Results 51 to 60 of about 1,088,006 (377)
British Journal of Pharmacology, EarlyView., 2023 Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi +6 more
wiley +1 more source
Peptidomic and glycomic profiling of commercial dairy products: identification, quantification and potential bioactivities. [PDF]
, 2019 Peptidomics and glycomics are recently established disciplines enabling researchers to characterize functional characteristics of foods at a molecular level.
Barile, Daniela +4 more
core +2 more sources
In Silico and In Vitro Analysis of Multifunctionality of Animal Food-Derived Peptides
Foods, 2020 Currently, the associations between oxidative stress, inflammation, hypertension, and metabolic disturbances and non-communicable diseases are very well known.
Lourdes Amigo +2 more
doaj +1 more source
Peripherally Acting Opioids in Orofacial Pain
Frontiers in Neuroscience, 2021 The activation of opioid receptors by exogenous or endogenous opioids can produce significant analgesic effects in peripheral tissues. Numerous researchers have demonstrated the expression of peripheral opioid receptors (PORs) and endogenous opioid ...
Qing Liu +10 more
doaj +1 more source
Opioid peptides and metabolic regulation [PDF]
Diabetologia, 1988 La liaison entre opioides et obesite pourrait passer par des anomalies de l'insulino-secretion puisque une augmentation de la sensibilite des cellules B pancreatiques a la beta-endorphine a ete demontree chez les sujets obeses. Une profonde alteration du systeme opioide est presente dans le diabete sans que l'on puisse dire encore si cela represente un
GIUGLIANO, Dario +3 more
openaire +4 more sources
Investigating the KNDy hypothesis in humans by co-administration of kisspeptin, neurokinin B and naltrexone in men [PDF]
, 2016 Context: A subpopulation of hypothalamic neurons co-localise three neuropeptides namely kisspeptin, neurokinin B (NKB) and dynorphin collectively termed KNDy neurons. Animal studies suggest they interact to affect pulsatile GnRH release (KNDy hypothesis);
Abbara, A +11 more
core +1 more source
Molecules, 2020 The macrocyclic tetrapeptide cyclo[Phe-d-Pro-Phe-Trp] (CJ-15,208) and its stereoisomer cyclo[Phe-d-Pro-Phe-d-Trp] exhibit different opioid activity profiles in vivo.
Ariana C. Brice-Tutt +7 more
doaj +1 more source
Rubsicolins are naturally occurring G-protein-biased delta opioid receptor peptides
bioRxiv, 2018 The impact that β-arrestin proteins have on G-protein-coupled receptor trafficking, signaling and physiological behavior has gained much appreciation over the past decade.
Robert J. Cassell +6 more
semanticscholar +1 more source
Thymosin Beta 4 Is Involved in the Development of Electroacupuncture Tolerance
Frontiers in Cellular Neuroscience, 2019 Background: Electroacupuncture (EA) tolerance, a negative therapeutic effect, is a gradual decline in antinociception because of its repeated or prolonged use.
Juan Wan +6 more
doaj +1 more source
Geographic Spillover Effects of Prescription Drug Monitoring Programs (PDMPs) [PDF]
arXiv, 2021 Prescription Drug Monitoring Programs (PDMPs) seek to potentially reduce opioid misuse by restricting the sale of opioids in a state. We examine discontinuities along state borders, where one side may have a PDMP and the other side may not. We find that electronic PDMP implementation, whereby doctors and pharmacists can observe a patient's opioid ...
arxiv