Frontiers in Cellular and Infection Microbiology, 2022 Human onchocerciasis is a devastating neglected tropical disease caused by infection of the filarial nematode Onchocerca volvulus. The infection can cause irreversible visual impairment or blindness and stigmatizing dermatitis.
Bin Zhan +3 more
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Onchocerciasis control in Ghana (1974–2016)
Parasites & Vectors, 2021 Background The control of onchocerciasis in Ghana started in 1974 under the auspices of the Onchocerciasis Control Programme (OCP). Between 1974 and 2002, a combination of approaches including vector control, mobile community ivermectin treatment, and ...
Nana-Kwadwo Biritwum +5 more
doaj +2 more sources
Recognising the neurological burden of onchocerciasis: the need to include onchocerciasis-associated epilepsy in onchocerciasis global health metrics [PDF]
Infectious Diseases of PovertyBackground Historically, onchocerciasis has been recognised for its dermatological and ophthalmological manifestations, such as blindness. However, growing epidemiological evidence indicates that onchocerciasis is also associated with neurological ...
Luís-Jorge Amaral, Robert Colebunders
doaj +2 more sources
How Can Onchocerciasis Elimination in Africa Be Accelerated? Modeling the Impact of Increased Ivermectin Treatment Frequency and Complementary Vector Control [PDF]
Clinical Infectious Diseases, 2018 Background Great strides have been made toward onchocerciasis elimination by mass drug administration (MDA) of ivermectin. Focusing on MDA-eligible areas, we investigated where the elimination goal can be achieved by 2025 by continuation of current ...
S. Verver +12 more
semanticscholar +5 more sources
Onchocerciasis is not a major cause of blindness in two endemic villages in Sierra Leone [PDF]
BMC Research NotesObjective Sierra Leone, a country where onchocerciasis is endemic in 14 of the 16 districts, was the focus of our investigation. Despite 17 rounds of annual ivermectin treatment since 2005, a report circulated by a local politician indicated an increase ...
Ibrahim Kargbo-Labour +10 more
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Infectious Diseases of Poverty, 2019 Background In onchocerciasis-endemic areas, particularly in those with a sub-optimal onchocerciasis control programme, a high prevalence of epilepsy is observed. Both onchocerciasis and epilepsy are stigmatizing conditions.
Sarah O’Neill +10 more
doaj +2 more sources
Prevalence and Sociodemographic Risk Factors of Soil-Transmitted Helminths in Rural Communities Living in Endemic Foci of Onchocerciasis in Southern Gabon [PDF]
PathogensThis prospective survey determined the prevalence and intensity of infections due to geohelminths and the associated risk factors in five onchocerciasis-endemic communities in Gabon between January and February 2020.
Reinne Moutongo Mouandza +10 more
doaj +2 more sources
Infectious Diseases of Poverty, 2019 Background High epilepsy prevalence and incidence have been reported in areas with high onchocerciasis transmission. Recent findings suggest that proper community-directed treatment with ivermectin (CDTI) is potentially able to prevent onchocerciasis ...
Joseph N. F. Siewe +18 more
doaj +2 more sources
Factors associated with Onchocerca volvulus transmission after 20 years of community treatment with ivermectin in savanah and forest areas in Central African Republic: A Cross Sectional Study. [PDF]
PLoS Neglected Tropical DiseasesThe Central African Republic has endemic onchocerciasis in 20 health districts in savannah and forest areas. The country organised a mass distribution campaign of invermectin in 2023 through the National Onchocerciasis Control Programme.
Sylvain Honoré Woromogo +5 more
doaj +2 more sources