Results 21 to 30 of about 18,093 (248)
High infection rates for onchocerciasis and soil-transmitted helminthiasis in children under five not receiving preventive chemotherapy: a bottleneck to elimination
Infectious Diseases of Poverty, 2022 Background The current mainstay for control/elimination of onchocerciasis and soil-transmitted helminthiasis (STH) relies on ivermectin- and mebendazole/albendazole-based preventive chemotherapies.H. Nana-Djeunga, Linda Djune-Yemeli, A. Domché, Cyrille Donfo-Azafack, Arnauld Efon-Ekangouo, Cédric G Lenou-Nanga, Narcisse Nzune-Toche, Yves Aubin Balog, J. Bopda, Stève Mbickmen-Tchana, Tirumalaisamy P. Velavan, Véronique Penlap-Beng, F. Ntoumi, J. Kamgno +13 moresemanticscholar +1 more sourceThe Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review. [PDF]
Health Sci RepABSTRACT Background and Aims
Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.Mutsaka-Makuvaza MJ, Binuyo MO, Cyuzuzo C, Igizeneza A, Sinumvayo JP, Ajakaye OG, Enabulele EE, Chinwadzimba Z, Agwu E, Midzi N. +9 moreeuropepmc +2 more sourcesDevelopment of emodepside as a possible adulticidal treatment for human onchocerciasis—The fruit of a successful industrial–academic collaboration
PLoS Pathogens, 2021 Current mass drug administration (MDA) programs for the treatment of human river blindness (onchocerciasis) caused by the filarial worm Onchocerca volvulus rely on ivermectin, an anthelmintic originally developed for animal health.J. Krücken, L. Holden-Dye, J. Keiser, R. Prichard, S. Townson, Benjamin L. Makepeace, M. Hübner, S. Hahnel, Ivan Scandale, A. Harder, D. Kulke +10 moresemanticscholar +1 more sourceHigh Prevalence of Epilepsy in an Onchocerciasis-Endemic Area in Mvolo County, South Sudan: A Door-To-Door Survey
Pathogens, 2021 In June 2020, a door-to-door household survey was conducted in Mvolo County, an onchocerciasis-endemic area in South Sudan. A total of 2357 households containing 15,699 individuals agreed to participate in the study.S. Raimon, Alfred Dusabimana, G. Abd-Elfarag, Samuel Okaro, J. Carter, C. Newton, M. Y. Logora, R. Colebunders +7 moresemanticscholar +1 more sourceWhy onchocerciasis transmission persists after 15 annual ivermectin mass drug administrations in South-West Cameroon
BMJ Global Health, 2021 Introduction Onchocerciasis is targeted for elimination mainly with annual community-directed treatment with ivermectin (CDTI). High infection levels have been reported in South-West Cameroon, despite ≥15 years of CDTI.Armelle Forrer, S. Wanji, Elisabeth Dibando Obie, T. Nji, L. Hamill, Kim Ozano, Helen Piotrowski, L. Dean, A. Njouendou, Relindis Ekanya, Winston Patrick Chounna Ndongmo, Ebua Gallus Fung, Dum-Buo Nnamdi, Raphael A Abong, Amuam Andrew Beng, Mathias Esum Eyong, Bertrand L Ndzeshang, Desmond Akumtoh Nkimbeng, Samuel Teghen, Anicetus Suireng, Ernerstine Ebot Ashu, Emmanuel Kah, Michele M Murdoch, Rachael Thomson, S. Theobald, P. Enyong, J. Turner, M. Taylor +27 moresemanticscholar +1 more sourceComputational Design and Preliminary Serological Analysis of a Novel Multi-Epitope Vaccine Candidate Against Onchocerciasis and Related Filarial Diseases
Pathogens, 2021 Onchocerciasis is a skin and eye disease that exerts a heavy socio-economic burden, particularly in sub-Saharan Africa, a region which harbours greater than 96% of either infected or at-risk populations.R. A. Shey, S. Ghogomu, C. M. Shintouo, Francis N. Nkemngo, D. N. Nebangwa, K. Esoh, Ntang Emmaculate Yaah, Muyanui Manka'aFri, Joel Ebai Nguve, Roland Akwelle Ngwese, F. Njume, Fru Asa Bertha, L. Ayong, R. Njemini, L. Vanhamme, J. Souopgui +15 moresemanticscholar +1 more sourcePredicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning
