Results 11 to 20 of about 28,700 (244)

How Can Onchocerciasis Elimination in Africa Be Accelerated? Modeling the Impact of Increased Ivermectin Treatment Frequency and Complementary Vector Control [PDF]

Clinical Infectious Diseases, 2018
Background Great strides have been made toward onchocerciasis elimination by mass drug administration (MDA) of ivermectin. Focusing on MDA-eligible areas, we investigated where the elimination goal can be achieved by 2025 by continuation of current ...
S. Verver, M. Walker, Young Eun Kim, G. Fobi, A. Tekle, Honorat G M Zoure, S. Wanji, D. Boakye, A. Kuesel, S. D. de Vlas, M. Boussinesq, M. Basáñez, W. Stolk   +12 more
semanticscholar   +7 more sources

Onchocerciasis is not a major cause of blindness in two endemic villages in Sierra Leone [PDF]

BMC Research Notes
Objective Sierra Leone, a country where onchocerciasis is endemic in 14 of the 16 districts, was the focus of our investigation. Despite 17 rounds of annual ivermectin treatment since 2005, a report circulated by a local politician indicated an increase ...
Ibrahim Kargbo-Labour, Victoria Redwood-Sawyerr, Abdulai Conteh, Doris Harding, Mohamed S. Bah, Patricia Houck, Sugandh Juneja, Achille Kabore, Darin Evans, Angela M. Weaver, Yaobi Zhang   +10 more
doaj   +2 more sources

High prevalence of epilepsy in two rural onchocerciasis endemic villages in the Mahenge area, Tanzania, after 20 years of community directed treatment with ivermectin

Infectious Diseases of Poverty, 2018
Background Epilepsy is a neurological disorder with a multitude of underlying causes, which may include infection with Onchocerca volvulus, the parasitic worm that causes human onchocerciasis.
Bruno P. Mmbando, Patrick Suykerbuyk, Mohamed Mnacho, Advocatus Kakorozya, William Matuja, Adam Hendy, Helena Greter, Williams H. Makunde, Robert Colebunders   +8 more
doaj   +2 more sources

Factors associated with Onchocerca volvulus transmission after 20 years of community treatment with ivermectin in savanah and forest areas in Central African Republic: A Cross Sectional Study. [PDF]

PLoS Neglected Tropical Diseases
The Central African Republic has endemic onchocerciasis in 20 health districts in savannah and forest areas. The country organised a mass distribution campaign of invermectin in 2023 through the National Onchocerciasis Control Programme.
Sylvain Honoré Woromogo, Stéphanie Inesse Garoua-Adjou, Ange Donatien Ngouyombo, Rodrigue Herman Doyama-Woza, Henri Saint Calvaire Diemer, Jean de Dieu Longo   +5 more
doaj   +2 more sources

Current Gaps in Survey Design and Analysis for Molecular Xenomonitoring of Vector-Borne Neglected Tropical Diseases: A Systematic Review. [PDF]

Trop Med Int Health
ABSTRACT Objectives Molecular xenomonitoring is a surveillance method for vector‐borne diseases where vectors are tested for molecular pathogen markers. Testing is typically on pools (groups) of vectors. Molecular xenomonitoring is a sensitive and efficient complement to human‐based surveillance.
McLure A, Alamnia T, Xu Z, Lau CL, Mayfield HJ.   +4 more
europepmc   +2 more sources

Epidemiological assessment of onchocerciasis in previously unmapped villages for ivermectin distribution in Fer-Fer District, Somali Regional State, Eastern Ethiopia [PDF]

BMC Infectious Diseases
Background Onchocerciasis is endemic to parts of Ethiopia; however, epidemiological data are lacking in some regions. This study aimed to assess the prevalence, intensity, and risk factors of onchocerciasis in previously unmapped villages in the Fer-Fer ...
Dek Kahin Yosef, Barwaqo Saleban Awil, Ahmed Saeed Ismail, Mohamed Ahmed Hassan   +3 more
doaj   +2 more sources

The Spectrum of Ocular Diseases in the Onchocerciasis-Endemic Focus of Raga in South Sudan [PDF]

Research and Reports in Tropical Medicine
Kenneth Lado Sube,1 Joseph Daniel Wani Lako,2 Justin Bruno Tongun,3 Tatjana Gerber,4 Jurel Payii Mamur,4 Sekonjo Juliano Hamid Moto,4 Stephen Raimon Legge Jada,5 Joseph Nelson Siewe Fodjo,6 Adrian Dennis Hopkins,7 Charles D Mackenzie,8,9 Robert ...
Sube KL, Lako JDW, Tongun JB, Gerber T, Mamur JP, Hamid Moto SJ, Jada SRL, Siewe Fodjo JN, Hopkins AD, Mackenzie CD, Colebunders R   +10 more
doaj   +2 more sources

Health-related quality of life and associated factors among Onchocerciasis patients in southeast Nigeria: A cross-sectional comparative study

