Results 1 to 10 of about 28,700 (244)

OV16 Seroprevalence among Persons with Epilepsy in Onchocerciasis Endemic Regions: A Multi-Country Study [PDF]

open access: goldPathogens, 2020
There is growing epidemiological evidence that onchocerciasis may induce epilepsy. High prevalence of onchocerciasis has been reported in onchocerciasis-meso and hyper-endemic regions.
Alfred Dusabimana   +5 more
doaj   +2 more sources

Assessment of community’s knowledge, attitude and practice about onchocerciasis and community directed treatment with Ivermectin in Quara District, north western Ethiopia [PDF]

open access: goldParasites & Vectors, 2014
Background The African Program for Onchocerciasis Control (APOC) has been working with ultimate goal of reducing the public health and socio-economic problems associated with onchocerciasis within a period of 12–15 years.
Fitsum Weldegebreal   +3 more
doaj   +2 more sources

Advancing a Human Onchocerciasis Vaccine From Antigen Discovery to Efficacy Studies Against Natural Infection of Cattle With Onchocerca ochengi

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Human onchocerciasis is a devastating neglected tropical disease caused by infection of the filarial nematode Onchocerca volvulus. The infection can cause irreversible visual impairment or blindness and stigmatizing dermatitis.
Bin Zhan   +3 more
doaj   +2 more sources

Epidemiology and Risks Survey of Onchocerca volvulus Infection in Igbo-Eze North Local Government Area, Enugu State, Nigeria [PDF]

open access: yesTropical Medicine and Infectious Disease
Background: An epidemiological survey of Onchocerca volvulus infection and onchocerciasis in Igbo-Eze North Local Government Area, Enugu State, Nigeria, was undertaken to assess its distribution and risks among individuals in the area.
Ifeoma Esther Aniaku   +9 more
doaj   +2 more sources

Onchocerciasis control in Ghana (1974–2016)

open access: yesParasites & Vectors, 2021
Background The control of onchocerciasis in Ghana started in 1974 under the auspices of the Onchocerciasis Control Programme (OCP). Between 1974 and 2002, a combination of approaches including vector control, mobile community ivermectin treatment, and ...
Nana-Kwadwo Biritwum   +5 more
doaj   +2 more sources

Update on the current status of onchocerciasis in Côte d’Ivoire following 40 years of intervention: Progress and challenges [PDF]

open access: gold, 2018
Background Onchocerciasis control in Côte d’Ivoire started with aerial insecticide spraying in 1974 and continued with community directed treatment with ivermectin (CDTi) from 1992 to the present.
Benjamin G. Koudou   +10 more
openalex   +7 more sources

Repurposing of Anti-Infectives for the Management of Onchocerciasis Using Machine Learning and Protein Docking Studies [PDF]

open access: yesBioinformatics and Biology Insights
There is a need to improve the discovery of new drugs for neglected tropical diseases (NTDs), as the lack of financial incentives has slowed their development. Currently, ivermectin and moxidectin are used in the management of onchocerciasis.
Cyril Tetteh   +7 more
doaj   +2 more sources

Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning.

open access: yesPLoS Neglected Tropical Diseases, 2021
Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across
Elizabeth A Cromwell   +224 more
doaj   +2 more sources

Recognising the neurological burden of onchocerciasis: the need to include onchocerciasis-associated epilepsy in onchocerciasis global health metrics [PDF]

open access: yesInfectious Diseases of Poverty
Background Historically, onchocerciasis has been recognised for its dermatological and ophthalmological manifestations, such as blindness. However, growing epidemiological evidence indicates that onchocerciasis is also associated with neurological ...
Luís-Jorge Amaral, Robert Colebunders
doaj   +2 more sources

Stigma and epilepsy in onchocerciasis-endemic regions in Africa: a review and recommendations from the onchocerciasis-associated epilepsy working group

open access: yesInfectious Diseases of Poverty, 2019
Background In onchocerciasis-endemic areas, particularly in those with a sub-optimal onchocerciasis control programme, a high prevalence of epilepsy is observed. Both onchocerciasis and epilepsy are stigmatizing conditions.
Sarah O’Neill   +10 more
doaj   +2 more sources

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