PLoS Neglected Tropical Diseases, 2021 Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across E. Cromwell, Joshua C. P. Osborne, T. Unnasch, M. Basáñez, K. Gass, Kira A Barbre, Elex Hill, Kimberly B Johnson, Katie M. Donkers, S. Shirude, Christopher A Schmidt, V. Adekanmbi, O. Adetokunboh, M. Afarideh, E. Ahmadpour, M. Ahmed, T. Akalu, Z. Al-Aly, Fahad Mashhour Alanezi, Turki M. Alanzi, V. Alipour, C. Andrei, F. Ansari, Mustafa Geleto Ansha, Davood Anvari, Seth Christopher Yaw Appiah, J. Arabloo, B. Arnold, M. Ausloos, M. Ayanore, A. Baig, M. Banach, A. Barać, T. Bärnighausen, M. Bayati, Krittika Bhattacharyya, Z. Bhutta, S. Bibi, Ali Bijani, S. Bohlouli, Mahdi Bohluli, O. Brady, N. Bragazzi, Z. Butt, F. Carvalho, Sirshendu Chatterjee, Vijay Kumar Chattu, Soosanna Kumary Chattu, N. Cormier, Saad M A Dahlawi, G. Damiani, Farah Daoud, A. Darwesh, A. Daryani, Kebede Deribe, S. Dharmaratne, Daniel Diaz, H. Do, M. El Sayed Zaki, M. El Tantawi, Demelash Abewa Elemineh, A. Faraj, M. Fasihi Harandi, Yousef Fatahi, V. Feigin, E. Fernandes, N. Foigt, M. Foroutan, R. Franklin, M. I. Gubari, D. Guido, Yuming Guo, Arvin Haj-Mirzaian, Kanaan Hamagharib Abdullah, S. Hamidi, C. Herteliu, Hagos Degefa de Hidru, T. Higazi, Naznin Hossain, M. Hosseinzadeh, M. Househ, O S Ilesanmi, M. Ilic, I. Ilic, Usman Iqbal, S. Irvani, Ravi Prakash Jha, F. Joukar, J. Jozwiak, Z. Kabir, Leila R. Kalankesh, R. Kalhor, B. Karami Matin, S. Karimi, A. Kasaeian, T. Kavetskyy, G. Kayode, Ali Kazemi Karyani, A. G. Kelbore, Maryam Keramati, Rovshan Khalilov, E. Khan, Md Nuruzzaman Khan, K. Khatab, M. Khater, Neda Kianipour, K. T. Kibret, Y. Kim, S. Kosen, Kristopher J. Krohn, D. Kusuma, C. la Vecchia, V. Lansingh, P. Lee, K. E. LeGrand, Shanshan Li, J. Longbottom, H. Magdy Abd El Razek, Muhammed Magdy Abd El Razek, A. Maleki, A. Mamun, A. Manafi, N. Manafi, M. Mansournia, F. R. Martins-Melo, M. Mazidi, C. McAlinden, Birhanu Geta Meharie, W. Mendoza, E. Mengesha, D. T. Mengistu, S. T. Mereta, T. Meštrović, T. Miller, M. Miri, M. Moghadaszadeh, A. Mohammadian-Hafshejani, R. Mohammadpourhodki, S. Mohammed, Salahuddin Mohammed, M. Moradi, R. Moradzadeh, Paula Moraga, J. Mosser, M. Naderi, Ahamarshan Jayaraman Nagarajan, G. Naik, I. Negoi, C. Nguyen, H. Nguyen, T. H. Nguyen, Rajan Nikbakhsh, Bogdan Oancea, T. Olagunju, A. Olagunju, Ahmed Omar Bali, O. Onwujekwe, A. Pana, H. Pourjafar, F. Rahim, Mohammad Hifz Ur Rahman, P. Rathi, S. Rawaf, D. Rawaf, Reza Rawassizadeh, S. Resnikoff, M. Reta, A. Rezapour, Enrico Rubagotti, S. Rubino, E. Sadeghi, A. Saghafipour, S. M. Sajadi, A. Samy, R. Sarmiento-Suárez, M. Sawhney, Megan F Schipp, A. Shaheen, M. Shaikh, M. Shamsizadeh, K. Sharafi, Aziz Sheikh, B. Shetty, J. Shin, K. M. Shivakumar, B. Simonetti, Jasvinder A. Singh, Eirini Skiadaresi, A. Soheili, Shahin Soltani, E. Spurlock, M. Sufiyan, T. Tabuchi, Leili Tapak, Robert L. Thompson, A. Thomson, Eugenio Traini, B. Tran, I. Ullah, Saif Ullah, C. Uneke, B. Unnikrishnan, O. Uthman, Natalie V. S. Vinkeles Melchers, F. Violante, H. F. Wolde, Tewodros Eshete Wonde, Tomohide Yamada, S. Yaya, Vahid Yazdi-Feyzabadi, Paul S. F. Yip, N. Yonemoto, Hebat-Allah S. A. Yousof, Chuanhua Yu, Yong Yu, H. Yusefzadeh, Leila Zaki, S. Zaman, M. Zamanian, Zhi-Jiang Zhang, Yunquan Zhang, A. Ziapour, Simon Iain Hay, D. Pigott +223 moresemanticscholar +1 more sourceThe burden of skin disease and eye disease due to onchocerciasis in countries formerly under the African Programme for Onchocerciasis Control mandate for 1990, 2020, and 2030
PLoS Neglected Tropical Diseases, 2021 Background Onchocerciasis (“river blindness”) can cause severe morbidity, including vision loss and various skin manifestations, and is targeted for elimination using ivermectin mass drug administration (MDA).Natalie V. S. Vinkeles Melchers, W. Stolk, W. van Loon, Bélen Pedrique, R. Bakker, M. Murdoch, S. D. de Vlas, L. Coffeng +7 moresemanticscholar +1 more source
