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The Interconnected World of Dermatology and Ophthalmology

JEADV Clinical Practice, Volume 4, Issue 2, Page 389-399, June 2025.
Medical science, is an integrated field that shares intricate relationship between various organ systems. Similarly, dermatology is inter‐related with various other specialties including ophthalmology. This article depicts the correlation of ophthalmology and dermatology iterating on the genetic diseases, autoimmune diseases, systemic disorders ...
Gyanesh Rathore, Surajit Gorai, Gitikash Purkayastha, Kinnor Das, Prajwal Pudasaini   +4 more
wiley   +1 more source

The genome of Onchocerca volvulus, agent of river blindness [PDF]

Nature Microbiology, 2016
AbstractHuman onchocerciasis is a serious neglected tropical disease caused by the filarial nematode Onchocerca volvulus that can lead to blindness and chronic disability. Control of the disease relies largely on mass administration of a single drug, and the development of new drugs and vaccines depends on a better knowledge of parasite biology.
José M. C. Ribeiro, Julie C. Dunning Hotopp, Robin N. Beech, Denis Voronin, Matthew Dunn, Sasisekhar Bennuru, Prudence Mutowo, James Cotton, Taisei Kikuchi, Taisei Kikuchi, Eleanor J Stanley, Eleanor J Stanley, Sara Lustigman, Thomas R. Unnasch, Isheng J. Tsai, Isheng J. Tsai, Thomas B. Nutman, Nirvana Nursimulu, Matthew Berriman, Stephen R. Doyle, Olivia Lambert, Amruta S. Mhashilkar, Alan Tracey, Nancy Holroyd, Elodie Ghedin, Alexandra Grote, John Parkinson, Lakshmipuram S. Swapna, Matthew B. Rogers, Bhavana Harsha   +29 more
openaire   +3 more sources

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference

Alzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract Recent years have seen major advances in tau‐associated brain disorders through interdisciplinary research spanning molecular biology, neuroimaging, clinical trials, and therapeutic development. The Tau2024 Global Conference, hosted by the Alzheimer's Association, CurePSP, and Rainwater Charitable Foundation, showcased these efforts by ...
Bess Frost, James B. Rowe, Rufus O. Akinyemi, Jose F. Abisambra, Nicholas J. Ashton, Matthias Brendel, Luc Buée, David Butler, Maria C. Carrillo, Peter Chung, Claire D. Clelland, Sarah L. DeVos, Kristophe Diaz, Rebecca M. Edelmayer, Fanny M. Elahi, Ratnavalli Ellajosyula, Colin Ewen, Igor Camargo Fontana, Marie‐Christine Galas, Oskar Hansson, Günter Höglinger, Kanta Horie, Agustín Ibanez, Linde Jacobs, Mahmoud B. Maina, Maura Malpetti, Eric McDade, Will McEwan, Laia Montoliu‐Gaya, Catherine J. Mummery, Miranda E. Orr, Jonathan D. Rohrer, Amy Rommel, Carlos Sastre, Tara L. Spires‐Jones, Boon Lead Tee, Tim J. Viney, Jamie M. Walker, Susanne Wegmann, Kristin Wildsmith, Ravi Yadav, Simin Mahinrad, Claire Sexton   +42 more
wiley   +1 more source

The mitogenome of Onchocerca volvulus from the Brazilian Amazonia focus

Memorias do Instituto Oswaldo Cruz, 2016
We report here the first complete mitochondria genome of Onchocerca volvulus from a focus outside of Africa. An O. volvulus mitogenome from the Brazilian Amazonia focus was obtained using a combination of high-throughput and Sanger sequencing ...
James L Crainey, Túllio RR da Silva, Fernando Encinas, Michel A Marín, Ana Carolina P Vicente, Sérgio LB Luz   +5 more
doaj   +1 more source

Unraveling cross-reactivity of anti-glycan IgG responses in filarial nematode infections

Frontiers in Immunology, 2023
Parasitic nematodes responsible for filarial diseases cause chronic disablement in humans worldwide. Elimination programs have substantially reduced the rate of infection in certain areas, but limitations of current diagnostics for population ...
Laudine M. C. Petralia, Laudine M. C. Petralia, Angela van Diepen, Dieu-Linh Nguyen, Lena A. Lokker, Erliyani Sartono, Sasisekhar Bennuru, Thomas B. Nutman, Kenneth Pfarr, Kenneth Pfarr, Achim Hoerauf, Achim Hoerauf, Samuel Wanji, Jeremy M. Foster, Cornelis H. Hokke   +14 more
doaj   +1 more source

Maternal IgE Influence on Fetal and Infant Health

Immunological Reviews, Volume 331, Issue 1, May 2025.
ABSTRACT Immunoglobulin E (IgE) is the most recently discovered and evolved mammalian antibody type, best known for interacting with mast cells (MCs) as immune effectors. IgE‐mediated antigen sensing by MC provides protection from parasites, venomous animals, bacteria, and other insults to barrier tissues exposed to the environment.
Jozef Balla, Abhay P. S. Rathore, Ashley L. St. John   +2 more
wiley   +1 more source

Nodding syndrome is unlikely to be an autoimmune reaction to leiomodin-1 after infection by Onchocerca volvulus

Biochemistry and Biophysics Reports, 2023
Nodding syndrome is a neurological disease of children in northern Uganda. Infection with the nematode parasite Onchocerca volvulus has been epidemiologically implicated as the cause of the disease.
Kenneth G. Kodja, Sylvester Onzivua, David L. Kitara, Amanda Fong, Patrick Kim, Michael S. Pollanen   +5 more
doaj  

Onchocerciasis transmission in Ghana: persistence under different control strategies and the role of the simuliid vectors. [PDF]

PLoS Neglected Tropical Diseases, 2015
BACKGROUND:The World Health Organization (WHO) aims at eliminating onchocerciasis by 2020 in selected African countries. Current control focuses on community-directed treatment with ivermectin (CDTI).
Poppy H L Lamberton, Robert A Cheke, Peter Winskill, Iñaki Tirados, Martin Walker, Mike Y Osei-Atweneboana, Nana-Kwadwo Biritwum, Anthony Tetteh-Kumah, Daniel A Boakye, Michael D Wilson, Rory J Post, María-Gloria Basañez   +11 more
doaj   +1 more source

Genetic and environmental risk factors for dementia in African adults: A systematic review

Alzheimer's &Dementia, Volume 21, Issue 4, April 2025.
Abstract Dementia, a leading cause of global mortality, disproportionately impacts sub‐Saharan Africans due to complex genetic and environmental interactions. This systematic review evaluated dementia risk factors among sub‐Saharan Africans, identifying significant genetic and environmental influences using the Preferred Reporting Items for Systematic ...
David Mawutor Donkor, Esther Marfo, Ansumana Bockarie, Edward Jenner Tettevi, Maxwell Hubert Antwi, John Dogah, George Nkrumah Osei, David Larbi Simpong   +7 more
wiley   +1 more source

Of mice, cattle, and humans: the immunology and treatment of river blindness.

PLoS Neglected Tropical Diseases, 2008
River blindness is a seriously debilitating disease caused by the filarial parasite Onchocerca volvulus, which infects millions in Africa as well as in South and Central America. Research has been hampered by a lack of good animal models, as the parasite
Judith E Allen, Ohene Adjei, Odile Bain, Achim Hoerauf, Wolfgang H Hoffmann, Benjamin L Makepeace, Hartwig Schulz-Key, Vincent N Tanya, Alexander J Trees, Samuel Wanji, David W Taylor   +10 more
doaj   +1 more source