Results 21 to 30 of about 7,007,196 (291)

Use of sustained release dextroamphetamine for the treatment of stimulant use disorder in the setting of injectable opioid agonist treatment in Canada: a case report

Harm Reduction Journal, 2021
Background For people with opioid use disorder who are not responding to oral opioid agonist treatment, evidence supports the effectiveness of injectable opioid agonist treatment with injectable hydromorphone (an opioid analgesic) and diacetylmorphine ...
Heather Palis, Scott MacDonald, Jennifer Jun, Eugenia Oviedo-Joekes   +3 more
doaj   +1 more source

Ligand-Specific Regulation of the Endogenous Mu-Opioid Receptor by Chronic Treatment with Mu-Opioid Peptide Agonist [PDF]

, 2013
Since the discovery of the endomorphins (EM), the postulated endogenous peptide agonists of the mu-opioid receptors, several analogues have been synthesized to improve their binding and pharmacological profiles.
Murányi Marianna, Szűcs, Mária, Dochnal Roberta, Kicsi Emese, Kicsi, Emese Gabriella, Fábián Gabriella, Szabó Gyula, Szabó, Gyula, Zentai, András, Bozó, Beáta, Fábián, Gabriella, Birkás Erika, Cinar Resat, Bozó Bea, Birkás, Erika, Kékesi Orsolya Sára, Cinar, Resat, Tóth, Géza, Mácsai Mónika, Mácsai, Mónika, Kékesi, Orsolya, Dochnal, Roberta Beatrix, Tóth Géza, Szűcs Mária, Murányi, Marianna, Zentai András   +25 more
core   +2 more sources

The impact of opioid agonist treatment on fatal and non-fatal drug overdose among people with a history of opioid dependence in NSW, Australia, 2001-2018: findings from the OATS retrospective linkage study.

International Journal of Population Data Science, 2022
Objectives There are critical periods of mortality risk at onset and cessation of opioid agonist treatment. We aim to determine whether non-fatal overdose followed the same pattern as fatal overdose, comparing the first 4 weeks of treatment and ...
Nicola Jones, Louisa Degenhardt, Matthew Hickman, Suzanne Nielsen, Sarah Larney, Timothy Dobbins, Robert Ali   +6 more
doaj   +1 more source

First-line opioid agonist treatment as prevention against assisting others in initiating injection drug use: A longitudinal cohort study of people who inject drugs in Vancouver, Canada

Drug and Alcohol Dependence Reports, 2023
Background: Among people who inject drugs, frequent injecting and experiencing withdrawal are associated with facilitating others’ first injections. As these factors may reflect an underlying substance use disorder, we investigated whether first-line ...
Zachary Bouck, Andrea C. Tricco, Laura C. Rosella, Hailey R. Banack, Matthew P. Fox, Robert W. Platt, M-J Milloy, Kora DeBeck, Kanna Hayashi, Dan Werb   +9 more
doaj   +1 more source

A cohort study evaluating the association between concurrent mental disorders, mortality, morbidity, and continuous treatment retention for patients in opioid agonist treatment (OAT) across Ontario, Canada, using administrative health data

Harm Reduction Journal, 2020
Background Due to the high prevalence of mental disorders among people with opioid use disorder, the objective of this study was to determine the association between concurrent mental disorders, mortality, morbidity, and continuous treatment retention ...
Kristen A. Morin, Joseph K. Eibl, Graham Gauthier, Brian Rush, Christopher Mushquash, Nancy E. Lightfoot, David C. Marsh   +6 more
doaj   +1 more source

Nontraditional Alcohol and Opioid Agonist Treatment Interventions [PDF]

Medical Clinics of North America, 2018
Despite the availability of effective medications and psychosocial interventions for the management of a substance use disorder, some individuals repeatedly fail the most aggressive treatment regimens. For such individuals, alternative treatment options exist seeking to mitigate the negative consequences of the use of harmful substances.
Christopher, Fairgrieve, Nadia, Fairbairn, Jeffrey H, Samet, Seonaid, Nolan   +3 more
openaire   +2 more sources

Opioid agonist treatment for pharmaceutical opioid dependent people

Cochrane Database of Systematic Reviews, 2014
There are increasing concerns regarding pharmaceutical opioid harms including overdose and dependence, with an associated increase in treatment demand. People dependent on pharmaceutical opioids appear to differ in important ways from people who use heroin, yet most opioid agonist treatment research has been conducted in people who use heroin.To assess
Nielsen, S, Larance, B, Degenhardt, L, Gowing, L, Kehler, C, Lintzeris, N   +5 more
openaire   +3 more sources

Concurrent psychiatry for patients enrolled in opioid agonist treatment: a propensity score matched cohort study in Ontario Canada

Substance Abuse Treatment, Prevention, and Policy, 2019
Objective The objective was to characterize the relationship between geography, concurrent psychiatric services, all-cause mortality, and acute health care use for individuals enrolled in Opioid Agonist Treatment, in Ontario, Canada. Methods We conducted
Kristen A. Morin, Joseph K. Eibl, Joseph M. Caswell, Graham Gauthier, Brian Rush, Christopher Mushquash, Nancy E. Lightfoot, David C. Marsh   +7 more
doaj   +1 more source

Effect of fruit smoothie supplementation on psychological distress among people with substance use disorders receiving opioid agonist therapy: protocol for a randomised controlled trial (FruktBAR)

BMC Nutrition, 2022
Background People with substance use disorders generally have unhealthy diets, including limited intake of fruit and vegetables. Evidence shows substantial health benefits from increasing fruit and vegetable consumption on various indicators and possibly
Lars T. Fadnes, Einar Furulund, Karl Trygve Druckrey-Fiskaaen, Tesfaye Madebo, Jørn Henrik Vold, Maria Olsvold, Marianne Cook Pierron, Siv-Elin Leirvåg Carlsen, Rune Blomhoff, Torgeir Gilje Lid, for the ATLAS4LAR Study Group   +10 more
doaj   +1 more source

Psychosocial combined with agonist maintenance treatments versus agonist maintenance treatments alone for treatment of opioid dependence [PDF]

Cochrane Database of Systematic Reviews, 2004
Maintenance treatments are effective in retaining patients in treatment and suppressing heroin use. Questions remain regarding the efficacy of additional psychosocial services offered by most maintenance programs.To evaluate the effectiveness of any psychosocial plus any agonist maintenance treatment versus standard agonist treatment for opiate ...
L, Amato, S, Minozzi, M, Davoli, S, Vecchi, M, Ferri, S, Mayet   +5 more
openaire   +5 more sources