Results 11 to 20 of about 697,718 (358)

Stigma as a fundamental hindrance to the United States opioid overdose crisis response. [PDF]

PLoS Medicine, 2019
Alexander Tsai and co-authors discuss the role of stigma in responses to the US opioid ...
Barnett, Michael L, Beletsky, Leo, Keyes, Katherine M, Kiang, Mathew V, McGinty, Emma E, Smith, Laramie R, Strathdee, Steffanie A, Tsai, Alexander C, Venkataramani, Atheendar S, Wakeman, Sarah E   +9 more
core   +3 more sources

Trends and Geographic Patterns in Drug and Synthetic Opioid Overdose Deaths — United States, 2013–2019

MMWR. Morbidity and mortality weekly report, 2021
Deaths involving synthetic opioids other than methadone (synthetic opioids), which largely consist of illicitly manufactured fentanyl; psychostimulants with abuse potential (e.g., methamphetamine); and cocaine have increased in recent years, particularly
C. Mattson, Lauren J. Tanz, K. Quinn, M. Kariisa, Priyam Patel, N. Davis   +5 more
semanticscholar   +1 more source

The rise of illicit fentanyls, stimulants and the fourth wave of the opioid overdose crisis

Current Opinion in Psychiatry, 2021
Purpose of review This review provides an update on recently published literature on the rise of illicit fentanyls, risks for overdose, combinations with other substances, e.g. stimulants, consequences, and treatment.
D. Ciccarone
semanticscholar   +1 more source

Use of Medication for Opioid Use Disorder Among Adults With Past-Year Opioid Use Disorder in the US, 2021

JAMA Network Open, 2023
This cross-sectional study uses data from the 2021 National Survey on Drug Use and Health to estimate the receipt of medication for opioid use disorder among US adults with past-year opioid use disorder.
Christopher M. Jones, B. Han, G. Baldwin, Emily B. Einstein, W. Compton   +4 more
semanticscholar   +1 more source

Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT Genotypes and Select Opioid Therapy

Clinical pharmacology and therapy, 2021
Opioids are mainly used to treat both acute and chronic pain. Several opioids are metabolized to some extent by CYP2D6 (codeine, tramadol, hydrocodone, oxycodone, and methadone).
K. Crews, A. Monte, Rachel Huddart, K. Caudle, E. Kharasch, A. Gaedigk, H. M. Dunnenberger, J. Leeder, J. Callaghan, C. Samer, T. Klein, Cyrine E. Haidar, S. V. Van Driest, G. Ruaño, K. Sangkuhl, L. Cavallari, D. Müller, C. Prows, M. Nagy, A. Somogyi, T. Skaar   +20 more
semanticscholar   +1 more source

Drug and Opioid-Involved Overdose Deaths — United States, 2017–2018

MMWR. Morbidity and mortality weekly report, 2020
Of the 70,237 drug overdose deaths in the United States in 2017, approximately two thirds (47,600) involved an opioid (1). In recent years, increases in opioid-involved overdose deaths have been driven primarily by deaths involving synthetic opioids ...
N. Wilson, M. Kariisa, P. Seth, Herschel Smith, N. Davis   +4 more
semanticscholar   +1 more source

Association of Intraoperative Opioid Administration With Postoperative Pain and Opioid Use

JAMA Surgery, 2023
Key Points Question What is the association between intraoperative opioid administration and postoperative pain and opioid use? Findings In this cohort study of 61 249 individuals undergoing surgery, greater intraoperative fentanyl and hydromorphone ...
Laura A. Santa Cruz Mercado, Ran Liu, Kishore Bharadwaj, Jasmine Johnson, Rodrigo Gutiérrez, P. Das, Gustavo Balanza, H. Deng, Akriti Pandit, Tom A. D. Stone, Teresa Macdonald, Caroline Horgan, Si Long Jenny Tou, T. Houle, E. Bittner, P. Purdon   +15 more
semanticscholar   +1 more source

Comparative Effectiveness of Different Treatment Pathways for Opioid Use Disorder

JAMA Network Open, 2020
This comparative effectiveness research study examines associations between opioid use disorder treatment pathways and overdose and opioid-related acute care use as proxies for opioid use disorder recurrence.
S. Wakeman, Marc R. Larochelle, O. Ameli, C. Chaisson, J. Mcpheeters, W. Crown, F. Azocar, Darshak M Sanghavi   +7 more
semanticscholar   +1 more source

Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017

MMWR. Morbidity and mortality weekly report, 2018
The 63,632 drug overdose deaths in the United States in 2016 represented a 21.4% increase from 2015; two thirds of these deaths involved an opioid (1).
Lawrence Scholl, P. Seth, M. Kariisa, N. Wilson, G. Baldwin   +4 more
semanticscholar   +1 more source

The Changing Opioid Crisis: development, challenges and opportunities

Molecular Psychiatry, 2020
The current opioid epidemic is one of the most severe public health crisis in US history. Responding to it has been difficult due to its rapidly changing nature and the severity of its associated outcomes. This review examines the origin and evolution of
N. Volkow, C. Blanco
semanticscholar   +1 more source