Results 31 to 40 of about 593,453 (414)
Neonatal abstinence syndrome: Pharmacologic strategies for the mother and infant. [PDF]
, 2016 Opioid use in pregnancy has increased dramatically over the past decade. Since prenatal opioid use is associated with numerous obstetrical and neonatal complications, this now has become a major public health problem.
Davis, Jonathan M. +2 more
core +2 more sources
Ingested placenta blocks the effect of morphine on gut transit in Long–Evans rats [PDF]
, 2004 Opioids produce antinociception, and ingested placenta or amniotic fluid modifies that antinociception. More specifically, ingested placenta enhances the antinociception produced by selective activation of central n-opioid or y-opioid receptors but ...
Corpening, Dr. James W. +2 more
core +1 more source
Pharmacological Prevention of Neonatal Opioid Withdrawal in a Pregnant Guinea Pig Model
Frontiers in Pharmacology, 2021 Newborns exposed to prenatal opioids often experience intense postnatal withdrawal after cessation of the opioid, called neonatal opioid withdrawal syndrome (NOWS), with limited pre- and postnatal therapeutic options available.
Alireza Safa +14 more
doaj +1 more source
Opioid Receptors in Immune and Glial Cells-Implications for Pain Control [PDF]
, 2020 Opioid receptors comprise μ (MOP), δ (DOP), κ (KOP), and nociceptin/orphanin FQ (NOP) receptors. Opioids are agonists of MOP, DOP, and KOP receptors, whereas nociceptin/orphanin FQ (N/OFQ) is an agonist of NOP receptors.
Celik, Melih Ö., Machelska, Halina
core +1 more source
Medication for Opioid Use Disorder After Nonfatal Opioid Overdose and Association With Mortality
Annals of Internal Medicine, 2018 The United States is in the midst of a crisis of opioid-related harms (1). Some efforts to address this crisis focus on expanding access to effective treatment of opioid use disorders (OUDs) (2).
Marc R. Larochelle +8 more
semanticscholar +1 more source
Frontiers in Medicine, 2022 BackgroundPectoralis nerve blocks (PECS) have been shown in numerous studies to be a safe and effective method to treat postoperative pain and reduce postoperative opioid consumption after breast surgery.
Alberto A. Uribe +9 more
doaj +1 more source
Opioid Use Disorder Documented at Delivery Hospitalization — United States, 1999–2014
MMWR. Morbidity and mortality weekly report, 2018 Opioid use by pregnant women represents a significant public health concern given the association of opioid exposure and adverse maternal and neonatal outcomes, including preterm labor, stillbirth, neonatal abstinence syndrome, and maternal mortality (1 ...
Sarah C. Haight +4 more
semanticscholar +1 more source
Opioid overdose, interventions, and challenges [PDF]
BioImpacts, 2022 This short letter briefly reviews the significance of opioid overdose as well as the existing approaches to combat the epidemic. It also signifies the importance of naloxone, its commercially available dosage forms, and the unmet need for developing safe
Samaneh Alaei, Hossein Omidian
doaj +1 more source
Trauma and acute care surgeons report prescribing less opioids over time. [PDF]
, 2019 IntroductionConfronted with the opioid epidemic, surgeons must play a larger role to reduce risk of opioid abuse while managing acute pain. Having a better understanding of the beliefs and practices of trauma and acute care surgeons regarding discharge ...
Anderson, Jamie E +2 more
core +2 more sources
Geographic Spillover Effects of Prescription Drug Monitoring Programs (PDMPs) [PDF]
arXiv, 2021 Prescription Drug Monitoring Programs (PDMPs) seek to potentially reduce opioid misuse by restricting the sale of opioids in a state. We examine discontinuities along state borders, where one side may have a PDMP and the other side may not. We find that electronic PDMP implementation, whereby doctors and pharmacists can observe a patient's opioid ...
arxiv