Results 41 to 50 of about 26,229 (182)

Onchocerca volvulus: The Road from Basic Biology to a Vaccine.

Trends in Parasitology, 2018
S. Lustigman, Benjamin L. Makepeace, T. Klei, S. Babayan, P. Hotez, D. Abraham, M. Bottazzi   +6 more
semanticscholar   +3 more sources

A four-antigen mixture for rapid assessment of Onchocerca volvulus infection. [PDF]

PLoS Neglected Tropical Diseases, 2009
Onchocerciasis, an infection caused by the filarial nematode Onchocerca volvulus, is a major public health concern. Given the debilitating symptoms associated with onchocerciasis and concerns about recrudescence in areas of previous onchocerciasis ...
Peter D Burbelo, Hannah P Leahy, Michael J Iadarola, Thomas B Nutman   +3 more
doaj   +1 more source

Surveillance for Onchocerciasis-Associated Epilepsy and OV16 IgG4 Testing of Children 6–10 Years Old Should Be Used to Identify Areas Where Onchocerciasis Elimination Programs Need Strengthening

Pathogens, 2022
To eliminate onchocerciasis-associated morbidity, it is important to identify areas where there is still high ongoing Onchocerca volvulus transmission.
Alfred Dusabimana, Joseph Nelson Siewe Fodjo, Michel Mandro Ndahura, Bruno P. Mmbando, Stephen Raimon Jada, Annelies Boven, Eric De Smet, Tony Ukety, Alfred K. Njamnshi, Anne Laudisoit, Steven Abrams, Robert Colebunders   +11 more
doaj   +1 more source

The insufficiency of circulating miRNA and DNA as diagnostic tools or as biomarkers of treatment efficacy for Onchocerca volvulus

Scientific Reports, 2020
Skin snip evaluation for onchocerciasis has insufficient sensitivity when skin microfilarial (mf) densities are low, such as following ivermectin treatment.
C. L. Macfarlane, Shannon Quek, N. Pionnier, J. Turner, S. Wanji, S. Wagstaff, M. Taylor   +6 more
semanticscholar   +1 more source

Preliminary evaluations of 3-dimensional human skin models for their ability to facilitate in vitro the long-term development of the debilitating obligatory human parasite Onchocerca volvulus

PLoS Neglected Tropical Diseases, 2020
Onchocerciasis also known as river blindness is a neglected tropical disease and the world's second-leading infectious cause of blindness in humans; it is caused by Onchocerca volvulus.
Christoph Malkmus, Shabnam Jawahar, Nancy Tricoche, S. Lustigman, J. Hansmann   +4 more
semanticscholar   +1 more source

Onchocerca volvulus

Definitions, 2020
This datasheet on Onchocerca volvulus covers Identity, Distribution, Hosts/Species Affected, Vectors & Intermediate Hosts.
A. Truant, Irma Palazzo, Byung-Kuk Suh, Francis Au   +3 more
semanticscholar   +1 more source

Atividades preliminares do programa de controle e tratamento da oncocercose no território Yanomâmi, Roraima, Brasil

Revista da Sociedade Brasileira de Medicina Tropical, 1997
Após caracterização clínico-epidemiológica da oncocercose na região Yanomâmi, RR, Brasil, iniciada em 1993, a Fundação Nacional de Saúde (FNS) implementou um projeto piloto de controle e tratamento nos pólos de base de Tootobi e Balawaú.
Giovanini E. Coelho, João B.F. Vieira, Cláudio E. Oliveira, Deise A. Francisco, Luís R. Pinheiro   +4 more
doaj   +1 more source

Observações preliminares sobre a transmissão de oncocercose no rio Toototobi, Amazonas, Brasil [PDF]

Acta Amazonica, 1976
Resumo Em dezembro de 1975 os autores estudaram vários fatores que influenciam a transmissão de Onchocerca volvulus ao norte do Amazonas, no rio Toototobi. Observaram que a densidade de microfilarias de O.
A. J. Shelley, J. A. S. Nunes de Mello, R. G. O. Rees   +2 more
doaj   +1 more source

A simple isothermal DNA amplification method to screen black flies for Onchocerca volvulus infection. [PDF]

PLoS ONE, 2014
Onchocerciasis is a debilitating neglected tropical disease caused by infection with the filarial parasite Onchocerca volvulus. Adult worms live in subcutaneous tissues and produce large numbers of microfilariae that migrate to the skin and eyes.
Andy Alhassan, Benjamin L Makepeace, Elwyn James LaCourse, Mike Y Osei-Atweneboana, Clotilde K S Carlow   +4 more
doaj   +1 more source

Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis.

PLoS Neglected Tropical Diseases, 2015
Two major human diseases caused by filariid nematodes are onchocerciasis, or river blindness, and lymphatic filariasis, which can lead to elephantiasis.
Christina A Bulman, Chelsea M Bidlow, Sara Lustigman, Fidelis Cho-Ngwa, David Williams, Alberto A Rascón, Nancy Tricoche, Moses Samje, Aaron Bell, Brian Suzuki, K C Lim, Nonglak Supakorndej, Prasit Supakorndej, Alan R Wolfe, Giselle M Knudsen, Steven Chen, Chris Wilson, Kean-Hooi Ang, Michelle Arkin, Jiri Gut, Chris Franklin, Chris Marcellino, James H McKerrow, Anjan Debnath, Judy A Sakanari   +24 more
doaj   +1 more source