Results 111 to 120 of about 31,178 (269)
Journal of Applied Health Sciences, 2018 Malignant tumors are the most common cause of mortality in humans. Accumulation of mutation in cells causes uncontrolled cell division as well as prevention of their programmed cell death, leading to neoplastic changes. Tumor mass which avoids the immune response of the host, grows and spreads. Modern approach to malignant tumor therapy, which is still
Poljak, Ines, Korać, Petra
openaire +2 more sources
Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors
OncoImmunology, 2018 Oncolytic viruses selectively target and kill cancer cells in an immunogenic fashion, thus supporting the establishment of therapeutically relevant tumor-specific immune responses. In 2015, the US Food and Drug Administration (FDA) approved the oncolytic
Jonathan G. Pol +14 more
doaj +1 more source
Targeting an Oncolytic Influenza A Virus to Tumor Tissue by Elastase
Molecular Therapy: Oncolytics, 2017 Oncolytic viruses are currently established as a novel type of immunotherapy. The challenge is to safely target oncolytic viruses to tumors. Previously, we have generated influenza A viruses (IAVs) containing deletions in the viral interferon antagonist.
Irina Kuznetsova +10 more
doaj +1 more source
Improving oncolytic adenoviral therapies for gastrointestinal cancers and tumor initiating cells [PDF]
, 2010 Although the treatment of most cancers has improved steadily, only few metastatic solid tumors can be cured. Despite responses, refractory clones often emerge and the disease becomes refractory to available treatment modalities.
Kangasniemi, Lotta
core
Oncolytic vaccinia virus and cancer immunotherapy
Frontiers in ImmunologyOncolytic virotherapy (OVT) is a promising form of cancer treatment that uses genetically engineered viruses to replicate within cancer cells and trigger anti-tumor immune response.
Lihua Xu +5 more
doaj +1 more source
Advances in Oncolytic Viral Therapy in Melanoma: A Comprehensive Review
VaccinesCheckpoint inhibitor therapy revolutionized the treatment of patients with melanoma. However, in patients where melanoma exhibits resistance to checkpoint inhibitor therapy, the treatment options are limited.
Ayushi Garg +12 more
doaj +1 more source
Oncolytic viruses as therapeutic agents
Annals of Medicine, 2001 The concept of using viruses as oncolytic agents has a long history. However, relatively new developments are the use of these viruses as gene delivery vehicles and the restriction of viral replication and lysis to tumour cells. The latter is attempted by the use of tumour-specific promoters, which transcriptionally target viral genes involved in ...
openaire +2 more sources
Literature review: Virus and cancer [PDF]
, 2017 Traballo fin de grao (UDC.CIE). Bioloxía. Curso 2016/2017[Abstract] Cancer is one of the main causes of global mortality, and even though it is considered to be a non-communicable disease, several infectious agents have been found to contribute to ...
Carreira Santos, Sofía
core
Novel Chimeric Immuno-Oncolytic Virus CF33-hNIS-antiPDL1 for the Treatment of Pancreatic Cancer
, 2020 Yanghee Woo +9 more
openalex +2 more sources
Oncolytic Viruses: Now Interviewing for the All-Star Game [PDF]
, 2010 Richard G. Vile
openalex +1 more source