Results 1 to 10 of about 418,205 (191)

Endogenous Opioid Peptides and Alternatively Spliced Mu Opioid Receptor Seven Transmembrane Carboxyl-Terminal Variants. [PDF]

open access: yesInt J Mol Sci, 2021
There exist three main types of endogenous opioid peptides, enkephalins, dynorphins and β-endorphin, all of which are derived from their precursors. These endogenous opioid peptides act through opioid receptors, including mu opioid receptor (MOR), delta ...
Abrimian A, Kraft T, Pan YX.
europepmc   +2 more sources

Genetically Engineered Human Mesenchymal Stem Cells Produce Met-Enkephalin at Augmented Higher Levels in Vitro

open access: yesCell Transplantation, 2006
We have reported that transplantation of adrenal medullary chromaffin cells that release endogenous opioid peptides into pain modulatory regions in the CNS produce significant antinociceptive effects in patients with terminal cancer pain.
Ikuko Sugaya   +3 more
doaj   +1 more source

THE EFFECT OF VASOPRESSIN IN ACUPUNCTURE ANALGESIUA

open access: yes针刺研究, 1988
Arg-Vasopressin (AVP)has obvious analgesic effect.This effect is not depressed by nalxone (NX),an antagonist of opiate receptor.It was observed that concentration of Leu-enkephalin (LEK) was decreased and catecholamines (CAS) were elevated ...
Liu Qi Han Wei Zhao Jianzhu
doaj   +2 more sources

In Vivo Regulation of the μ Opioid Receptor: Role of the Endogenous Opioid Agents

open access: yesMolecular Medicine, 2013
It is well known that genotypic differences can account for the subject-specific responses to opiate administration. In this regard, the basal activity of the endogenous system (either at the receptor or ligand level) can modulate the effects of ...
Veronica Gonzalez-Nunez   +3 more
doaj   +1 more source

Molecular docking study of Papaver alkaloids to some alkaloid receptors [PDF]

open access: yesResearch Journal of Pharmacognosy, 2017
Background and objectives: More than 40 different alkaloids have been obtained from opium the most important of which are morphine, codeine, papaverine, noscapine and tabaine.
A. Nofallah   +3 more
doaj  

Peptidomics and pharmacological profiling of Odontobuthus doriae (Buthidae) scorpion venom at the kappa opioid receptor

open access: yesScientific Reports
Scorpion venoms are rich in bioactive peptides, many of which act on ion channels and neurotransmitter systems, yet their capacity to interact with G protein-coupled receptors (GPCRs) has been largely unexplored.
Adel Abdollahnia   +6 more
doaj   +1 more source

The Role of Endogenous Beta-Endorphin and Enkephalins in the Crosstalk Between Ethanol and Morphine

open access: yesPharmaceuticals
Background: There is clinical concern about the combined use of alcohol and opiates. Several lines of evidence support an interaction between alcohol and the endogenous opioid system.
Andy Tseng   +3 more
doaj   +1 more source

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