatology, 2020 Eating habits have been analysed for years as a factor influencing the development of autoimmune diseases and susceptibility to infections. On the basis of research, observational studies and meta-analyses, special attention was paid to omega-3 and omega-
Brygida Kwiatkowska, Maria Maślińska
doaj +1 more source
Alternative Origins for Omega-3 Fatty Acids in the Diet
, 2016 This volume argues for the importance of essential nutrients in our diet. Over the last two decades there has been an explosion of research on the relationship of Omega-3 fatty acids and the importance of antioxidants to human health.http://librarysearch.
Bishop, Karen, Lenihan-Geels, G
core +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Frontiers in Nutrition, 2022 BackgroundThe Dietary Guidelines for Americans (DGA) recommends consuming ~225 g/wk of a variety of seafood providing >1.75 g/wk of long-chain omega-3 fatty acids to reduce cardiovascular disease risk, however individual responses to treatment vary ...
Christine E. Richardson +8 more
doaj +1 more source