Results 21 to 30 of about 11,493 (199)

Nodding syndrome research, lessons learned from the NSETHIO project

Cambridge Prisms: Global Mental Health, 2019
Background.Until recently, nodding syndrome (NS) was considered as a mysterious disease of unknown etiology. A link between onchocerciasis and epilepsy was suspected for a long time.
D. Geelhand de Merxem, J. N. Siewe Fodjo, S. Menon, A. Hotterbeekx, R. Colebunders   +4 more
doaj   +1 more source

Diagnosis of O. volvulus infection via skin exposure to diethylcarbamazine: clinical evaluation of a transdermal delivery technology-based patch

Parasites & Vectors, 2015
Background Elimination of onchocerciasis in Africa is now regarded as an achievable goal in many areas. This makes monitoring changes in infection prevalence a key component of control programmes. Monitoring is currently based on determining the presence
K. Awadzi, Nicholas O. Opoku, Simon K. Attah, Janis K. Lazdins-Helds, Annette C. Kuesel   +4 more
doaj   +1 more source

Elimination of onchocerciasis in Africa by 2025: an ambitious target requires ambitious interventions

Infectious Diseases of Poverty, 2019
To achieve the elimination of onchocerciasis transmission in all African countries will entail enormous challenges, as has been highlighted by the active discussion around onchocerciasis intervention strategies and evaluation procedures in this journal ...
Robert Colebunders, Wilma A. Stolk, Joseph Nelson Siewe Fodjo, Charles D. Mackenzie, Adrian Hopkins   +4 more
doaj   +1 more source

Evaluation of Lymphatic Filariasis and Onchocerciasis in Three Senegalese Districts Treated for Onchocerciasis with Ivermectin.

PLoS Neglected Tropical Diseases, 2016
In Africa, onchocerciasis and lymphatic filariasis (LF) are co-endemic in many areas. Current efforts to eliminate both diseases are through ivermectin-based mass drug administration (MDA).
Nana O Wilson, Alioune Badara Ly, Vitaliano A Cama, Paul T Cantey, Daniel Cohn, Lamine Diawara, Abdel Direny, Mawo Fall, Karla R Feeser, LeAnne M Fox, Achille Kabore, Amadou F Seck, Ngayo Sy, Daouda Ndiaye, Christine Dubray   +14 more
doaj   +1 more source

Is onchocerciasis elimination in Africa feasible by 2025: a perspective based on lessons learnt from the African control programmes

Infectious Diseases of Poverty, 2018
Background Onchocerciasis is found predominantly in Africa where large scale vector control started in 1974. Registration and donation of ivermectin by Merck & Co in 1987 enabled mass treatment with ivermectin in all endemic countries in Africa and the ...
Yankum Dadzie, Uche V. Amazigo, Boakye A. Boatin, Azodoga Sékétéli   +3 more
doaj   +1 more source

Current perspective of new anti-Wolbachial and direct-acting macrofilaricidal drugs as treatment strategies for human filariasis

GMS Infectious Diseases, 2022
Filarial diseases like lymphatic filariasis and onchocerciasis belong to the Neglected Tropical Diseases and remain a public health problem in endemic countries.
Ehrens, Alexandra, Hoerauf, Achim, Hübner, Marc P.   +2 more
doaj   +1 more source

Burden of onchocerciasis-associated epilepsy: first estimates and research priorities

Infectious Diseases of Poverty, 2018
Background Since the 1990s, evidence has accumulated of an increased prevalence of epilepsy in onchocerciasis-endemic areas in Africa as compared to onchocerciasis-free areas.
Natalie V. S. Vinkeles Melchers, Sarah Mollenkopf, Robert Colebunders, Michael Edlinger, Luc E. Coffeng, Julia Irani, Trésor Zola, Joseph N. Siewe, Sake J. de Vlas, Andrea S. Winkler, Wilma A. Stolk   +10 more
doaj   +1 more source

Stigma and epilepsy in onchocerciasis-endemic regions in Africa: a review and recommendations from the onchocerciasis-associated epilepsy working group

Infectious Diseases of Poverty, 2019
Background In onchocerciasis-endemic areas, particularly in those with a sub-optimal onchocerciasis control programme, a high prevalence of epilepsy is observed. Both onchocerciasis and epilepsy are stigmatizing conditions.
Sarah O’Neill, Julia Irani, Joseph Nelson Siewe Fodjo, Denis Nono, Catherine Abbo, Yasuaki Sato, Augustine Mugarura, Housseini Dolo, Maya Ronse, Alfred K. Njamnshi, Robert Colebunders   +10 more
doaj   +1 more source

Onchocerciasis control in Ghana (1974–2016)

Parasites & Vectors, 2021
Background The control of onchocerciasis in Ghana started in 1974 under the auspices of the Onchocerciasis Control Programme (OCP). Between 1974 and 2002, a combination of approaches including vector control, mobile community ivermectin treatment, and ...
Nana-Kwadwo Biritwum, Dziedzom K. de Souza, Odame Asiedu, Benjamin Marfo, Uche Veronica Amazigo, John Owusu Gyapong   +5 more
doaj   +1 more source

Advancing a Human Onchocerciasis Vaccine From Antigen Discovery to Efficacy Studies Against Natural Infection of Cattle With Onchocerca ochengi

Frontiers in Cellular and Infection Microbiology, 2022
Human onchocerciasis is a devastating neglected tropical disease caused by infection of the filarial nematode Onchocerca volvulus. The infection can cause irreversible visual impairment or blindness and stigmatizing dermatitis.
Bin Zhan, Maria Elena Bottazzi, Peter J. Hotez, Sara Lustigman   +3 more
doaj   +1 more source