Results 31 to 40 of about 7,007,196 (291)

Evaluating the effectiveness of concurrent opioid agonist treatment and physician-based mental health services for patients with mental disorders in Ontario, Canada.

open access: yesPLoS ONE, 2020
ObjectiveThe objective of this study was to evaluate the relationship between concurrent physician-based mental health services, all-cause mortality, and acute health service use for individuals enrolled in Opioid Agonist Treatment in Ontario, Canada ...
Kristen A Morin   +6 more
doaj   +1 more source

Intranasal Oxytocin for Stimulant Use Disorder Among Male Veterans Enrolled in an Opioid Treatment Program: A Randomized Controlled Trial

open access: yesFrontiers in Psychiatry, 2022
The increasing prevalence of illicit stimulant use among those in opioid treatment programs poses a significant risk to public health, stimulant users have the lowest rate of retention and poorest outcomes among those in addiction treatment, and current ...
Christopher S. Stauffer   +8 more
doaj   +1 more source

BUPRENORPHINE IN OPIOID ADDICTION TEREATMENT: STUDIES WITH METHADONE COMPARISON

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Methadone maintenance treatment is the most widely used pharmacological treatment approach for opioid addiction in many countries. In spite of many benefits that was gained after the usage of full agonist methadone, especially high numbers of patients ...
E.Cüneyt Evren   +3 more
doaj  

Treatment retention in opioid agonist therapy: comparison of methadone versus buprenorphine/naloxone by analysis of daily-witnessed dispensed medication in a Canadian Province

open access: yesBMC Psychiatry, 2022
Background The last decade has shown a remarkable increase in the rates of illicit opioid use in Canada and internationally, which is associated with large increases in opioid related morbidity and mortality.
Joseph Sadek, Joseph Saunders
doaj   +1 more source

Suboxone: History, controversy, and open questions

open access: yesFrontiers in Psychiatry, 2022
There are more than 200 opioid overdose deaths each day in the US. In combating this epidemic we look to available treatment tools. Here, we find only three medications approved by the Food and Drug Administration (FDA) for the treatment of opioid use ...
Andy Sivils   +3 more
doaj   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

open access: yesAngewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma   +5 more
wiley   +2 more sources

Opiate agonist treatment to improve health of individuals with opioid use disorder in Lebanon

open access: yesHarm Reduction Journal, 2017
Background Opioid agonist therapy has been widely used to reduce harms among individuals with opioid use disorder but its effectiveness has not been evaluated in the Middle East North African (MENA) region.
Ali Ghaddar, Zeinab Abbas, Ramzi Haddad
doaj   +1 more source

Changes and trends in medication-assisted treatment in Israel

open access: yesIsrael Journal of Health Policy Research, 2023
Background As opioid prescription in Israel is increasing, there is a growing need for monitoring opioid use disorder and providing opioid agonist therapy.
Adi Marom, Iris Levy, Paola Rosca
doaj   +1 more source

Mortality during opioid agonist treatment in Norway: A comprehensive study of the years 2014 and 2015

open access: yes, 2022
Although opioid agonist treatment (OAT) substantially reduces morbidity and mortality in individuals with opioid dependence, mortality is still higher than in the general population.
Bech, Anne Berit
core   +1 more source

Feasibility of Testing Client Preferences for Accessing Injectable Opioid Agonist Treatment (iOAT): A Pilot Study

open access: yesPatient Preference and Adherence, 2022
Sophia Dobischok,1 Rebecca K Metcalfe,1 Elizabeth Angela Matzinger,1 Kurt Lock,1,2 Scott Harrison,3 Scott MacDonald,3 Sherif Amara,4 Martin T Schechter,1,5 Nick Bansback,1,5 Eugenia Oviedo-Joekes1,5 1Centre for Health Evaluation & Outcome Sciences ...
Dobischok S   +9 more
doaj  

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