Results 21 to 30 of about 28,700 (244)

The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.
Mutsaka-Makuvaza MJ, Binuyo MO, Cyuzuzo C, Igizeneza A, Sinumvayo JP, Ajakaye OG, Enabulele EE, Chinwadzimba Z, Agwu E, Midzi N.   +9 more
europepmc   +2 more sources

The Prevalence of Onchocerciasis-Associated Epilepsy in Mundri West and East Counties, South Sudan: A Door-to-Door Survey

Pathogens, 2022
A two-phase survey of epilepsy was conducted in selected villages in Mundri West and East Counties (26 June–8 July, 2021), an onchocerciasis-endemic area in Western Equatoria State in South Sudan.
S. Jada, Alfred Dusabimana, G. Abd-Elfarag, Samuel Okaro, N. Brusselaers, J. Carter, M. Y. Logora, J. Rovarini, C. Newton, R. Colebunders   +9 more
semanticscholar   +1 more source

Onchocerciasis: Current knowledge and future goals

Frontiers in Tropical Diseases, 2022
Human Onchocerciasis, caused by infection by the filarial nematode Onchocerca volvulus, is a neglected public health disease that affects millions of people in the endemic regions of sub-Saharan Africa and Latin America. It is also called river blindness
Luisa Frallonardo, Francesco Di Gennaro, G. Panico, Roberta Novara, Elisabetta Pallara, Sergio Cotugno, Giacomo Guido, Elda De Vita, A. Ricciardi, Valentina Totaro, Michele Camporeale, G. De Iaco, D. Bavaro, Rossana Lattanzio, Giulia Patti, G. Brindicci, Roberta Papagni, C. Pellegrino, C. Santoro, F. Segala, G. Putoto, E. Nicastri, A. Saracino   +22 more
semanticscholar   +1 more source

A cross-sectional study of Simulium damnosum sensu lato breeding sites and species distribution in Sudan savanna, mixed savanna–forest and rainforest regions in Cameroon

Parasites & Vectors, 2022
Background The presence of breeding sites and distribution of species of Simulium damnosum sensu lato are critical in understanding the epidemiology of onchocerciasis and evaluating the impact of elimination interventions.
Franklin Ayisi, Naniogué Sedou, Stephanie Kouahou Dieunang, Florent Yaya, Edmond François Tchago, Cosmas Ejong Ndellejong, Benjamin Biholong, Daniel Adjei Boakye   +7 more
doaj   +1 more source

High infection rates for onchocerciasis and soil-transmitted helminthiasis in children under five not receiving preventive chemotherapy: a bottleneck to elimination

Infectious Diseases of Poverty, 2022
Background The current mainstay for control/elimination of onchocerciasis and soil-transmitted helminthiasis (STH) relies on ivermectin- and mebendazole/albendazole-based preventive chemotherapies.
H. Nana-Djeunga, Linda Djune-Yemeli, A. Domché, Cyrille Donfo-Azafack, Arnauld Efon-Ekangouo, Cédric G Lenou-Nanga, Narcisse Nzune-Toche, Yves Aubin Balog, J. Bopda, Stève Mbickmen-Tchana, Tirumalaisamy P. Velavan, Véronique Penlap-Beng, F. Ntoumi, J. Kamgno   +13 more
semanticscholar   +1 more source

A research and development agenda for the control and elimination of human helminthiases [PDF]

, 2012
<p>Background: Filarial nematodes are tissue-dwelling parasites that can be killed by Th2-driven immune effectors, but that have evolved to withstand immune attack and establish chronic infections by suppressing host immunity. As a consequence, the
Utzinger, J.
core   +10 more sources

High Prevalence of Epilepsy in an Onchocerciasis-Endemic Area in Mvolo County, South Sudan: A Door-To-Door Survey

Pathogens, 2021
In June 2020, a door-to-door household survey was conducted in Mvolo County, an onchocerciasis-endemic area in South Sudan. A total of 2357 households containing 15,699 individuals agreed to participate in the study.
S. Raimon, Alfred Dusabimana, G. Abd-Elfarag, Samuel Okaro, J. Carter, C. Newton, M. Y. Logora, R. Colebunders   +7 more
semanticscholar   +1 more source

Development of emodepside as a possible adulticidal treatment for human onchocerciasis—The fruit of a successful industrial–academic collaboration

PLoS Pathogens, 2021
Current mass drug administration (MDA) programs for the treatment of human river blindness (onchocerciasis) caused by the filarial worm Onchocerca volvulus rely on ivermectin, an anthelmintic originally developed for animal health.
J. Krücken, L. Holden-Dye, J. Keiser, R. Prichard, S. Townson, Benjamin L. Makepeace, M. Hübner, S. Hahnel, Ivan Scandale, A. Harder, D. Kulke   +10 more
semanticscholar   +1 more source

Management of onchocerciasis among adolescents in nkwanta north district of Ghana: Qualitative study of adolescents' perception, community and health system support.

PLoS Neglected Tropical Diseases, 2023
BackgroundOnchocerciasis affects the quality of life to a greater extent among affected individuals. The World Health Organization (WHO)'s Onchocerciasis Control Program (OCP) has effectively reduced the prevalence of onchocerciasis by interrupting the ...
Sitsofe Gbogbo, Hubert Amu, Robert Kokou Dowou, Martin Amogre Ayanore   +3 more
doaj   +1 more source

Why onchocerciasis transmission persists after 15 annual ivermectin mass drug administrations in South-West Cameroon

BMJ Global Health, 2021
Introduction Onchocerciasis is targeted for elimination mainly with annual community-directed treatment with ivermectin (CDTI). High infection levels have been reported in South-West Cameroon, despite ≥15 years of CDTI.
Armelle Forrer, S. Wanji, Elisabeth Dibando Obie, T. Nji, L. Hamill, Kim Ozano, Helen Piotrowski, L. Dean, A. Njouendou, Relindis Ekanya, Winston Patrick Chounna Ndongmo, Ebua Gallus Fung, Dum-Buo Nnamdi, Raphael A Abong, Amuam Andrew Beng, Mathias Esum Eyong, Bertrand L Ndzeshang, Desmond Akumtoh Nkimbeng, Samuel Teghen, Anicetus Suireng, Ernerstine Ebot Ashu, Emmanuel Kah, Michele M Murdoch, Rachael Thomson, S. Theobald, P. Enyong, J. Turner, M. Taylor   +27 more
semanticscholar   +1 more source