Results 71 to 80 of about 128,638 (328)

The Kids Are Not Alright: Leveraging Existing Health Law to Attack the Opioid Crisis Upstream [PDF]

, 2019
The opioid crisis is now a nationwide epidemic, ravaging both rural and urban communities. The public health and economic consequences are staggering; recent estimates suggest the epidemic has contracted the U.S. labor market by over one million jobs and
Cannon, Yael
core   +2 more sources

Herbal highs: review on psychoactive effects and neuropharmacology [PDF]

, 2017
Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S, Orsolini, L, Pichini, S., Rotolo, Mc, Schifano, F, Tittarelli, R   +5 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Caenorhabditis elegans as a model system to identify therapeutics for alcohol use disorders [PDF]

, 2019
Alcohol use disorders (AUDs) cause serious problems in society and few effective treatments are available. Caenorhabditis elegans (C. elegans) is an excellent invertebrate model to study the neurobiological basis of human behavior with a conserved, fully
Bell, Richard L., Bredhold, Kristin E., Cheong, Mi C., Engleman, Eric A., Katner, Simon N., Neal-Beliveau, Bethany S., Steagall, Kevin B., III   +6 more
core   +1 more source

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances

Advanced Science, EarlyView.
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch, Roberto De Luca, Richard L Spinieli, Enrico Rillosi, Renner C Thomas, Samuel Sailesh, Nishta Gangeddula, Janayna D Lima, Sathyajit S Bandaru, Elda Arrigoni, Agustin Melo‐Carrillo, Rami Burstein, Stephen Thankachan, Satvinder Kaur   +13 more
wiley   +1 more source

Discharge locations after hospitalizations involving opioid use disorder among medicare beneficiaries

Addiction Science & Clinical Practice, 2022
Background Hospitalizations involving opioid use disorder (OUD) have been increasing among Medicare beneficiaries of all ages. With rising OUD-related acute care use comes the need to understand where post-acute care is provided and the capacities for ...
Patience Moyo, Melissa Eliot, Asghar Shah, Kimberly Goodyear, Eric Jutkowitz, Kali Thomas, Andrew R. Zullo   +6 more
doaj   +1 more source

Electrochemistry as a Tool for Redox‐Based Bio‐Information Processing

Advanced Science, EarlyView.
Redox is a modality that is native to biology and accessible to electronics through electrochemistry. Imposed electronic inputs are transduced into redox signals that can probe for bio‐information or actuate biological responses. Measured electronic output responses are analyzed to reveal actionable information.
Eunkyoung Kim, Chen‐yu Chen, Fauziah Rahma Zakaria, Dana Motabar, Mijeong Kang, Deanna L. Kelly, Alessandra Napolitano, William E. Bentley, Gregory F. Payne   +8 more
wiley   +1 more source

Comparing cognitive behavioral therapy and social prescribing in patients with loneliness on long-term opioid therapy to reduce opioid misuse: protocol for a randomized controlled trial

Addiction Science & Clinical Practice
Background Patients with chronic pain on opioids frequently experience loneliness, which is associated with poorer health outcomes and higher risk for opioid misuse and opioid use disorder. Given that almost half of opioids are prescribed in primary care,
Sebastian T. Tong, Kris Pui Kwan Ma, Ajla Pleho, Brennan Keiser, Chialing Hsu, Dawn M. Ehde, Mary C. Curran, Judith I. Tsui, Patrick J. Raue, Kari A. Stephens   +9 more
doaj   +1 more source

Putting Families First: How the Opioid Epidemic is Affecting Children and Families, and the Child Welfare Policy Options to Address It [PDF]

, 2019
: Opioids and Child Welfare Across the country, placements in foster care are rising. In 2016, the U.S. Department of Health and Human Services reported that 273,539 children in the U.S. entered foster care.
American Academy of Pediatrics Council on Foster Care, Adoption, and Kinship Care, Greiner, Mary V, Laris, Zach, Waite, Douglas   +3 more
core   +1 more source

Buprenorphine added on brief cognitive behavioral therapy for treatment of methamphetamine use disorder [PDF]

, 2018
Background: Methamphetamine (MA) use remains a major public health concern around the world. Recent findings suggest that buprenorphine may be helpful for cocaine use reduction. Moreover, animal studies described reduced dopamine peak effect following MA
Dean AJ, Hassani-Abharian P, Hollister LE, Karimlou M, Kirchmayer U, Kosten TR, Mello NK, Nejati V, Raistrick D, Rothenberg JL,     +10 more
core   +1 more source