Results 91 to 100 of about 19,011 (195)

IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M

Mediators of Inflammation, 2020
The interleukin-1 family member IL-33 participates in both innate and adaptive T helper-2 immune cell responses in models of lung disease. The IL-6-type cytokine Oncostatin M (OSM) elevates lung inflammation, Th2-skewed cytokines, alternatively activated
Fernando Botelho, Anisha Dubey, Ehab A. Ayaub, Rex Park, Ashley Yip, Allison Humbles, Roland Kolbeck, Carl D. Richards   +7 more
doaj   +1 more source

The role of cytokines in ovarian cancer drug resistance

International Journal of Cancer, Volume 158, Issue 4, Page 821-834, 15 February 2026.
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang, Yunxia Zang, Rebeka Dejenie, Junyuan Bing, Shixia Dong, Yanfei Zhang, Yi Zhu, Jingjing Li   +7 more
wiley   +1 more source

Establishment of pluripotent cell lines from vertebrate species - Present status and future prospects [PDF]

, 1999
Pluripotent embryonic stem (ES) cells are undifferentiated cell lines derived from early embryos and are capable of unlimited undifferentiated proliferation in vitro.
Prelle, Katja, Vassiliev, Ivan M., Vassilieva, Svetlana G., Wobus, Anna M., Wolf, Eckhard   +4 more
core   +1 more source

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

Advanced Science, Volume 13, Issue 12, 27 February 2026.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély, István Narozsny, Levente Szarka, Daniel V. Veres, Peter Csermely, Dávid Keresztes   +5 more
wiley   +1 more source

Combined Use of Fecal Biomarkers in Inflammatory Bowel Diseases: Oncostatin M and Calprotectin

Journal of Inflammation Research, 2021
Ying Cao,1,* Yibei Dai,1,* Lingyu Zhang,1 Danhua Wang,1 Wen Hu,2 Qiao Yu,3 Xuchu Wang,1 Pan Yu,1 Weiwei Liu,1 Ying Ping,1 Tao Sun,1 Yiwen Sang,1 Zhenping Liu,4 Yan Chen,3 Zhihua Tao1 1Department of Laboratory Medicine, Zhejiang University School ...
Cao Y, Dai Y, Zhang L, Wang D, Hu W, Yu Q, Wang X, Yu P, Liu W, Ping Y, Sun T, Sang Y, Liu Z, Chen Y, Tao Z   +14 more
doaj  

Human cytomegalovirus immediate-early 1 protein rewires upstream STAT3 to downstream STAT1 signaling switching an IL6-type to an IFNγ-like response [PDF]

