Results 71 to 80 of about 1,440,104 (391)

An open reading frame upstream from the nifH gene of Klebsiella pneumoniae [PDF]

open access: yes, 1983
An open reading frame upstream from nifHDK operon of Klebsiella pneumoniae had been described. The orientation of this open reading frame is opposite to that of nifHDK and sequence homology was found between the open reading frame promoter and the ...
Kong, Qiu-tong   +3 more
core  

Crystal structure of the 3C protease from South African Territories type 2 foot-and-mouth disease virus [PDF]

open access: yes, 2016
The replication of foot-and-mouth disease virus (FMDV) is dependent on the virus-encoded 3C protease (3Cpro). As in other picornaviruses, 3Cpro performs most of the proteolytic processing of the polyprotein expressed from the single open reading frame in
Curry, S, Leen, EN, Maree, FF, Yang, J
core   +4 more sources

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

A Coding Sequence-Embedded Principle Governs Translational Reading Frame Fidelity

open access: yesResearch, 2018
Upon initiation at a start codon, the ribosome must maintain the correct reading frame for hundreds of codons in order to produce functional proteins. While some sequence elements are able to trigger programmed ribosomal frameshifting (PRF), very little ...
Ji Wan   +4 more
doaj   +1 more source

uPEPperoni: An online tool for upstream open reading frame location and analysis of transcript conservation

open access: yesBMC Bioinformatics, 2014
Several small open reading frames located within the 5′ untranslated regions of mRNAs have recently been shown to be translated. In humans, about 50% of mRNAs contain at least one upstream open reading frame representing a large resource of coding ...
Adam Skarshewski   +6 more
semanticscholar   +1 more source

Identification of Open Reading Frames in Schizosaccharomyces pombe cDNAs [PDF]

open access: yesDNA Research, 1997
A total of 214 non-overlapping cDNA clones from Schizosaccharomyces pombe were selected and completely sequenced. The clones not previously reported were divided into the following three groups: 1) homologous to Saccharomyces cerevisiae genes (139 clones); 2) homologous to genes from other organisms but not to those from Sac. cerevisiae (4 clones); and
Hiroshi Nojima   +4 more
openaire   +3 more sources

Novel insights into noncanonical open reading frames in cancer

open access: yesBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2022
With technological advances, previously neglected noncanonical open reading frames (nORFs) are drawing ever-increasing attention. However, the translation potential of numerous putative nORFs remains elusive, and the functions of noncanonical peptides have not been systemically summarized.
Yihan, Liu, Shan, Zeng, Minghua, Wu
openaire   +2 more sources

Flatworms have lost the right open reading frame kinase 3 gene during evolution [PDF]

open access: yes, 2015
All multicellular organisms studied to date have three right open reading frame kinase genes (designated riok-1, riok-2 and riok-3). Current evidence indicates that riok-1 and riok-2 have essential roles in ribosome biosynthesis, and that the riok-3 gene
Amani, Parisa   +9 more
core   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Stability of RNA quadruplex in open reading frame determines proteolysis of human estrogen receptor α

open access: yesNucleic Acids Research, 2013
mRNAs encodes not only information that determines amino acid sequences but also additional layers of information that regulate the translational processes.
T. Endoh, Yu Kawasaki, N. Sugimoto
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy