Results 71 to 80 of about 1,409,999 (372)

An open reading frame upstream from the nifH gene of Klebsiella pneumoniae [PDF]

open access: yes, 1983
An open reading frame upstream from nifHDK operon of Klebsiella pneumoniae had been described. The orientation of this open reading frame is opposite to that of nifHDK and sequence homology was found between the open reading frame promoter and the ...
Kong, Qiu-tong   +3 more
core  

A Novel 3-Methyladenine DNA Glycosylase from Helicobacter pylori Defines a New Class within the Endonuclease III Family of Base Excision Repair Glycosylases [PDF]

open access: yes, 2000
The cloning, purification, and characterization of MagIII, a 3-methyladenine DNA glycosylase from Helicobacter pylori, is presented in this paper. Sequence analysis of the genome of this pathogen failed to identify open reading frames potentially coding ...
Boiteux, Serge   +5 more
core   +1 more source

Upstream Open Reading Frames as Regulators of mRNA Translation [PDF]

open access: yesMolecular and Cellular Biology, 2000
Continuing discoveries of new and surprising mechanisms of gene regulation suggest that our understanding of this complex and ubiquitous biological process remains incomplete. Emerging examples illustrate that many and perhaps all genes are regulated at multiple steps including transcription, posttranscriptional processing, nuclear export and ...
Adam P. Geballe   +2 more
openaire   +2 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Molecular cloning, characterization, and expression of two 5-HTRs from the pearl oyster Pinctada fucata martensii

open access: yesFrontiers in Marine Science, 2022
The receptors of serotonin, also known as 5-hydroxytryptamine receptor (5-HTR) can mediate regulatory metamorphosis processes in a variety of mollusks.
Shaojie Zhu   +10 more
doaj   +1 more source

Stability of RNA quadruplex in open reading frame determines proteolysis of human estrogen receptor α

open access: yesNucleic Acids Research, 2013
mRNAs encodes not only information that determines amino acid sequences but also additional layers of information that regulate the translational processes.
T. Endoh, Yu Kawasaki, N. Sugimoto
semanticscholar   +1 more source

Translational control of Nrf2 within the open reading frame [PDF]

open access: yesBiochemical and Biophysical Research Communications, 2013
Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) is a transcription factor that is essential for the regulation of an effective antioxidant and detoxifying response. The regulation of its activity can occur at transcription, translation and post-translational levels.
Carlos A. Barrero   +2 more
openaire   +3 more sources

Novel insights into noncanonical open reading frames in cancer

open access: yesBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2022
With technological advances, previously neglected noncanonical open reading frames (nORFs) are drawing ever-increasing attention. However, the translation potential of numerous putative nORFs remains elusive, and the functions of noncanonical peptides have not been systemically summarized.
Yihan, Liu, Shan, Zeng, Minghua, Wu
openaire   +2 more sources

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

A Coding Sequence-Embedded Principle Governs Translational Reading Frame Fidelity

open access: yesResearch, 2018
Upon initiation at a start codon, the ribosome must maintain the correct reading frame for hundreds of codons in order to produce functional proteins. While some sequence elements are able to trigger programmed ribosomal frameshifting (PRF), very little ...
Ji Wan   +4 more
doaj   +1 more source

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