, 2016
MN and CP were supported by the Wellcome Trust (www.wellcome.ac.uk) Institutional Strategic Support Fund and CP was supported by the Deutsche Forschungsgemeinschaft (PA 815/2-1; www.dfg.de).The human cytomegalovirus (hCMV) major immediate-early 1 protein
Thomas Harwardt, Simone Lukas, Marion Zenger, Tobias Reitberger, Daniela Danzer, Theresa Übner, Diane C. Munday, Michael Nevels, Christina Paulus, Robert F. Kalejta, S Abroun, JJ O'Shea, D Guschin, SJ Rodig, NC Reich, H Yu, F Schaper, B Carow, Y Yin, JR Teijaro, N Au-Yeung, I Najjar, B Saha, G Regis, AP Costa-Pereira, HH Ho, A Stephanou, P Kumari, RE Randall, C Richardson, T Knoblach, VH Wood, R Renne, M Chatterjee-Kishore, JE McLaren, WJ Liu, WY Chen, J McLaren, SV Kuchipudi, JM Reitsma, CA King, D Daigle, T Du, ER Hill, S Koganti, E Slinger, M Boeckh, P Griffiths, Y Cohen, E Mocarski, C Paulus, M Scherer, L Amsler, M Trilling, VT Le-Trilling, EE Marshall, JH Ahn, JM Gawn, RF Greaves, ES Mocarski, L Torres, C Paulus, S Krauss, YH Huh, M Scherer, S Müller, ML Spengler, M Nevels, J Reinhardt, RL Lafemina, GW Wilkinson, K Mücke, YE Kim, J Jaworska, JL Meier, A Kaptein, J Renneson, RT Taylor, EP Browne, G Chan, M Mezger, DN Streblow, J Dumortier, MC Cheeran, P Caposio, SP Gravel, K Lee, K Koh, E Beurel, M Shu, DJ Dauer, M Snyder, Q Lepiller, Y Xu, RD Everett, Y Lu, GP Hayhurst, AD Yurochko, MJ Margolis, Q Tang, M Reeves, JH Ahn, M Nevels, E Zalckvar, B Raghavan, B Strobl, PC Heinrich, N Stahl, U Hemmann, C Gerhartz, Y Qing, D Kamimura, HA Bluyssen, GR Gariano, T Li, F Dag, JK Holzki, MB Reeves, C Söderberg-Naucler, XF Liu, CA Biron, M Trilling, D Hargett, E Poole, MS Smith, E Poole, RD Everett, BK Tischer, H Zhu, S Hambleton, FL Graham, C Sinzger, M Umashankar, UK Laemmli, A Colson, K Mahboubi, RP Donnelly, BJ Grube, RR Schumann, MK Steiner, T Mohri, JH Lee, G Hoermann, SK Singh, SA Robertson, A Gazel, A Ito, A Okaya, L Zhang, A Dreuw, S Porter, H Wang, FM Rogerson, RI Nurieva, M Ciofani, Y Ikeda, F Blanchard, SL Turner, E Larrea, SR Walker, BJ Van Lenten, S Sawa, P Chakrabarty, MA Nowell, EJ Kim, JA van Roon, TG Boulton, CT Sherman, OA Timofeeva, Z Ni, BJ Jenkins, PA Croonquist, H Zhu, M Saito, JE Jung, F Xiao, D Zhang, D Maritano, M Ichiba, KN Khan, T Wuestefeld, TK Sengupta, M Tomida, AF Voronova, L Williams, O Kim, C Bovolenta, M Zemskova, F Zhang, JX Zhang   +189 more
core   +3 more sources

Clonal Haematopoiesis in Type 2 Diabetes: A Review of Mechanistic Links With Inflammation and Cardiovascular Disease

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 2, February 2026.
ABSTRACT Clonal haematopoiesis (CH) has been recognized as an important interface between chronic inflammation, metabolic dysfunction, and the heightened cardiovascular risk observed in type 2 diabetes (T2D). CH arises from somatic mutations that give haematopoietic stem cells a competitive advantage and drive the expansion of pro‐inflammatory myeloid ...
Ludovica Migliozzi, Marella Marassi, Mattia Albiero, Gian Paolo Fadini   +3 more
wiley   +1 more source

Proinflammatory biomarkers and platelet aggregation activity in patients with coronary artery disease

Бюллетень сибирской медицины
Aim. To determine concentrations and identify the relationship of biomarkers (endocan / cell-specific molecule-1, fatty acid binding protein 4 (FABP 4), placental growth factor (PlGF), oncostatin M), with parameters of collageninduced platelet ...
O. A. Trubacheva, I. V. Kologrivova, O. L. Schnaider, I. V. Petrova, V. N. Vasiliev, I. V. Kovalev, I. Yu. Yakimovich   +6 more
doaj   +1 more source

Heteroarylketones inhibit astroglial interleukin-6 expression via a STAT3/NF-κB signaling pathway [PDF]

, 2011
Background Elevated brain levels of the pleiotropic cytokine interleukin-6, which is mainly secreted from activated local astrocytes, contribute to pathological events including neuroinflammation and neurodegeneration. Thus, inhibition of pathological IL-
Ingo Schulz, Claudia Engel, André J Niestroj, Ulrike Zeitschel, Katja Menge, Astrid Kehlen, Antje Meyer, Steffen Roßner, Hans-Ulrich Demuth   +8 more
core   +1 more source

Indicators of endocrine function of muscle and fat tissue in athletes participating in martial arts

Спортивная медицина: наука и практика
Purpose of the study: the aim of that study was an investigation of the level of adipokines, myokines and growth factors in the blood of athletes involved in acyclic sports — martial arts.Materials and methods: we have investigated 15 male athletes aged ...
A. V. Shestopalov, V. V. Davydov, K. P. Merkel, T. V. Grigoryeva, D. S. Martykanova, N. Сh. Davletova, A. V. Laikov, S. A. Roumiantsev   +7 more
doaj   +1 more source