Trauma and acute care surgeons report prescribing less opioids over time. [PDF]
IntroductionConfronted with the opioid epidemic, surgeons must play a larger role to reduce risk of opioid abuse while managing acute pain. Having a better understanding of the beliefs and practices of trauma and acute care surgeons regarding discharge ...
Anderson, Jamie E +2 more
core +2 more sources
Postoperative opioid use following head and neck endocrine surgery: A multi‐center prospective study
Background Opioid abuse is widespread in North America and the over‐prescription of opioids are a contributing factor. The goal of this prospective study was to quantify over‐prescription rates, evaluate postoperative experiences of pain, and understand ...
Amr F. Hamour +9 more
doaj +1 more source
Effect of intravenous magnesium on postoperative pain control for major abdominal surgery: a randomized double-blinded study [PDF]
Background This study aimed to evaluate the postoperative analgesic effect of magnesium sulfate during abdominal surgery. Methods This randomized double-blinded study involved 84 patients candidates for abdominal surgery into two same groups.
Arash Peivandi Yazdi +2 more
doaj +1 more source
Development of an integrated cognitive behavioral therapy for anxiety and opioid use disorder: Study protocol and methods [PDF]
Opioid use disorder is a highly disabling psychiatric disorder, and is associated with both significant functional disruption and risk for negative health outcomes such as infectious disease and fatal overdose. Even among those who receive evidence-based
Barlow, David H. +5 more
core +1 more source
A good therapeutic alliance is relevant for healthcare providers exposed to patients’ suffering, especially since patients and physicians may understand the painful experience differently.
Barrachina Jordi +7 more
doaj +1 more source
BackgroundPectoralis nerve blocks (PECS) have been shown in numerous studies to be a safe and effective method to treat postoperative pain and reduce postoperative opioid consumption after breast surgery.
Alberto A. Uribe +9 more
doaj +1 more source
An opioid-like system regulating feeding behavior in C. elegans [PDF]
Neuropeptides are essential for the regulation of appetite. Here we show that neuropeptides could regulate feeding in mutants that lack neurotransmission from the motor neurons that stimulate feeding muscles. We identified nlp-24 by an RNAi screen of 115
Artyukhin, Alexander B. +3 more
core +3 more sources
In vitro and in vivo pharmacological activities of 14-o-phenylpropyloxymorphone, a potent mixed mu/delta/kappa-opioid receptor agonist with reduced constipation in mice [PDF]
Pain, particularly chronic pain, is still an unsolved medical condition. Central goals in pain control are to provide analgesia of adequate efficacy and to reduce complications associated with the currently available drugs.
Lattanzi, Roberta +4 more
core +2 more sources
Background The Confederated Tribes of the Grand Ronde Community of Oregon began a Mobile Medication Unit (MMU) as part of their Great Circle Recovery Opioid Treatment Program (OTP) to address elevated rates of opioid use disorder (OUD) among American ...
Kim A. Hoffman +7 more
doaj +1 more source
7‑hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects [PDF]
Mitragynina speciosa, more commonly known as kratom, is a plant native to Southeast Asia, the leaves of which have been used traditionally as a stimulant, analgesic, and treatment for opioid addiction.
Ansonoff, Michael +12 more
core +3 more sources

