Results 31 to 40 of about 18,093 (248)

Reducing onchocerciasis-associated morbidity in onchocerciasis-endemic foci with high ongoing transmission: a focus on the children.

International Journal of Infectious Diseases, 2022
Efforts are being directed toward the elimination of onchocerciasis transmission in endemic areas with community-directed treatment with ivermectin (CDTI) in Africa, which greatly reduces onchocerciasis-associated disease. However, onchocerciasis remains
Robert Colebunders, Christoph Kaiser, Maria-Gloria Basáñez, Piero Olliaro, Tom Lakwo, Joseph Nelson Siewe Fodjo   +5 more
doaj   +1 more source

In-silico design of a multi-epitope vaccine candidate against onchocerciasis and related filarial diseases

Scientific Reports, 2019
Onchocerciasis is a parasitic disease with high socio-economic burden particularly in sub-Saharan Africa. The elimination plan for this disease has faced numerous challenges. A multi-epitope prophylactic/therapeutic vaccine targeting the infective L3 and
R. A. Shey, S. Ghogomu, K. Esoh, Neba Derrick Nebangwa, C. M. Shintouo, Nkemngo Francis Nongley, B. F. Asa, Ferdinand Njume Ngale, L. Vanhamme, J. Souopgui   +9 more
semanticscholar   +1 more source

Prevalence and incidence of nodding syndrome and other forms of epilepsy in onchocerciasis-endemic areas in northern Uganda after the implementation of onchocerciasis control measures

Infectious Diseases of Poverty, 2020
Background Around 2007, a nodding syndrome (NS) epidemic appeared in onchocerciasis-endemic districts of northern Uganda, where ivermectin mass distribution had never been implemented.
Nolbert Gumisiriza, F. Mubiru, J. S. Siewe Fodjo, Martin Mbonye Kayitale, A. Hotterbeekx, R. Idro, Issa Makumbi, T. Lakwo, B. Opar, J. Kaducu, J. Wamala, R. Colebunders   +11 more
semanticscholar   +1 more source

Mansonella perstans, Onchocerca volvulus and Strongyloides stercoralis infections in rural populations in central and southern Togo

Parasite Epidemiology and Control, 2018
Background: Mansonella perstans, Onchocerca volvulus and Strongyloides stercoralis are widespread helminth parasites in the tropics. Their distribution remains difficult to determine as it may change during national disease control programs and with ...
Francois Korbmacher, Kossi Komlan, Richard G. Gantin, Wiyao P. Poutouli, Koffi Padjoudoum, Potchoziou Karabou, Peter T. Soboslay, Carsten Köhler   +7 more
doaj   +1 more source

A Second Population-Based Cohort Study in Cameroon Confirms the Temporal Relationship Between Onchocerciasis and Epilepsy

Open Forum Infectious Diseases, 2020
To confirm our earlier evidence of a temporal and dose–response relationship between onchocerciasis and epilepsy, we conducted another cohort study in a different setting in Cameroon.
C. Chesnais, C. Bizet, Jérémy T. Campillo, W. Njamnshi, J. Bopda, P. Nwane, S. Pion, A. Njamnshi, M. Boussinesq   +8 more
semanticscholar   +1 more source

Progress towards onchocerciasis elimination in Côte d’Ivoire: A geospatial modelling study

PLoS Neglected Tropical Diseases, 2021
Background Côte d’Ivoire has had 45 years of intervention for onchocerciasis by vector control (from 1975 to 1991), ivermectin mass drug administration (MDA) (from 1992 to 1994) and community directed treatment with ivermectin (CDTi) from 1995 to the ...
Obiora A. Eneanya, B. Koudou, Méité Aboulaye, A. Elvis, Yeo Souleymane, Marie-Madeleine Kouakou, G. Weil, Peter U. Fischer   +7 more
semanticscholar   +1 more source

Human Onchocerciasis: Modelling the Potential Long-term Consequences of a Vaccination Programme. [PDF]

PLoS Neglected Tropical Diseases, 2015
BACKGROUND:Currently, the predominant onchocerciasis control strategy in Africa is annual mass drug administration (MDA) with ivermectin. However, there is a consensus among the global health community, supported by mathematical modelling, that ...
Hugo C Turner, Martin Walker, Sara Lustigman, David W Taylor, María-Gloria Basáñez   +4 more
doaj   +1 more source

The impact of ivermectin on onchocerciasis in villages co-endemic for lymphatic filariasis in an area of onchocerciasis recrudescence in Burkina Faso

PLoS Neglected Tropical Diseases, 2021
In Burkina Faso, onchocerciasis was no longer a public health problem when the WHO Onchocerciasis Control Programme in West Africa closed at the end in 2002. However, epidemiological surveillance carried out from November 2010 to February of 2011, showed
A. Nikiéma, L. Koala, A. Sondo, R. Post, Alain B Paré, C. Kafando, R. Kambire, B. Sow, C. Bougouma, R. Dabiré, S. Traoré   +10 more
semanticscholar   +1 more source

‘Slash and clear’ vector control for onchocerciasis elimination and epilepsy prevention: a protocol of a cluster randomised trial in Cameroonian villages

BMJ Open, 2021
Introduction Onchocerciasis, caused by the filarial nematode Onchocerca volvulus, remains endemic in Cameroon despite decades of community-directed treatment with ivermectin (CDTI).
J. S. Siewe Fodjo, M. Vieri, L. Ngarka, W. Njamnshi, L. Nfor, M. Mengnjo, A. Hendy, P. Enyong, Dennis Palmer, M. Basáñez, R. Colebunders, Alfred K. Njamnshi   +11 more
semanticscholar   +1 more source

The geographic distribution of onchocerciasis in the 20 participating countries of the African Programme for Onchocerciasis Control: (2) pre-control endemicity levels and estimated number infected

Parasites & Vectors, 2014
Background The original aim of the African Programme for Onchocerciasis Control (APOC) was to control onchocerciasis as a public health problem in 20 African countries.
Honorat GM Zouré, Mounkaila Noma, Afework H Tekle, Uche V Amazigo, Peter J Diggle, Emanuele Giorgi, Jan HF Remme   +6 more
doaj   +1 more source