Results 71 to 80 of about 109,057 (295)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
An Integrated Multi-Disciplinary Perspectivefor Addressing Challenges of the Human Gut Microbiome
Metabolites, 2020 Our understanding of the human gut microbiome has grown exponentially. Advances in genome sequencing technologies and metagenomics analysis have enabled researchers to study microbial communities and their potential function within the context of a range
Rohan M. Shah +6 more
doaj +1 more source
Computational and Structural Biotechnology Journal, 2021 While cost-effective high-throughput technologies provide an increasing amount of data, the analyses of single layers of data seldom provide causal relations.
Otília Menyhárt, Balázs Győrffy
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Tricks to translating TB transcriptomics. [PDF]
, 2015 Transcriptomics and other high-throughput methods are increasingly applied to questions relating to tuberculosis (TB) pathogenesis. Whole blood transcriptomics has repeatedly been applied to define correlates of TB risk and has produced new insight into ...
Coussens, AK, Deffur, A, Wilkinson, RJ
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
ArrayTrack: a free FDA bioinformatics tool to support emerging biomedical research -- an update
Human Genomics, 2010 ArrayTrack™is a Food and Drug Administration (FDA) bioinformatics tool that has been widely adopted by the research community for genomics studies. It provides an integrated environment for microarray data management, analysis and interpretation. Most of
Xu Joshua +3 more
doaj +1 more source
Plant Communications, 2020 The mechanisms underlying rootzone-localized responses to salinity during early stages of barley development remain elusive. In this study, we performed the analyses of multi-root-omes (transcriptomes, metabolomes, and lipidomes) of a domesticated barley
William Wing Ho Ho +7 more
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Omics-enhanced nanomedicine: integrating multi-omics for precision cancer diagnosis and therapy
Discover OncologyCancer nanomedicine has emerged as a transformative approach in oncology, providing targeted therapeutic strategies with enhanced efficacy and reduced systemic toxicity.
Lihui Yan +5 more
doaj +1 more source