Results 71 to 80 of about 2,310,170 (297)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Future Proofing Higher Education in the Pacific with Open and Flexible Learning

open access: yesJournal of Learning for Development, 2018
Affordable access to higher education is a major challenge for small Pacific island nations. The University of the South Pacific which is owned and governed by twelve island nations in this region plays a special role in meeting this challenge.
Som Naidu, Keith Roberts
doaj  

Posting Traditional Ecological Knowledge on Open Access Biodiversity Platforms: Implications for Learning Design

open access: yesThe Australian Journal of Indigenous Education, 2015
BowerBird is an open platform biodiversity website (http://www.BowerBird.org.au) and a nationally funded project under management of the Atlas of Living Australia (ALA) and Museum Victoria.
Johanna Funk   +2 more
doaj   +1 more source

Open defecation practice and its determinants among households in sub-Saharan Africa: pooled prevalence and multilevel analysis of 33 sub-Saharan Africa countries demographic and health survey

open access: yesTropical Medicine and Health, 2022
Background Open defecation facilitates the transmission of pathogens that cause diarrheal diseases, which is the second leading contributor to the global burden of disease.
Daniel Gashaneh Belay   +5 more
doaj   +1 more source

Open Education and the Sustainable Development Goals: Making Change Happen [PDF]

open access: yes, 2017
Education for All has been a concept at the heart of international development since 1990 and has found its latest instantiation within the Sustainable Development Goals (SDGs) as SDG 4, ‘Ensure inclusive and equitable quality education and promote ...
Lane, Andy
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An investigation into social learning activities by practitioners in open educational practices

open access: yesInternational Review of Research in Open and Distributed Learning, 2014
By investigating how educational practitioners participate in activities around open educational practices (OEP), this paper aims at contributing to an understanding of open practices and how these practitioners learn to use OEP.
Bieke Schreurs   +5 more
doaj   +3 more sources

Open Educational Practices mit, durch und trotz Open Educational Resources

open access: yesMedienPädagogik: Zeitschrift für Theorie und Praxis der Medienbildung
Der Beitrag thematisiert die Zusammenarbeit der Hochschulstandorte Siegen und Wuppertal im Rahmen des Projekts InDigO und ihre Gestaltung von Open Educational Practices (OEP) im Kontext inklusionsorientierter Lehrkräftebildung. Unter besonderer Betrachtung von Material und dessen Bedeutsamkeit im Hochschulkontext sowie Planungsprozessen im Kontext der ...
Alina Schulte-Buskase, Annika Gruhn
openaire   +3 more sources

Videobasiertes Lehr-Lernszenario in der Hochschule – theoretischer Hintergrund und struktureller Rahmen eines Praxisbeispiels zur Wertebildung

open access: yesBibliothek
Videobasierte Lehr-Lernszenarien bieten hervorragende Möglichkeiten, eine Brücke zur Praxis zu schlagen und die professionelle Wahrnehmung von Lernenden zu schulen.
Eckert Johanna, Zeelen Tim
doaj   +1 more source

Open Praxis, volume 10 issue 2

open access: yesOpen Praxis, 2018
For a fifth consecutive year, Open Praxis has partnered with the Open Education Consortium for the publication of selected papers among those presented in the 2018 Open Education Global Conference, held in Delft (The Netherlands) from 24 to 26 of April ...
Inés Gil-Jaurena (ed.), various authors
doaj   +1 more source

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