Results 31 to 40 of about 384,141 (378)
Cells, 2023 Hepatocellular carcinoma (HCC) is one of the most frequent cancers in humans, characterised by a high resistance to conventional chemotherapy, late diagnosis, and a high mortality rate.
Milena Krajnović +3 more
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Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells. [PDF]
, 2019 Lactate is a ubiquitous molecule in cancer. In this exploratory study, our aim was to test the hypothesis that lactate could function as an oncometabolite by evaluating whether lactate exposure modifies the expression of oncogenes, or genes encoding ...
Brooks, George A +4 more
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Ultrabright gap-enhanced Raman tags for high-speed bioimaging
Nature Communications, 2019 The speed of surface-enhanced Raman spectroscopy (SERS) imaging is generally limited due to low Raman signals. Here, the authors develop bright gap-enhanced Raman tags with external hot spots and demonstrate their use in fast near-infrared bioimaging.
Yuqing Zhang +4 more
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Molecules, 2021 Arsenic is considered a worldwide pollutant that can be present in drinking water. Arsenic exposure is associated with various diseases, including cancer.
María Elena Camacho-Moll +9 more
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eLife, 2015 Human lung adenocarcinomas (LUAD) contain mutations in EGFR in ∼15% of cases and in KRAS in ∼30%, yet no individual adenocarcinoma appears to carry activating mutations in both genes, a finding we have confirmed by re-analysis of data from over 600 LUAD.
Arun M Unni +4 more
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Gastrointestinal Tumors: Phytochemical and Drug Combinations Targeting the Hallmarks of Cancer
Applied Sciences, 2021 Cancer is a worldwide burden resulting in millions of deaths each year. In particular, gastrointestinal tumors are life-threatening malignancies and one of the leading reasons for death in developed countries.
Emanuele Salvatore Scarpa +2 more
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Ageing And Cancer As Diseases Of Epigenesis [PDF]
, 2009 Cancer and ageing are often said to be diseases of development. During the past fifty years, the genetic components of cancer and ageing have been intensely investigated since development, itself, was seen to be an epiphenomenon of the genome.
Gilbert, Scott F.
core +2 more sources
Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS
Molecular Systems Biology, 2012 RAS mutations are highly relevant for progression and therapy response of human tumours, but the genetic network that ultimately executes the oncogenic effects is poorly understood.
Iwona Stelniec‐Klotz +8 more
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TMEM Proteins in Cancer: A Review
Frontiers in Pharmacology, 2018 A transmembrane protein (TMEM) is a type of protein that spans biological membranes. Many of them extend through the lipid bilayer of the plasma membrane but others are located to the membrane of organelles.
Kathleen Schmit, Carine Michiels
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Differentiated thyroid cancer: Growth factors, oncogenes and environmental influences [PDF]
Archive of Oncology, 2003 The present data of growth factors, oncogenes, tumor-suppressor-genes and environmental factors can be summarized in thus: thyrotropin, growth factors and other hormones do increase thyrocyte growth and specific mutations of growth factor receptors ...
Paunović Ivan R.
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