Results 151 to 160 of about 1,054,479 (288)

Evidence for a Dual Mechanism in the Anesthetic Action of an Opioid Peptide [PDF]

, 1985
Barbara A. Dodson, Keith W. Miller
openalex   +1 more source

Safety and tolerability of ubrogepant for the acute treatment of migraine in participants taking atogepant for the preventive treatment of episodic migraine: Results from the TANDEM study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To evaluate the safety and tolerability of ubrogepant for the acute treatment of migraine in participants taking atogepant for the preventive treatment of episodic migraine (EM). Background Atogepant is an oral calcitonin gene‐related peptide (CGRP) receptor antagonist approved for the preventive treatment of migraine in adults and ...
Jessica Ailani, Richard B. Lipton, Andrew M. Blumenfeld, Laszlo Mechtler, Brad C. Klein, Molly Yizeng He, Jonathan H. Smith, Joel M. Trugman, Rosa de Abreu Ferreira, Elimor Brand‐Schieber   +9 more
wiley   +1 more source

Investigating the importance of social vulnerability in opioid-related mortality across the United States [PDF]

arXiv
The opioid crisis remains a critical public health challenge in the United States. Despite national efforts to reduce opioid prescribing rates by nearly 45\% between 2011 and 2021, opioid overdose deaths more than tripled during this same period. This alarming trend reflects a major shift in the crisis, with illegal opioids now driving the majority of ...
arxiv  

THE NEUROENDOCRINOLOGY OF OPIOID PEPTIDES

British Medical Bulletin, 1983
Grossman, A, Rees, L
openaire   +4 more sources

Effect of erenumab versus other migraine preventive medications on cardiovascular and cerebrovascular outcomes: A United States claims database‐based observational cohort study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To estimate the real‐world risk of cardiovascular events among patients with migraine treated with erenumab and other migraine preventive medications. Background Migraine preventive treatment with calcitonin gene‐related peptide (CGRP) pathway inhibitors, such as erenumab and others, may theoretically result in cardiovascular effects
David W. Dodick, Stewart J. Tepper, Jessica Ailani, Ani C. Khodavirdi, Nico Pannacciulli, Alan Fu, Shia T. Kent, Karminder Gill, Robert Urman, Sam S. Oh   +9 more
wiley   +1 more source

Opioid peptides derived from food proteins. The exorphins

, 1979
C. Zioudrou, Richard A. Streaty, Werner A. Klee   +2 more
openalex   +1 more source

Neuroendocrine mechanisms responsible for elevated gonadotrophin‐releasing hormone and luteinising hormone pulses in polycystic ovary syndrome

Journal of Neuroendocrinology, EarlyView.
Abstract Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility in premenopausal individuals with ovaries worldwide. Despite the diagnostic features of anovulation, ovarian cysts, and hyperandrogenemia, which indicate that ovary dysfunction is the cause of the syndrome, changes in central neuroendocrine circuits are a ...
Aleisha M. Moore
wiley   +1 more source

Release of bioactive peptides from whey proteins across digestion in adult humans and a static in vitro digestion model

Journal of Functional Foods
Proteolysis of whey proteins during gastrointestinal digestion releases bioactive peptides with potential health benefits. Our study examined whey-derived peptide release after digestion under static in vitro conditions and in three adults following whey
Suwimon Sutantawong, Bum Jin Kim, Russell F. Kuhfeld, Yunyao Qu, David C. Dallas   +4 more
doaj  

A Comparison of Veterans with Problematic Opioid Use Identified through Natural Language Processing of Clinical Notes versus Using Diagnostic Codes [PDF]

arXiv
Background: Electronic health records (EHRs) are a data source for opioid research. Opioid use disorder is known to be under-coded as a diagnosis, yet problematic opioid use can be documented in clinical notes. Objectives: Our goals were 1) to identify problematic opioid use from a full range of clinical notes; and 2) to compare the characteristics ...
arxiv  

Proteomic analysis of plasma proteins during fentanyl withdrawal in ovariectomized female rats with and without estradiol

Journal of Neuroendocrinology, EarlyView.
Abstract Evidence from both clinical and preclinical studies indicates that females experience a faster progression to drug addiction and more severe addiction‐related health effects compared with males. Estradiol (E2) plays a critical role in these sex differences.
Patricia Sinclair, Navdeep S. Dhanjal, E. Blair Towers, Wendy J. Lynch, Nadine Kabbani   +4 more
wiley   +1 more source