Results 21 to 30 of about 24,384 (185)

Impact of fresh grape juice on the pharmacokinetics of omeprazole: results of a food–drug interaction study

Frontiers in Pharmacology
Grapes have been widely used for dietary ailments due to their attributed pharmacological activities. Resveratrol, the chief constituent of grapes, is responsible for their pharmacological benefits.
Tayyaba Iftikhar, Zafar Iqbal, Yasar Shah, Nauman Rahim Khan, Muhammad Abbas, Omer Shehzad, Fazal Hadi, Haseeba Sardar, Ali Abusharha, Maria Daglia, Maria Daglia, Haroon Khan, Haroon Khan   +12 more
doaj   +1 more source

Early effect of oral administration of omeprazole with mosapride as compared with those of omeprazole alone on the intragastric pH

BMC Gastroenterology, 2012
Background The ideal medication for acid-related diseases should have a rapid onset of action to promote hemostasis and cause efficient resolution of symptoms.
Iida Hiroshi, Inamori Masahiko, Fujii Tetsuro, Sekino Yusuke, Endo Hiroki, Hosono Kunihiro, Nonaka Takashi, Koide Tomoko, Takahashi Hirokazu, Yoneda Masato, Goto Ayumu, Abe Yasunobu, Kobayashi Noritoshi, Kirikoshi Hiroyuki, Kubota Kensuke, Saito Satoru, Gotoh Eiji, Maeda Shin, Nakajima Atsushi   +18 more
doaj   +1 more source

Binding of omeprazole to protein targets identified by monoclonal antibodies.

PLoS ONE, 2020
Omeprazole is the most commonly used proton pump inhibitor (PPI), a class of medications whose therapeutic mechanism of action involves formation of a disulfide linkage to cysteine residues in the H+/K+ ATPase pump on gastric secretory cells.
Naw May Pearl Cartee, Michael M Wang
doaj   +2 more sources

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Omeprazole and Risk of Hypertension: Analysis of Existing Literature and the WHO Global Pharmacovigilance Database

Drugs - Real World Outcomes
Introduction The association between omeprazole and hypertension is poorly documented. The summary of product characteristics of omeprazole approved by major regulators did not mention hypertension as an adverse drug event.
Merhawi Bahta, Natnael Russom, Amon Solomon Ghebrenegus, Yohana Tecleab Okubamichael, Mulugeta Russom   +4 more
doaj   +1 more source

Mechanistic Insights Into Photocatalytic Materials for Toxic Pollutants: Environmental Remediation of Personal Care Products

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen, Gunjan Chauhan, Surbhi Soni, Monika Vats, Anand Kumar, Indra Bahadur   +5 more
wiley   +1 more source

Drug poisonings following bariatric surgery: Case series report

British Journal of Clinical Pharmacology, EarlyView.
Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari, Fannie LaJeunesse‐Trempe, Stephen Morley, Caroline Copeland   +3 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Induction of Erythrocyte Shrinkage by Omeprazole

Dose-Response, 2020
Omeprazole, a proton pump inhibitor blocks the H + /K + -ATPase channels of gastric parietal cells. It is used for the treatment of peptic ulcer. Prolonged use of omeprazole may involve in inducing anemia.
Ayesha Naveed, Kashif Jilani, Abu Bakar Siddique, Muhammad Akbar, Muhammad Riaz, Zahid Mushtaq, Muhammad Sikandar, Sajida Ilyas, Ismat Bibi, Asma Asghar, Ghulam Rasool, Muhammad Irfan   +11 more
doaj   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source