PLoS Neglected Tropical Diseases, 2022
Introduction Onchocerciasis, a neglected tropical disease of public health importance, causes chronic morbidity and severe disability that may impact on health-related quality of life (HRQoL) of the infected people.
Adah E. Otache, Ifeyinwa L. Ezenwosu, Edmund N. Ossai, Elias C. Aniwada, Emmanuel A. Nwobi, Benjamin SC. Uzochukwu   +5 more
doaj   +2 more sources

Impact of a bi-annual community-directed treatment with ivermectin programme on the incidence of epilepsy in an onchocerciasis-endemic area of Mahenge, Tanzania: A population-based prospective study

PLoS Neglected Tropical Diseases, 2023
Background Community-directed treatment with ivermectin (CDTi) is used to eliminate onchocerciasis. However, despite 25 years of annual CDTi in Mahenge, Tanzania, the prevalence of onchocerciasis and onchocerciasis-associated epilepsy remained high in ...
D. Bhwana, Luís-Jorge Amaral, Athanas D. Mhina, Paul Matine, F. Francis, J. S. Siewe Fodjo, B. Mmbando, R. Colebunders   +7 more
semanticscholar   +1 more source

The prevalence of onchocerciasis in Africa and Yemen, 2000–2018: a geospatial analysis

BMC Medicine, 2022
Onchocerciasis is a disease caused by infection with Onchocerca volvulus, which is transmitted to humans via the bite of several species of black fly, and is responsible for permanent blindness or vision loss, as well as severe skin disease ...
Chris A. Schmidt, Elizabeth A. Cromwell, Elex Hill, Katie M. Donkers, Megan F Schipp, Kimberly B Johnson, D. Pigott, Chris A. Elizabeth A. Elex David M. Jaffar Victor Olatun Schmidt Cromwell Hill Pigott Abbas Adekanmbi Adeto, Chris A. Schmidt, Elizabeth A. Cromwell, Elex Hill, D. Pigott, Jaffar Abbas, Victor Adekanmbi, O. Adetokunboh, M. Ahmed, Fahad Mashhour Alanezi, Turki M. Alanzi, V. Alipour, C. Andrei, Tudorel Andrei, Davood Anvari, Seth Christopher Yaw Appiah, M. Aqeel, J. Arabloo, M. A. Jafarabadi, M. Ausloos, A. Baig, Maciej Banach, T. Bärnighausen, Krittika Bhattacharyya, Z. Bhutta, Ali Bijani, O. Brady, N. Bragazzi, Z. Butt, F. Carvalho, Vijay Kumar Chattu, Saad M A Dahlawi, G. Damiani, F. M. Demeke, Kebede Deribe, S. Dharmaratne, Daniel Diaz, Alireza Didarloo, Lucas Earl, M. Zaki, M. El Tantawi, N. Fattahi, E. Fernandes, N. Foigt, M. Foroutan, R. C. Franklin, Yuming Guo, Arvin Haj-Mirzaian, S. Hamidi, H. Hassankhani, C. Herteliu, T. Higazi, M. Hosseini, M. Hosseinzadeh, Mowafa J Househ, O S Ilesanmi, I. Ilic, M. Ilic, S. Irvani, Ravi Prakash Jha, John S Ji, J. Jonas, J. Jozwiak, Leila R. Kalankesh, Naser Kamyari, B. K. Matin, S. Karimi, G. Kayode, Ali Kazemi Karyani, E. Khan, Md Nuruzzaman Khan, Khaled Khatab, M. Khater, Neda Kianipour, Y. Kim, S. Kosen, D. Kusuma, C. la Vecchia, V. Lansingh, P. H. Lee, Shanshan Li, S. Maleki, M. Mansournia, F. R. Martins-Melo, C. McAlinden, W. Mendoza, T. Meštrović, M. Moghadaszadeh, A. Mohammadian-Hafshejani, S. Mohammadi, S. Mohammed, R. Moradzadeh, Paula Moraga, M. Naderi, Ahamarshan Jayaraman Nagarajan, I. Negoi, C. Nguyen, Huong Lan Thi Nguyen, Bogdan Oancea, A. Olagunju, A. Bali, O. Onwujekwe, A. Pana, V. Rahimi-Movaghar, K. Ramezanzadeh, D. Rawaf, S. Rawaf, Reza Rawassizadeh, A. Rezapour, A. I. Ribeiro, A. Samy, M. Shaikh, K. Sharafi, Aziz Sheikh, Jasvinder A. Singh, Eirini Skiadaresi, Shahin Soltani, W. Stolk, M. Sufiyan, A. Thomson, B. Tran, Khanh B. Tran, B. Unnikrishnan, F. Violante, G. Vu, Tomohide Yamada, S. Yaya, Paul Yip, N. Yonemoto, Chuanhua Yu, Yong Yu, M. Zamanian, Yunquan Zhang, Zhi-Jiang Zhang, A. Ziapour, Simon Iain Hay, Simon Iain Hay   +143 more
semanticscholar   +1 more source