Results 11 to 20 of about 21,326 (236)

Oncostatin M Modulation of Lipid Storage [PDF]

Biology, 2015
Oncostatin M (OSM) is a cytokine belonging to the gp130 family, whose members serve pleiotropic functions. However, several actions of OSM are unique from those of other gp130 cytokines, and these actions may have critical roles in inflammatory ...
Carrie M. Elks, Jacqueline M. Stephens
doaj   +3 more sources

Oncostatin M promotes lipolysis in white adipocytes

Adipocyte, 2022
Oncostatin M (OSM) is a member of the glycoprotein 130 cytokine family that is involved in chronic inflammation and increased in adipose tissue under obesity and insulin resistance. OSM was shown to inhibit adipogenesis, suppress browning, and contribute
Pim P. van Krieken, Julian Roos, Pamela Fischer-Posovszky, Stephan Wueest, Daniel Konrad   +4 more
doaj   +3 more sources

The therapeutic potential of targeting Oncostatin M and the interleukin-6 family in retinal diseases: A comprehensive review [PDF]

Open Life Sciences
Retinal diseases, which can lead to significant vision loss, are complex conditions involving various cellular and molecular mechanisms. The interleukin-6 (IL-6) family, particularly Oncostatin M (OSM), has garnered attention for their roles in retinal ...
Mori Tommaso, Nagaraj Nareshkumar Ragavachetty, Surico Pier Luigi, Zhou Wenjing, Parmar Uday Pratap Singh, D’Esposito Fabiana, Gagliano Caterina, Musa Mutali, Zeppieri Marco   +8 more
doaj   +2 more sources

The IL-22-oncostatin M axis promotes intestinal inflammation and tumorigenesis. [PDF]

Nat Immunol
Cineus R, Luo Y, Saliutina M, Manna S, Cancino CA, Velasco Blázquez L, Wang L, Bösel D, Abdelrahman A, Klementowicz JE, Scherl A, Hainbuch S, Bréart B, Kwon G, Konopka A, Guerra GM, von Coburg E, Gerbeth L, Roels J, Heinrich F, Müller N, Durek P, Deigendesch N, Ziai J, Hung J, Conrad T, TRR241 IBDome Consortium, Kühl AA, Wirtz S, Löhning M, Keir M, Diefenbach A, Mashreghi MF, Siegmund B, Schumann M, Romagnani C, West NR, Hegazy AN.   +37 more
europepmc   +3 more sources

Development of the First Small-Molecule Inhibitor Targeting Oncostatin M for Treatment of Breast Cancer. [PDF]

J Med Chem
Wolf CL, Feci A, Tuccinardi JP, Coughlin GH, Holdaway KA, Muhammed T, Pruett C, Lighter D, McGrath C, Engmann T, Pou-Torres M, Rushing B, Woodbury L, Haile SE, Scott H, Tawara K, Dinca S, Xu D, King MD, Warner LR, Jorcyk CL, Warner DL.   +21 more
europepmc   +2 more sources

Oncostatin M Measurement [PDF]

, 2020
National Cancer Institute
openalex   +2 more sources

Oncostatin-M functionalized cryogel microspheres for promoting diabetic bone defects regeneration [PDF]

J Orthop Translat
Song R, Yuan X, Wan Z, Zhang L, Rao F, Zhao Y, Yuan Z.   +6 more
europepmc   +2 more sources

“Comparative study of serum and synovial fluid Oncostatin M level in rheumatoid arthritis and osteoarthritis patients”

Journal of Radiation Research and Applied Sciences, 2022
Background: Rheumatoid arthritis (RA) remains a long-standing inflammatory syndrome where the joint synovial membrane is inflamed, with subsequent joint deformation. Osteoarthritis (OA) is considered to be a progressive destruction of articular cartilage
Iman H. Bassyouni, Dina F. Elessawi, Mohamed S. Tawfik, Neveen M. Nosseir   +3 more
doaj   +1 more source

Oncostatin M is a regulator of fibroblast growth factor 23 (FGF23) in UMR106 osteoblast-like cells

Scientific Reports, 2023
Renal phosphate and vitamin D metabolism is under the control of fibroblast growth factor 23 (FGF23), an endocrine and paracrine factor predominantly produced in bone. FGF23 formation is stimulated by active vitamin D, or parathyroid hormone (PTH), which
Sina Münz, Martina Feger, Michael Föller   +2 more
doaj   +1 more source

Thrombocytopoietic properties of oncostatin M [PDF]

Blood, 1995
Oncostatin M (OM) is a 28-kD glycoprotein that exhibits a panoply of biologic effects. Based on histologic observations of increased splenic megakaryocytes in nude mice implanted with an OM-secreting cell line, the thrombocytopoietic properties of OM in mice were investigated in culture and in vivo.
PM Wallace, JF MacMaster, J. A. Rillema, Jiao Peng, SA Burstein, M. Shoyab   +5 more
openalex   +3 more sources