Results 41 to 50 of about 13,344 (260)

A simple isothermal DNA amplification method to screen black flies for Onchocerca volvulus infection. [PDF]

PLoS ONE, 2014
Onchocerciasis is a debilitating neglected tropical disease caused by infection with the filarial parasite Onchocerca volvulus. Adult worms live in subcutaneous tissues and produce large numbers of microfilariae that migrate to the skin and eyes.
Andy Alhassan, Benjamin L Makepeace, Elwyn James LaCourse, Mike Y Osei-Atweneboana, Clotilde K S Carlow   +4 more
doaj   +1 more source

What's in your next-generation sequence data? An exploration of unmapped DNA and RNA sequence reads from the bovine reference individual. [PDF]

, 2015
BackgroundNext-generation sequencing projects commonly commence by aligning reads to a reference genome assembly. While improvements in alignment algorithms and computational hardware have greatly enhanced the efficiency and accuracy of alignments, a ...
Alexander, Leeson J, Decker, Jared E, Kim, JaeWoo, Medrano, Juan F, Schnabel, Robert D, Schroeder, Steven G, Sonstegard, Tad S, Taylor, Jeremy F, Tizioto, Polyana C, Whitacre, Lynsey K   +9 more
core   +1 more source

Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis.

PLoS Neglected Tropical Diseases, 2015
Two major human diseases caused by filariid nematodes are onchocerciasis, or river blindness, and lymphatic filariasis, which can lead to elephantiasis.
Christina A Bulman, Chelsea M Bidlow, Sara Lustigman, Fidelis Cho-Ngwa, David Williams, Alberto A Rascón, Nancy Tricoche, Moses Samje, Aaron Bell, Brian Suzuki, K C Lim, Nonglak Supakorndej, Prasit Supakorndej, Alan R Wolfe, Giselle M Knudsen, Steven Chen, Chris Wilson, Kean-Hooi Ang, Michelle Arkin, Jiri Gut, Chris Franklin, Chris Marcellino, James H McKerrow, Anjan Debnath, Judy A Sakanari   +24 more
doaj   +1 more source

Evidence of suppression of onchocerciasis transmission in the Venezuelan Amazonian focus. [PDF]

, 2016
BACKGROUND: The World Health Organization (WHO) has set goals for onchocerciasis elimination in Latin America by 2015. Most of the six previously endemic countries are attaining this goal by implementing twice a year (and in some foci, quarterly) mass ...
Basanez, MG, Borges, D, Botto, C, Camacho, O, Coronel, P, Cortez, J, Escalona, M, Flores, J, Frontado, H, Graterol, B, Grillet, ME, Guerra, F, Margeli, H, Morales, AL, Noya-Alarcón, O, Rodriguez, MA, Ríos, D, Tovar, Y, Unnasch, TR, Villamizar, NJ, Vivas-Martínez, S   +20 more
core   +2 more sources

Extracellular Onchocerca-derived small RNAs in host nodules and blood

Parasites & Vectors, 2015
Background microRNAs (miRNAs), a class of short, non-coding RNA can be found in a highly stable, cell-free form in mammalian body fluids. Specific miRNAs are secreted by parasitic nematodes in exosomes and have been detected in the serum of murine and ...
Juan F Quintana, Benjamin L Makepeace, Simon A Babayan, Alasdair Ivens, Kenneth M Pfarr, Mark Blaxter, Alexander Debrah, Samuel Wanji, Henrietta F Ngangyung, Germanus S Bah, Vincent N Tanya, David W Taylor, Achim Hoerauf, Amy H Buck   +13 more
doaj   +1 more source

Epilepsy in Onchocerca volvulus Sero-Positive Patients From Northern Uganda—Clinical, EEG and Brain Imaging Features

Frontiers in Neurology, 2021
Globally, epilepsy is the most common chronic neurological disorder. The incidence in sub-Saharan Africa is 2-3 times higher than that in high income countries.
Rodney Ogwang, Rodney Ogwang, Rodney Ogwang, Albert Ningwa, Albert Ningwa, Pamela Akun, Pamela Akun, Paul Bangirana, Ronald Anguzu, Ronald Anguzu, Ronald Anguzu, Rajarshi Mazumder, Noriko Salamon, Oliver Johannes Henning, Charles R. Newton, Charles R. Newton, Catherine Abbo, Amos Deogratius Mwaka, Kevin Marsh, Richard Idro, Richard Idro, Richard Idro   +21 more
doaj   +1 more source

Recombinant expression systems: the obstacle to helminth vaccines? [PDF]

, 2007
A
Claerebout, Edwin, De Maere, Veerle, Geldhof, Peter, Vercruysse, Jozef   +3 more
core   +2 more sources

Factors affecting onchocerciasis transmission: Lessons for infection control [PDF]

, 2017
Introduction: Onchocerca volvulus infects in excess of 15 million people. The vectors are Simulium blackflies, varieties of which differ in their ecologies, behaviour and vectorial abilities.
Cheke, Robert A.
core   +1 more source

Simuliidae and the transmission and control of human Onchocerciasis in Latin America

Cadernos de Saúde Pública, 1991
Factors that affect the propensity of a simuliid species to act as a host to Onchocerca volvulus and to naturally transmit this filarial worm in nature are discussed.
A. J. Shelley
doaj   +1 more source

Elimination of onchocerciasis in Ecuador: findings of post-treatment surveillance. [PDF]

, 2018
BACKGROUND: The Esmeraldas focus of onchocerciasis in Ecuador expanded geographically during the 1980s and was associated with severe ocular and skin disease.
AG Guevara, AJ Shelley, AJ Shelley, AJ Shelley, B Thylefors, CR Katholi, EW Cupp, EW Cupp, HL Carvajal, JC Vieira, M Arzube, M Charalambous, M Charalambous, MA Rodríguez-Pérez, Mario A. Rodriguez-Perez, MG Basanez, Philip J. Cooper, PJ Cooper, PJ Cooper, R Lovato, Raquel Lovato, RC Collins, RC Collins, RH Guderian, RH Guderian, RH Guderian, RH Guderian, RH Guderian, RH Guderian, RH Guderian, RJ Hay, Roberto Proaño, Ronald H. Guderian, S Wetten, Thomas Unnasch, WHO, WS Procunier, WS Procunier, Ángel Guevara   +38 more
core   +1 more source