Learning gradients on manifolds
A common belief in high-dimensional data analysis is that data are concentrated on a low-dimensional manifold. This motivates simultaneous dimension reduction and regression on manifolds.
Mukherjee, Sayan +2 more
core +1 more source
The Role of Osteocytes in Targeted Bone Remodeling: A Mathematical Model [PDF]
Until recently many studies of bone remodeling at the cellular level have focused on the behavior of mature osteoblasts and osteoclasts, and their respective precursor cells, with the role of osteocytes and bone lining cells left largely unexplored. This
Ayati, Bruce P. +3 more
core +3 more sources
The characteristics of collagen‐induced rheumatoid arthritis in macaques and the changes of heart
The disease progression in CIA macaques was categorized into three stages: IIR (days 14–34): The indicators related to rheumatoid arthritis and the levels of immunoglobulin were all elevated. There was a small amount of joint effusion, edema and mild synovial hyperplasia. No joint swelling was observed by naked eye.
Lei Zhang +8 more
wiley +1 more source
Osteoprotegerin levels in ST-elevation myocardial infarction: Temporal profile and association with myocardial injury and left ventricular function. [PDF]
BACKGROUND:Elevated levels of osteoprotegerin (OPG) have been associated with adverse outcomes in ST-elevation myocardial infarction (STEMI). However, the role of OPG in myocardial injury and adverse remodeling in STEMI patients remains unclear. The aims
Christian Shetelig +8 more
doaj +1 more source
This article discusses parachurch (hereinafter referred to as the Organisasi Pendamping Gereja / OPG). According to Jerry White, a parachurch is all forms of spiritual ministry whose organizational structure is not under the control of the church ...
Tommy Indarto
doaj +1 more source
Maximizing Maximal Angles for Plane Straight-Line Graphs [PDF]
Let $G=(S, E)$ be a plane straight-line graph on a finite point set $S\subset\R^2$ in general position. The incident angles of a vertex $p \in S$ of $G$ are the angles between any two edges of $G$ that appear consecutively in the circular order of the ...
A. Aggarwal +11 more
core +10 more sources
Ontogeny of murine bony semicircular canal form
Abstract The labyrinthine geometry and functional anatomy of the semicircular canals have intrigued scientists for decades, and there has been considerable interest in understanding how these complex structures grow and develop with evidence emerging from human studies that size maturation occurs exceptionally early by comparison with other systems ...
Marcela Cárdenas‐Serna +1 more
wiley +1 more source
RANKL/OPG ratio regulates odontoclastogenesis in damaged dental pulp
Bone-resorbing osteoclasts are regulated by the relative ratio of the differentiation factor, receptor activator NF-kappa B ligand (RANKL) and its decoy receptor, osteoprotegerin (OPG).
Daisuke Nishida +9 more
doaj +1 more source
Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang +6 more
wiley +1 more source
Estrogen activation of microglia underlies the sexually dimorphic differences in Nf1 optic glioma-induced retinal pathology [PDF]
Children with neurofibromatosis type 1 (NF1) develop low-grade brain tumors throughout the optic pathway. Nearly 50% of children with optic pathway gliomas (OPGs) experience visual impairment, and few regain their vision after chemotherapy.
Anne C. Solga +37 more
core +2 more sources

