To eliminate onchocerciasis-associated morbidity, it is important to identify areas where there is still high ongoing Onchocerca volvulus transmission.
Alfred Dusabimana +11 more
doaj +1 more source
Co-infection with Onchocerca volvulus and Loa loa microfilariae in central Cameroon: are these two species interacting? [PDF]
Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L.
Basáñez, M-G +6 more
core +1 more source
The therapeutic efficacy and macrofilaricidal activity of doxycycline for the treatment of river blindness [PDF]
Background. Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival.
Achim Hoerauf +43 more
core +2 more sources
Small RNAs and extracellular vesicles in filarial nematodes: from nematode development to diagnostics [PDF]
Parasitic nematodes have evolved sophisticated mechanisms to communicate with their hosts in order to survive and successfully establish an infection. The transfer of RNA within extracellular vesicles (EVs) has recently been described as a mechanism that
Babayan, S.A. +2 more
core +2 more sources
Stage-specific proteomes from onchocerca ochengi, sister species of the human river blindness parasite, uncover adaptations to a nodular lifestyle [PDF]
Despite 40 years of control efforts, onchocerciasis (river blindness) remains one of the most important neglected tropical diseases, with 17 million people affected.
Adam +155 more
core +6 more sources
Nodding syndrome (NS) and Onchocerca Volvulus (OV) in Northern Uganda
Nodding Syndrome (NS) is a childhood neurological disorder characterized by atonic seizures, cognitive decline, school dropout, muscle weakness, thermal dysfunction, wasting and stunted growth.
David Kitara Lagoro, Denis Anywar Arony
doaj +1 more source
Evidence against Wolbachia symbiosis in Loa loa [PDF]
BACKGROUND: The majority of filarial nematode species are host to Wolbachia bacterial endosymbionts, although a few including Acanthocheilonema viteae, Onchocerca flexuosa and Setaria equina have been shown to be free of infection. Comparisons of species
Akue, Jean-Paul +10 more
core +2 more sources
Após caracterização clínico-epidemiológica da oncocercose na região Yanomâmi, RR, Brasil, iniciada em 1993, a Fundação Nacional de Saúde (FNS) implementou um projeto piloto de controle e tratamento nos pólos de base de Tootobi e Balawaú.
Giovanini E. Coelho +4 more
doaj +1 more source
Observações preliminares sobre a transmissão de oncocercose no rio Toototobi, Amazonas, Brasil [PDF]
Resumo Em dezembro de 1975 os autores estudaram vários fatores que influenciam a transmissão de Onchocerca volvulus ao norte do Amazonas, no rio Toototobi. Observaram que a densidade de microfilarias de O.
A. J. Shelley +2 more
doaj +1 more source
The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness [PDF]
Background: Mass drug administration (MDA) with ivermectin is the cornerstone of efforts to eliminate human onchocerciasis by 2020 or 2025. The feasibility of elimination crucially depends on the effects of multiple ivermectin doses on Onchocerca ...
Basáñez, Maria-Gloria +12 more
core +3 more sources

