The investigation of oncolytic viruses in the field of cancer therapy. [PDF]
Yuan Z +17 more
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Oncolytic Viruses and Immunotherapy for the Treatment of Uveal Melanoma and Retinoblastoma: The Current Landscape and Novel Advances. [PDF]
Kulbay M +9 more
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Extracellular vesicles as missiles for enhanced anti-tumor efficacy of oncolytic viruses: from disseminating oncolysis and anti-tumor immunity to targeted delivery. [PDF]
Safarzadeh M +3 more
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Erratum: Advances in cell-based delivery of oncolytic viruses as therapy for lung cancer. [PDF]
Nia GE +4 more
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Oncolytic Viruses as Reliable Adjuvants in CAR-T Cell Therapy for Solid Tumors. [PDF]
Stilpeanu RI +3 more
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Optimizing Pancreatic Cancer Therapy: The Promise of Immune Stimulatory Oncolytic Viruses. [PDF]
Thoidingjam S +4 more
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miRNA-Mediated Mechanisms in the Generation of Effective and Safe Oncolytic Viruses. [PDF]
Toropko M, Chuvpilo S, Karabelsky A.
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Although the cytotoxic effects of viruses are usually viewed in terms of pathogenicity, it is possible to harness this activity for therapeutic purposes. Viral genomes are highly versatile, and can be modified to direct their cytotoxicity towards cancer cells. These viruses are known as oncolytic viruses.
Lynda K. Hawkins, David Kirn
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Oncolytic viruses: adenoviruses
Virus Genes, 2017Tumor-selectively replicating (oncolytic) viruses are promising tools for therapy of solid cancers and have been initially developed to achieve potent tumor lysis with acceptable side effects on healthy tissue. However, in recent years, oncolytic viruses have been recognized as therapeutic vehicles exhibiting multipronged anti-tumoral activity.
Julia Niemann, Florian Kühnel
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