Effects of high-frequency, high-intensity transcutaneous electrical nerve stimulation versus intravenous opioids for pain relief after gynecologic laparoscopic surgery: a randomized controlled study [PDF]
Korean Journal of Anesthesiology, 2018 Background The aim of the study was to compare the pain relieving effect and the time spent in the recovery unit after treatment with high frequency, high-intensity transcutaneous electrical nerve stimulation (TENS) or intravenous (IV) opioids after ...
Birgitta Platon +2 more
doaj +1 more source
Neonatal abstinence syndrome: Pharmacologic strategies for the mother and infant. [PDF]
, 2016 Opioid use in pregnancy has increased dramatically over the past decade. Since prenatal opioid use is associated with numerous obstetrical and neonatal complications, this now has become a major public health problem.
Davis, Jonathan M. +2 more
core +2 more sources
Opioid Receptors in Immune and Glial Cells-Implications for Pain Control [PDF]
, 2020 Opioid receptors comprise μ (MOP), δ (DOP), κ (KOP), and nociceptin/orphanin FQ (NOP) receptors. Opioids are agonists of MOP, DOP, and KOP receptors, whereas nociceptin/orphanin FQ (N/OFQ) is an agonist of NOP receptors.
Celik, Melih Ö., Machelska, Halina
core +1 more source
Opioid Use Disorder Documented at Delivery Hospitalization — United States, 1999–2014
MMWR. Morbidity and mortality weekly report, 2018 Opioid use by pregnant women represents a significant public health concern given the association of opioid exposure and adverse maternal and neonatal outcomes, including preterm labor, stillbirth, neonatal abstinence syndrome, and maternal mortality (1 ...
Sarah C. Haight +4 more
semanticscholar +1 more source
Development of an integrated cognitive behavioral therapy for anxiety and opioid use disorder: Study protocol and methods [PDF]
, 2017 Opioid use disorder is a highly disabling psychiatric disorder, and is associated with both significant functional disruption and risk for negative health outcomes such as infectious disease and fatal overdose. Even among those who receive evidence-based
Barlow, David H. +5 more
core +1 more source
Medication for Opioid Use Disorder After Nonfatal Opioid Overdose and Association With Mortality
Annals of Internal Medicine, 2018 The United States is in the midst of a crisis of opioid-related harms (1). Some efforts to address this crisis focus on expanding access to effective treatment of opioid use disorders (OUDs) (2).
Marc R. Larochelle +8 more
semanticscholar +1 more source
Opioid Crisis: No Easy Fix to Its Social and Economic Determinants.
American Journal of Public Health, 2018 The accepted wisdom about the US overdose crisis singles out prescribing as the causative vector. Although drug supply is a key factor, we posit that the crisis is fundamentally fueled by economic and social upheaval, its etiology closely linked to the ...
N. Dasgupta, L. Beletsky, D. Ciccarone
semanticscholar +1 more source
Addiction Science & Clinical Practice, 2022 Objective To characterize and address the opioid crisis disproportionately impacting rural U.S. regions. Methods The Rural Opioid Initiative (ROI) is a two-phase project to collect and harmonize quantitative and qualitative data and develop tailored ...
R. Jenkins +23 more
semanticscholar +1 more source
Structure of the μ Opioid Receptor-Gi Protein Complex
Nature, 2018 The μ-opioid receptor (μOR) is a G-protein-coupled receptor (GPCR) and the target of most clinically and recreationally used opioids. The induced positive effects of analgesia and euphoria are mediated by μOR signalling through the adenylyl cyclase ...
A. Koehl +16 more
semanticscholar +1 more source
Trauma and acute care surgeons report prescribing less opioids over time. [PDF]
, 2019 IntroductionConfronted with the opioid epidemic, surgeons must play a larger role to reduce risk of opioid abuse while managing acute pain. Having a better understanding of the beliefs and practices of trauma and acute care surgeons regarding discharge ...
Anderson, Jamie E +2 more
core +2 more sources