Results 41 to 50 of about 71,004,447 (289)
On the Generalization Ability of On-Line Learning Algorithms [PDF]
IEEE Transactions on Information Theory, 2002 In this paper, it is shown how to extract a hypothesis with small risk from the ensemble of hypotheses generated by an arbitrary on-line learning algorithm run on an independent and identically distributed (i.i.d.) sample of data. Using a simple large deviation argument, we prove tight data-dependent bounds for the risk of this hypothesis in terms of ...
N. CESA BIANCHI +2 more
openaire +4 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Learner support in a distributed learning environment:the use of WWW-based teachware packages
Information Research: An International Electronic Journal, 1997 Various forms of education and training, based on the classical Computer Based Training (CBT), have become well established within companies and in higher education.
Christian Langenbach, Freimut Bodendorf
doaj
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Information Research: An International Electronic Journal, 1997 The aim of the paper is to compare the role of the facilitator with the role of the librarian. Firstly, a list of the role dimensions of the facilitation is described. Secondly, a case study of a facilitation proces is presented.
Trine Schreiber, Camilla Moring
doaj
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Expanding the notion of global learning: Turkish-Dutch teens’ networked configurations for learning [PDF]
, 2020 Digital technology facilitate interactions between learners and resources at a global level. New learner prototypes are therefore proposed, such as the notion of the global learner.
Ünlüsoy, Asli +5 more
core +2 more sources
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The present educational process as a state of the future social system
Дискурс, 2019 Introduction. The work considers formation possibilities of the present educational process for Russian students to provide the future digital economy with staff.Materials and methods.
I. V. Petrova
doaj +1 more source